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PPARA | Peroxisome proliferator-activated receptor alpha. (468 aa) | ||||
ADIPOR2 | Adiponectin receptor protein 2. (386 aa) | ||||
NDUFV1 | NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (464 aa) | ||||
COX6A2 | Cytochrome c oxidase subunit 6A, mitochondrial. (136 aa) | ||||
LOC100388954 | Cytochrome c oxidase subunit 6A, mitochondrial. (108 aa) | ||||
LOC100395443 | Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (274 aa) | ||||
MAP3K11 | Mitogen-activated protein kinase kinase kinase. (847 aa) | ||||
ATF4 | Activating transcription factor 4. (351 aa) | ||||
NDUFA9 | NADH:ubiquinone oxidoreductase subunit A9. (377 aa) | ||||
UQCRC1 | Ubiquinol-cytochrome c reductase core protein 1. (491 aa) | ||||
BCL2L11 | BCL2 like 11. (249 aa) | ||||
NDUFB3 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3. (98 aa) | ||||
NDUFB7 | NADH:ubiquinone oxidoreductase subunit B7. (138 aa) | ||||
CYP2E1 | Uncharacterized protein; Belongs to the cytochrome P450 family. (528 aa) | ||||
MLX | MAX dimerization protein MLX. (298 aa) | ||||
NDUFS2 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial isoform 1; Belongs to the complex I 49 kDa subunit family. (463 aa) | ||||
NDUFA13 | Uncharacterized protein. (151 aa) | ||||
CASP3 | Caspase 3; Belongs to the peptidase C14A family. (284 aa) | ||||
ADIPOR1 | Adiponectin receptor protein 1. (375 aa) | ||||
PRKAA1 | Non-specific serine/threonine protein kinase. (574 aa) | ||||
IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta isoform 1. (756 aa) | ||||
SDHB | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa) | ||||
MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1481 aa) | ||||
NDUFB4 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 isoform 1. (128 aa) | ||||
LOC100389097 | Cytochrome b-c1 complex subunit 2, mitochondrial. (453 aa) | ||||
FASLG | Fas ligand; Belongs to the tumor necrosis factor family. (280 aa) | ||||
LOC100390127 | Cytochrome c oxidase subunit; Belongs to the cytochrome c oxidase subunit 6B. (86 aa) | ||||
MAPK9 | Mitogen-activated protein kinase. (441 aa) | ||||
NDUFA7 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7. (113 aa) | ||||
SDHD | Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (159 aa) | ||||
COX7C | Cytochrome c oxidase subunit 7C. (63 aa) | ||||
NDUFB5 | Uncharacterized protein. (189 aa) | ||||
UQCRQ | Ubiquinol-cytochrome c reductase complex III subunit VII. (82 aa) | ||||
PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) | ||||
NDUFB2 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial. (105 aa) | ||||
H9KX01_CALJA | Uncharacterized protein. (114 aa) | ||||
MAPK8 | Mitogen-activated protein kinase. (450 aa) | ||||
PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta. (727 aa) | ||||
AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) | ||||
EIF2S1 | Eukaryotic translation initiation factor 2 subunit alpha. (315 aa) | ||||
NFKB1 | Nuclear factor kappa B subunit 1. (998 aa) | ||||
NDUFS8 | Uncharacterized protein. (210 aa) | ||||
NDUFV3 | NADH:ubiquinone oxidoreductase subunit V3. (472 aa) | ||||
PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) | ||||
PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 1. (724 aa) | ||||
IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa) | ||||
IL1A | Interleukin-1; Belongs to the IL-1 family. (272 aa) | ||||
LEPR | Leptin receptor. (1165 aa) | ||||
AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) | ||||
BID | BH3-interacting domain death agonist; Counters the protective effect of Bcl-2. (192 aa) | ||||
NDUFB8 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (186 aa) | ||||
LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) | ||||
ITCH | E3 ubiquitin-protein ligase. (864 aa) | ||||
INS | Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (108 aa) | ||||
NDUFA3 | Uncharacterized protein. (84 aa) | ||||
COX7B2 | Cytochrome c oxidase subunit 7B2. (81 aa) | ||||
XBP1 | BZIP domain-containing protein. (371 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) | ||||
NDUFS3 | NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (262 aa) | ||||
MLXIP | MLX-interacting protein. (919 aa) | ||||
PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (569 aa) | ||||
NDUFAB1 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (156 aa) | ||||
PRKAG1 | Uncharacterized protein. (340 aa) | ||||
PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa) | ||||
LOC100406481 | Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (91 aa) | ||||
CYC1 | Cytochrome c1, heme protein, mitochondrial. (325 aa) | ||||
SOCS3 | Suppressor of cytokine signaling 3. (225 aa) | ||||
LOC100407930 | Uncharacterized protein. (116 aa) | ||||
LOC100895863 | Cytochrome b-c1 complex subunit 10. (56 aa) | ||||
NDUFB9 | NADH:ubiquinone oxidoreductase subunit B9; Belongs to the complex I LYR family. (185 aa) | ||||
