(45 nodes) c4 zinc finger in nuclear hormone receptors network (Callithrix jacchus)

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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Predicted Interactions

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Your Input:
	RORB	RAR related orphan receptor B. (470 aa)
	NR3C2	Uncharacterized protein. (987 aa)
	NR2C2	Nuclear receptor subfamily 2 group C member 2. (648 aa)
	NR2C1	Nuclear receptor subfamily 2 group C member 1. (604 aa)
	AR	Androgen receptor. (887 aa)
	THRB	Uncharacterized protein. (476 aa)
	RARB	Retinoic acid receptor beta isoform 1. (448 aa)
	RORA	RAR related orphan receptor A. (486 aa)
	NR1H2	Nuclear receptor subfamily 1 group H member 2. (527 aa)
	RXRG	Retinoic acid receptor RXR-gamma isoform a. (463 aa)
	NR5A2	Nuclear receptor subfamily 5 group A member 2. (541 aa)
	NR6A1	Nuclear receptor subfamily 6 group A member 1. (480 aa)
	NR1I2	Nuclear receptor subfamily 1 group I member 2. (472 aa)
	NR4A3	Nuclear receptor subfamily 4 group A member 3. (712 aa)
	RARA	Uncharacterized protein. (468 aa)
	VDR	Vitamin D receptor. (427 aa)
	ESRRG	Estrogen related receptor gamma. (469 aa)
	NR1D1	Nuclear receptor subfamily 1 group D member 1. (614 aa)
	HNF4A	Hepatocyte nuclear factor 4 alpha. (474 aa)
	NR4A1	Nuclear receptor subfamily 4 group A member 1. (826 aa)
	ESRRA	Steroid hormone receptor ERR1. (422 aa)
	NR3C1	Glucocorticoid receptor; Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP [...] (778 aa)
	NR2E3	Nuclear receptor subfamily 2 group E member 3. (408 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
	ESR2	Estrogen receptor beta; Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1 (ER-alpha), and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. May play a role in ovarian follicular growth and maturation. (530 aa)
	RXRB	Retinoid X receptor beta. (537 aa)
	NR2E1	Nuclear receptor subfamily 2 group E member 1. (421 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
	HNF4G	Uncharacterized protein. (461 aa)
	PPARD	Peroxisome proliferator-activated receptor delta isoform 1. (441 aa)
	RARG	Retinoic acid receptor gamma isoform 1. (454 aa)
	PPARA	Peroxisome proliferator-activated receptor alpha. (468 aa)
	RXRA	Retinoid X receptor alpha. (492 aa)
	NR1D2	Nuclear receptor subfamily 1 group D member 2 isoform 1. (579 aa)
	NR5A1	Nuclear receptor subfamily 5 group A member 1. (461 aa)
	NR2F1	Nuclear receptor subfamily 2 group F member 1. (423 aa)
	THRA	Thyroid hormone receptor alpha isoform 2. (490 aa)
	NR4A2	Nuclear receptor subfamily 4 group A member 2. (598 aa)
	NR1H4	Nuclear receptor subfamily 1 group H member 4. (486 aa)
	NR1I3	Nuclear receptor subfamily 1 group I member 3. (348 aa)
	ESRRB	Estrogen related receptor beta. (454 aa)
	NR2F2	Nuclear receptor subfamily 2 group F member 2. (394 aa)
	NR1H3	Nuclear receptor subfamily 1 group H member 3. (466 aa)
	NR2F6	Nuclear receptor subfamily 2 group F member 6. (493 aa)
	PGR	Progesterone receptor. (935 aa)

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AR	ESR1	ENSCJAP00000006494	ENSCJAP00000036232	Androgen receptor.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.767
AR	ESR2	ENSCJAP00000006494	ENSCJAP00000036235	Androgen receptor.	Estrogen receptor beta; Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1 (ER-alpha), and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. May play a role in ovarian follicular growth and maturation.	0.553
AR	NR3C1	ENSCJAP00000006494	ENSCJAP00000033976	Androgen receptor.	Glucocorticoid receptor; Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP [...]	0.658
AR	NR3C2	ENSCJAP00000006494	ENSCJAP00000004277	Androgen receptor.	Uncharacterized protein.	0.655
AR	PGR	ENSCJAP00000006494	ENSCJAP00000001019	Androgen receptor.	Progesterone receptor.	0.680
ESR1	AR	ENSCJAP00000036232	ENSCJAP00000006494	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Androgen receptor.	0.767
ESR1	ESR2	ENSCJAP00000036232	ENSCJAP00000036235	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Estrogen receptor beta; Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1 (ER-alpha), and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. May play a role in ovarian follicular growth and maturation.	0.995
ESR1	ESRRA	ENSCJAP00000036232	ENSCJAP00000033307	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Steroid hormone receptor ERR1.	0.461
ESR1	NR3C1	ENSCJAP00000036232	ENSCJAP00000033976	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Glucocorticoid receptor; Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP [...]	0.538
ESR1	NR5A1	ENSCJAP00000036232	ENSCJAP00000053577	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Nuclear receptor subfamily 5 group A member 1.	0.570
ESR1	NR5A2	ENSCJAP00000036232	ENSCJAP00000009284	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Nuclear receptor subfamily 5 group A member 2.	0.501
ESR1	PGR	ENSCJAP00000036232	ENSCJAP00000001019	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Progesterone receptor.	0.962
ESR1	PPARG	ENSCJAP00000036232	ENSCJAP00000048822	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.564
ESR2	AR	ENSCJAP00000036235	ENSCJAP00000006494	Estrogen receptor beta; Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1 (ER-alpha), and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. May play a role in ovarian follicular growth and maturation.	Androgen receptor.	0.553
ESR2	ESR1	ENSCJAP00000036235	ENSCJAP00000036232	Estrogen receptor beta; Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1 (ER-alpha), and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. May play a role in ovarian follicular growth and maturation.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.995
ESR2	NR3C1	ENSCJAP00000036235	ENSCJAP00000033976	Estrogen receptor beta; Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1 (ER-alpha), and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. May play a role in ovarian follicular growth and maturation.	Glucocorticoid receptor; Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP [...]	0.401
ESR2	NR5A1	ENSCJAP00000036235	ENSCJAP00000053577	Estrogen receptor beta; Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1 (ER-alpha), and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. May play a role in ovarian follicular growth and maturation.	Nuclear receptor subfamily 5 group A member 1.	0.506
ESR2	NR5A2	ENSCJAP00000036235	ENSCJAP00000009284	Estrogen receptor beta; Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1 (ER-alpha), and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. May play a role in ovarian follicular growth and maturation.	Nuclear receptor subfamily 5 group A member 2.	0.457
ESR2	PGR	ENSCJAP00000036235	ENSCJAP00000001019	Estrogen receptor beta; Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1 (ER-alpha), and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. May play a role in ovarian follicular growth and maturation.	Progesterone receptor.	0.877
ESRRA	ESR1	ENSCJAP00000033307	ENSCJAP00000036232	Steroid hormone receptor ERR1.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.461