Atypical chemokine receptor 1 (Duffy blood group).

C-C motif chemokine.

Atypical chemokine receptor 1 (Duffy blood group).

Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family.

Atypical chemokine receptor 1 (Duffy blood group).

Glycophorin.

Atypical chemokine receptor 1 (Duffy blood group).

Glycophorin C (Gerbich blood group).

C-C motif chemokine.

Atypical chemokine receptor 1 (Duffy blood group).

C-C motif chemokine.

CD36 molecule; Belongs to the CD36 family.

C-C motif chemokine.

Tumor necrosis factor receptor superfamily member 5; Receptor for TNFSF5/CD40LG (By similarity). Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).

C-C motif chemokine.

CD40 ligand, membrane form; Cytokine that acts as a ligand to CD40/TNFRSF5 (By similarity). Costimulates T-cell proliferation and cytokine production (By similarity). Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation (By similarity). Induces the activation of NF-kappa-B (By similarity). Induces the activation of kinases MAPK8 and PAK2 in T-cells (By similarity). Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of [...]

C-C motif chemokine.

Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family.

C-C motif chemokine.

Hepatocyte growth factor; Belongs to the peptidase S1 family.

C-C motif chemokine.

Intercellular adhesion molecule 1.

C-C motif chemokine.

Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons; Belongs to the type II (or gamma) interferon family.

C-C motif chemokine.

Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...]

C-C motif chemokine.

Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family.

C-C motif chemokine.

Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.

C-C motif chemokine.

Interleukin 6.

C-C motif chemokine.

Integrin beta.

C-C motif chemokine.

Uncharacterized protein.

C-C motif chemokine.

Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.

C-C motif chemokine.

Platelet and endothelial cell adhesion molecule 1.