COX7A1 | Uncharacterized protein. (80 aa) | ||||
SREBF1 | Sterol regulatory element binding transcription factor 1. (1178 aa) | ||||
DDIT3 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa) | ||||
UQCRB | Ubiquinol-cytochrome c reductase binding protein. (161 aa) | ||||
GSK3A | Glycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (483 aa) | ||||
IL6 | Interleukin 6. (212 aa) | ||||
PKLR | Pyruvate kinase; Belongs to the pyruvate kinase family. (574 aa) | ||||
PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa) | ||||
EIF2AK3 | Eukaryotic translation initiation factor 2-alpha kinase 3. (1117 aa) | ||||
GSK3B | Glycogen synthase kinase-3 beta isoform 1; Belongs to the protein kinase superfamily. (433 aa) | ||||
PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform isoform 1; Belongs to the PI3/PI4-kinase family. (1070 aa) | ||||
TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (232 aa) | ||||
RXRA | Retinoid X receptor alpha. (492 aa) | ||||
IL6R | Uncharacterized protein. (468 aa) | ||||
INSR | Tyrosine-protein kinase receptor. (1382 aa) | ||||
LOC108591148 | Uncharacterized protein. (82 aa) | ||||
COX8A | Cytochrome c oxidase subunit 8A. (69 aa) | ||||
LOC100413276 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
NDUFC1 | NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial. (76 aa) | ||||
NDUFB1 | Uncharacterized protein. (59 aa) | ||||
COX4I1 | Cytochrome c oxidase subunit 4I1. (169 aa) | ||||
ENSCJAP00000056951 | Uncharacterized protein. (82 aa) | ||||
COX5A | Uncharacterized protein. (150 aa) | ||||
NDUFA10 | NADH:ubiquinone oxidoreductase subunit A10. (272 aa) | ||||
NDUFV2 | NADH:ubiquinone oxidoreductase core subunit V2. (249 aa) | ||||
NDUFS7 | Oxidored_q6 domain-containing protein; Belongs to the complex I 20 kDa subunit family. (142 aa) | ||||
NDUFA2 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (99 aa) | ||||
NDUFB10 | NADH:ubiquinone oxidoreductase subunit B10. (178 aa) | ||||
NDUFA5 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5. (116 aa) | ||||
LOC100406761 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
LOC103793463 | Uncharacterized protein. (151 aa) | ||||
ENSCJAP00000059748 | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (195 aa) | ||||
NDUFA1 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1. (70 aa) | ||||
LOC108593294 | Uncharacterized protein. (70 aa) | ||||
COX4I2 | Cytochrome c oxidase subunit 4 isoform 2, mitochondrial. (171 aa) | ||||
LOC100401718 | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) | ||||
NDUFS5 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 5. (106 aa) | ||||
BAX | BCL2 associated X, apoptosis regulator. (193 aa) | ||||
NDUFA4 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4. (82 aa) | ||||
NDUFA6 | NADH:ubiquinone oxidoreductase subunit A6; Belongs to the complex I LYR family. (154 aa) | ||||
CDC42 | Cell division control protein 42 homolog isoform 1. (191 aa) | ||||
LOC108593648 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) | ||||
JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa) | ||||
MAPK10 | Mitogen-activated protein kinase. (552 aa) | ||||
SDHA | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (664 aa) | ||||
LOC100407794 | Uncharacterized protein. (63 aa) | ||||
COX8C | Cytochrome c oxidase subunit 8C. (72 aa) | ||||
NDUFA4L2 | NDUFA4 mitochondrial complex associated like 2. (87 aa) | ||||
LOC108587827 | Uncharacterized protein. (63 aa) | ||||
NDUFS1 | NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (741 aa) | ||||
NDUFS6 | zf-CHCC domain-containing protein. (252 aa) | ||||
NDUFA8 | NADH:ubiquinone oxidoreductase subunit A8. (244 aa) | ||||
CASP7 | Caspase 7; Belongs to the peptidase C14A family. (303 aa) | ||||
NDUFS4 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial. (175 aa) | ||||
NDUFA12 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (145 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (459 aa) | ||||
IRS1 | Insulin receptor substrate 1. (1254 aa) | ||||
ENSCJAP00000072771 | Uncharacterized protein. (207 aa) | ||||
LOC100401813 | Uncharacterized protein. (204 aa) | ||||
PRKAG3 | Protein kinase AMP-activated non-catalytic subunit gamma 3. (571 aa) | ||||
FOS | Proto-oncogene c-Fos. (380 aa) | ||||
COX7B | Cytochrome c oxidase subunit 7B. (84 aa) | ||||
TNFRSF1A | TNF receptor superfamily member 1A. (508 aa) | ||||
COX6B2 | Uncharacterized protein. (94 aa) | ||||
CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) | ||||
ENSCJAP00000074289 | Uncharacterized protein. (128 aa) | ||||
RELA | RELA proto-oncogene, NF-kB subunit. (571 aa) | ||||
ADIPOQ | Adiponectin, C1Q and collagen domain containing. (299 aa) | ||||
TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) | ||||
ENSCJAP00000075971 | Uncharacterized protein. (120 aa) | ||||
FAS | Fas cell surface death receptor. (454 aa) | ||||
NDUFC2 | NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (126 aa) |