STRINGSTRING
KLRD1 KLRD1 CTLA4 CTLA4 IL2 IL2 POU5F1 POU5F1 POU5F1-2 POU5F1-2 EGF EGF GDNF GDNF AFP AFP ALB ALB FGF4 FGF4 INS INS PTPRC PTPRC SOX2 SOX2 MYL2 MYL2 IFNG IFNG PAX6 PAX6 CD47 CD47 FGF2 FGF2 BDNF BDNF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KLRD1CD94-B. (180 aa)
CTLA4Cytotoxic T-lymphocyte associated protein 4. (223 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
POU5F1POU-specific domain-containing protein. (484 aa)
POU5F1-2Uncharacterized protein. (146 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
GDNFGlial cell derived neurotrophic factor. (228 aa)
AFPAlpha fetoprotein. (609 aa)
ALBAlbumin. (608 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (108 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1252 aa)
SOX2Transcription factor SOX-2. (319 aa)
MYL2Myosin light chain 2. (165 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family. (166 aa)
PAX6Paired box 6. (472 aa)
CD47CD47 molecule. (348 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (326 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (330 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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