STRINGSTRING
RPS6KB2 RPS6KB2 ADCY7 ADCY7 MTOR MTOR HSPA1A HSPA1A HSPA6 HSPA6 RPTOR RPTOR AKT1S1 AKT1S1 ADCY8 ADCY8 FOXA2 FOXA2 FOXO3 FOXO3 ATG5 ATG5 IGF1R IGF1R ADCY4 ADCY4 PRKAA1 PRKAA1 HSPA8 HSPA8 ADCY5 ADCY5 ADCY3 ADCY3 ADCY2 ADCY2 SOD1 SOD1 SOD2 SOD2 NRAS NRAS PIK3CA PIK3CA PIK3R2 PIK3R2 AKT2 AKT2 PRKAA2 PRKAA2 PIK3R1 PIK3R1 AKT3 AKT3 INS INS PRKAG2 PRKAG2 ADCY6 ADCY6 PRKAG1 PRKAG1 PIK3R3 PIK3R3 SIRT1 SIRT1 PRKACB PRKACB PRKAB1 PRKAB1 RPS6KB1 RPS6KB1 CLPB CLPB ADCY9 ADCY9 PIK3CB PIK3CB INSR INSR CRYAB CRYAB HSPA1L HSPA1L IGF1 IGF1 PRKACA PRKACA HRAS HRAS LOC100408115 LOC100408115 FOXO1 FOXO1 AKT1 AKT1 IRS1 IRS1 PRKAG3 PRKAG3 HDAC2 HDAC2 IRS4 IRS4 PRKACG PRKACG EIF4EBP2 EIF4EBP2 HSPA2 HSPA2 HDAC1 HDAC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1079 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
HSPA1AUncharacterized protein; Belongs to the heat shock protein 70 family. (615 aa)
HSPA6Heat shock protein family A (Hsp70) member 6; Belongs to the heat shock protein 70 family. (641 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1335 aa)
AKT1S1Proline-rich AKT1 substrate 1 isoform a. (276 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1252 aa)
FOXA2Forkhead box A2. (456 aa)
FOXO3Forkhead box protein O3. (672 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
IGF1RTyrosine-protein kinase receptor. (1366 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
HSPA8Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (537 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1261 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
SOD2Superoxide dismutase [Mn], mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (318 aa)
NRASGTPase NRas. (189 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (727 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 1. (724 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
INSInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (108 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (569 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1168 aa)
PRKAG1Uncharacterized protein. (340 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
SIRT1Sirtuin 1. (753 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily. (398 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
CLPBClpB homolog, mitochondrial AAA ATPase chaperonin. (712 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform 1; Belongs to the PI3/PI4-kinase family. (1070 aa)
INSRTyrosine-protein kinase receptor. (1382 aa)
CRYABSHSP domain-containing protein; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (175 aa)
HSPA1LHeat shock protein family A (Hsp70) member 1 like; Belongs to the heat shock protein 70 family. (641 aa)
IGF1Insulin like growth factor 1. (197 aa)
PRKACAcAMP-dependent protein kinase catalytic subunit alpha isoform 1; Belongs to the protein kinase superfamily. (351 aa)
HRASHRas proto-oncogene, GTPase. (209 aa)
LOC100408115Uncharacterized protein; Belongs to the protein kinase superfamily. (387 aa)
FOXO1Fork-head domain-containing protein. (654 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (459 aa)
IRS1Insulin receptor substrate 1. (1254 aa)
PRKAG3Protein kinase AMP-activated non-catalytic subunit gamma 3. (571 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (491 aa)
IRS4Insulin receptor substrate 4. (1255 aa)
PRKACGUncharacterized protein; Belongs to the protein kinase superfamily. (360 aa)
EIF4EBP2Eukaryotic translation initiation factor 4E binding protein 2. (121 aa)
HSPA2Heat shock-related 70 kDa protein 2; Belongs to the heat shock protein 70 family. (641 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (540 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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