Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGO2 | DICER1 | ENSCJAP00000056892 | ENSCJAP00000051203 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Endoribonuclease Dicer isoform 1; Belongs to the helicase family. Dicer subfamily. | 0.990 |
| AGO2 | DROSHA | ENSCJAP00000056892 | ENSCJAP00000035201 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Ribonuclease 3 isoform 1. | 0.970 |
| AGO2 | PTEN | ENSCJAP00000056892 | ENSCJAP00000054409 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | 0.510 |
| AGO2 | SIRT1 | ENSCJAP00000056892 | ENSCJAP00000046567 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Sirtuin 1. | 0.477 |
| AGO2 | TARBP2 | ENSCJAP00000056892 | ENSCJAP00000034713 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] | 0.986 |
| AGO2 | UPF1 | ENSCJAP00000056892 | ENSCJAP00000036494 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | UPF1 RNA helicase and ATPase. | 0.700 |
| AGO2 | XPO5 | ENSCJAP00000056892 | ENSCJAP00000045858 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Exportin 5. | 0.917 |
| ATP5MC1 | COX5A | ENSCJAP00000068732 | ENSCJAP00000057446 | ATP synthase lipid-binding protein, mitochondrial; Belongs to the ATPase C chain family. | Uncharacterized protein. | 0.549 |
| ATP5MC1 | LOC100390127 | ENSCJAP00000068732 | ENSCJAP00000018798 | ATP synthase lipid-binding protein, mitochondrial; Belongs to the ATPase C chain family. | Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. | 0.403 |
| CASP9 | LOC100401718 | ENSCJAP00000016114 | ENSCJAP00000061447 | Caspase 9; Belongs to the peptidase C14A family. | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.999 |
| CASP9 | LOC100406761 | ENSCJAP00000016114 | ENSCJAP00000058896 | Caspase 9; Belongs to the peptidase C14A family. | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.999 |
| CASP9 | LOC100413276 | ENSCJAP00000016114 | ENSCJAP00000056047 | Caspase 9; Belongs to the peptidase C14A family. | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.999 |
| CASP9 | LOC108593648 | ENSCJAP00000016114 | ENSCJAP00000063186 | Caspase 9; Belongs to the peptidase C14A family. | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.999 |
| CASP9 | NFE2L2 | ENSCJAP00000016114 | ENSCJAP00000078532 | Caspase 9; Belongs to the peptidase C14A family. | Nuclear factor, erythroid 2 like 2. | 0.649 |
| CASP9 | PTEN | ENSCJAP00000016114 | ENSCJAP00000054409 | Caspase 9; Belongs to the peptidase C14A family. | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. | 0.468 |
| CASP9 | SIRT1 | ENSCJAP00000016114 | ENSCJAP00000046567 | Caspase 9; Belongs to the peptidase C14A family. | Sirtuin 1. | 0.446 |
| CBFB | SMAD2 | ENSCJAP00000055772 | ENSCJAP00000008504 | Core-binding factor subunit beta isoform 1. | Mothers against decapentaplegic homolog. | 0.407 |
| COX11 | COX5A | ENSCJAP00000073068 | ENSCJAP00000057446 | Cytochrome c oxidase copper chaperone COX11. | Uncharacterized protein. | 0.475 |
| COX11 | LOC100401718 | ENSCJAP00000073068 | ENSCJAP00000061447 | Cytochrome c oxidase copper chaperone COX11. | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.535 |
| COX11 | LOC100406761 | ENSCJAP00000073068 | ENSCJAP00000058896 | Cytochrome c oxidase copper chaperone COX11. | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. | 0.535 |
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