STRINGSTRING
ITK ITK PDGFRA PDGFRA LCK LCK ERBB2 ERBB2 F7HFW4_CALJA F7HFW4_CALJA MAP3K11 MAP3K11 EPHB1 EPHB1 TIE1 TIE1 BLK BLK ROS1 ROS1 MST1R MST1R FRK FRK BTK BTK FYN FYN MET MET PTK7 PTK7 SYK SYK EPHB2 EPHB2 EPHA8 EPHA8 INSRR INSRR IGF1R IGF1R TYK2 TYK2 FGFR4 FGFR4 EPHA2 EPHA2 EPHA6 EPHA6 ALK ALK FGR FGR FES FES SRMS SRMS ZAP70 ZAP70 ERBB3 ERBB3 EPHA4 EPHA4 NTRK2 NTRK2 MAP3K10 MAP3K10 MAP3K9 MAP3K9 EPHB4 EPHB4 MATK MATK FER FER RET RET TNK1 TNK1 MERTK MERTK ROR1 ROR1 LYN LYN JAK1 JAK1 MAP3K21 MAP3K21 KDR KDR TEK TEK EPHA3 EPHA3 FLT4 FLT4 EGFR EGFR SRC SRC FGFR1 FGFR1 PDGFRB PDGFRB TNK2 TNK2 EPHB3 EPHB3 NTRK1 NTRK1 PTK2 PTK2 DDR2 DDR2 ERBB4 ERBB4 PTK6 PTK6 ABL2 ABL2 ABL1 ABL1 FGFR2 FGFR2 JAK3 JAK3 FLT1 FLT1 AXL AXL YES1 YES1 FGFR3 FGFR3 EPHA7 EPHA7 KIT KIT NTRK3 NTRK3 INSR INSR MUSK MUSK BMX BMX EPHA1 EPHA1 DDR1 DDR1 JAK2 JAK2 CSK CSK EPHA5 EPHA5 CSF1R CSF1R LTK LTK TYRO3 TYRO3 PTK2B PTK2B FLT3 FLT3 TXK TXK TEC TEC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ITKTyrosine-protein kinase. (620 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa)
LCKTyrosine-protein kinase. (539 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
F7HFW4_CALJAUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (852 aa)
MAP3K11Mitogen-activated protein kinase kinase kinase. (847 aa)
EPHB1EPH receptor B1. (1055 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa)
BLKTyrosine-protein kinase. (464 aa)
ROS1Tyrosine-protein kinase receptor. (2347 aa)
MST1RMacrophage stimulating 1 receptor. (1399 aa)
FRKTyrosine-protein kinase. (505 aa)
BTKTyrosine-protein kinase. (659 aa)
FYNTyrosine-protein kinase. (537 aa)
METHepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1353 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1075 aa)
SYKUncharacterized protein. (636 aa)
EPHB2EPH receptor B2. (987 aa)
EPHA8EPH receptor A8. (1005 aa)
INSRRTyrosine-protein kinase receptor. (1301 aa)
IGF1RTyrosine-protein kinase receptor. (1366 aa)
TYK2Tyrosine-protein kinase. (1190 aa)
FGFR4Fibroblast growth factor receptor. (801 aa)
EPHA2EPH receptor A2. (976 aa)
EPHA6EPH receptor A6. (1129 aa)
ALKTyrosine-protein kinase receptor. (1621 aa)
FGRTyrosine-protein kinase. (528 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (821 aa)
SRMSTyrosine-protein kinase. (480 aa)
ZAP70Zeta chain of T cell receptor associated protein kinase 70. (648 aa)
ERBB3Receptor tyrosine-protein kinase erbB-3 isoform 1. (1341 aa)
EPHA4Ephrin type-A receptor 4. (986 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase. (955 aa)
MAP3K9Uncharacterized protein. (1119 aa)
EPHB4Ephrin type-B receptor 4. (987 aa)
MATKTyrosine-protein kinase. (508 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1115 aa)
TNK1Tyrosine kinase non receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (666 aa)
MERTKMER proto-oncogene, tyrosine kinase. (994 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa)
LYNTyrosine-protein kinase. (491 aa)
JAK1Tyrosine-protein kinase. (1154 aa)
MAP3K21Mitogen-activated protein kinase kinase kinase. (1039 aa)
KDRVascular endothelial growth factor receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
TEKTEK receptor tyrosine kinase. (1074 aa)
EPHA3Ephrin type-A receptor 3 isoform a. (984 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1366 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
SRCTyrosine-protein kinase. (553 aa)
FGFR1Fibroblast growth factor receptor. (885 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1108 aa)
TNK2Tyrosine kinase non receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1118 aa)
EPHB3EPH receptor B3. (1013 aa)
NTRK1Tyrosine-protein kinase receptor. (795 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1137 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (868 aa)
ERBB4Receptor protein-tyrosine kinase. (1331 aa)
PTK6Tyrosine-protein kinase. (476 aa)
ABL2Tyrosine-protein kinase. (1183 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
FGFR2Fibroblast growth factor receptor. (822 aa)
JAK3Tyrosine-protein kinase. (1117 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1337 aa)
AXLAXL receptor tyrosine kinase. (896 aa)
YES1Tyrosine-protein kinase. (548 aa)
FGFR3Fibroblast growth factor receptor. (810 aa)
EPHA7Ephrin type-A receptor 7. (998 aa)
KITMast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (976 aa)
NTRK3Tyrosine-protein kinase receptor. (864 aa)
INSRTyrosine-protein kinase receptor. (1382 aa)
MUSKMuscle associated receptor tyrosine kinase. (881 aa)
BMXTyrosine-protein kinase. (679 aa)
EPHA1EPH receptor A1. (987 aa)
DDR1Discoidin domain receptor tyrosine kinase 1. (913 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
CSKTyrosine-protein kinase. (450 aa)
EPHA5Ephrin type-A receptor 5 isoform a. (1038 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (961 aa)
LTKTyrosine-protein kinase receptor. (863 aa)
TYRO3Tyrosine-protein kinase receptor TYRO3. (890 aa)
PTK2BProtein-tyrosine kinase 2-beta isoform a; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
FLT3Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (993 aa)
TXKTyrosine-protein kinase. (600 aa)
TECTyrosine-protein kinase. (631 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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