(12 nodes) HDR through Single Strand Annealing (SSA), and Endodeoxyribonuclease activity network (Vavraia culicis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	VCUG_02307	Uncharacterized protein. (558 aa)
	VCUG_02128	OB domain-containing protein. (284 aa)
	VCUG_02378	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (955 aa)
	VCUG_02284	Uncharacterized protein. (1034 aa)
	VCUG_02157	Atypical/PIKK/ATR protein kinase; Belongs to the PI3/PI4-kinase family. (2290 aa)
	VCUG_01589	AAA_15 domain-containing protein. (1215 aa)
	VCUG_01731	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (574 aa)
	VCUG_01375	Helicase ATP-binding domain-containing protein. (745 aa)
	VCUG_00409	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (612 aa)
	VCUG_00424	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (849 aa)
	VCUG_00230	Recombination protein rad52. (261 aa)
	VCUG_00047	ERCC4 domain-containing protein. (476 aa)

Your Current Organism:

Vavraia culicis

NCBI taxonomy Id: 948595
Other names: V. culicis subsp. floridensis, Vavraia culicis subsp. floridensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
VCUG_00047	VCUG_00230	L2GYU4	L2GX22	ERCC4 domain-containing protein.	Recombination protein rad52.	0.854
VCUG_00047	VCUG_00409	L2GYU4	L2GWW7	ERCC4 domain-containing protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.886
VCUG_00047	VCUG_00424	L2GYU4	L2GWY2	ERCC4 domain-containing protein.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.978
VCUG_00047	VCUG_01375	L2GYU4	L2GUQ6	ERCC4 domain-containing protein.	Helicase ATP-binding domain-containing protein.	0.450
VCUG_00047	VCUG_01589	L2GYU4	L2GTC1	ERCC4 domain-containing protein.	AAA_15 domain-containing protein.	0.650
VCUG_00047	VCUG_01731	L2GYU4	L2GTT4	ERCC4 domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.739
VCUG_00047	VCUG_02128	L2GYU4	L2GRX5	ERCC4 domain-containing protein.	OB domain-containing protein.	0.684
VCUG_00047	VCUG_02157	L2GYU4	L2GSL7	ERCC4 domain-containing protein.	Atypical/PIKK/ATR protein kinase; Belongs to the PI3/PI4-kinase family.	0.827
VCUG_00047	VCUG_02284	L2GYU4	L2GSG6	ERCC4 domain-containing protein.	Uncharacterized protein.	0.784
VCUG_00047	VCUG_02307	L2GYU4	L2GRA9	ERCC4 domain-containing protein.	Uncharacterized protein.	0.808
VCUG_00047	VCUG_02378	L2GYU4	L2GS59	ERCC4 domain-containing protein.	ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.	0.983
VCUG_00230	VCUG_00047	L2GX22	L2GYU4	Recombination protein rad52.	ERCC4 domain-containing protein.	0.854
VCUG_00230	VCUG_00409	L2GX22	L2GWW7	Recombination protein rad52.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.992
VCUG_00230	VCUG_00424	L2GX22	L2GWY2	Recombination protein rad52.	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	0.787
VCUG_00230	VCUG_01375	L2GX22	L2GUQ6	Recombination protein rad52.	Helicase ATP-binding domain-containing protein.	0.548
VCUG_00230	VCUG_01589	L2GX22	L2GTC1	Recombination protein rad52.	AAA_15 domain-containing protein.	0.890
VCUG_00230	VCUG_01731	L2GX22	L2GTT4	Recombination protein rad52.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.791
VCUG_00230	VCUG_02128	L2GX22	L2GRX5	Recombination protein rad52.	OB domain-containing protein.	0.947
VCUG_00230	VCUG_02157	L2GX22	L2GSL7	Recombination protein rad52.	Atypical/PIKK/ATR protein kinase; Belongs to the PI3/PI4-kinase family.	0.803
VCUG_00230	VCUG_02284	L2GX22	L2GSG6	Recombination protein rad52.	Uncharacterized protein.	0.831