(20 nodes) Iron-sulfur cluster assembly network (Cebus capucinus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	FXN	Uncharacterized protein. (213 aa)
	LOC108298748	Uncharacterized protein. (286 aa)
	CIAPIN1	Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] (312 aa)
	CIAPIN1-2	Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] (274 aa)
	LYRM4	Uncharacterized protein; Belongs to the complex I LYR family. (96 aa)
	NDOR1	NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (608 aa)
	ISCA1	Fe-S_biosyn domain-containing protein. (129 aa)
	SCLY	Selenocysteine lyase. (447 aa)
	NFS1	Aminotran_5 domain-containing protein. (457 aa)
	NFU1	NFU1 iron-sulfur cluster scaffold. (254 aa)
	ISCA2	Fe-S_biosyn domain-containing protein. (154 aa)
	BOLA2B	Uncharacterized protein; Belongs to the BolA/IbaG family. (152 aa)
	GLRX3	Uncharacterized protein. (335 aa)
	MOCOS	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. (849 aa)
	BOLA3	BolA family member 3; Belongs to the BolA/IbaG family. (121 aa)
	ENSCCAP00000032157	Uncharacterized protein; Belongs to the complex I LYR family. (101 aa)
	ENSCCAP00000032585	Uncharacterized protein. (144 aa)
	LOC108314347	Uncharacterized protein. (299 aa)
	GLRX5	Glutaredoxin 5. (157 aa)
	ISCU	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (167 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BOLA2B	BOLA3	ENSCCAP00000024190	ENSCCAP00000031743	Uncharacterized protein; Belongs to the BolA/IbaG family.	BolA family member 3; Belongs to the BolA/IbaG family.	0.615
BOLA2B	CIAPIN1	ENSCCAP00000024190	ENSCCAP00000002428	Uncharacterized protein; Belongs to the BolA/IbaG family.	Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...]	0.779
BOLA2B	CIAPIN1-2	ENSCCAP00000024190	ENSCCAP00000005440	Uncharacterized protein; Belongs to the BolA/IbaG family.	Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...]	0.779
BOLA2B	GLRX3	ENSCCAP00000024190	ENSCCAP00000029586	Uncharacterized protein; Belongs to the BolA/IbaG family.	Uncharacterized protein.	0.912
BOLA2B	ISCA1	ENSCCAP00000024190	ENSCCAP00000012397	Uncharacterized protein; Belongs to the BolA/IbaG family.	Fe-S_biosyn domain-containing protein.	0.511
BOLA2B	ISCA2	ENSCCAP00000024190	ENSCCAP00000024014	Uncharacterized protein; Belongs to the BolA/IbaG family.	Fe-S_biosyn domain-containing protein.	0.545
BOLA2B	ISCU	ENSCCAP00000024190	ENSCCAP00000038719	Uncharacterized protein; Belongs to the BolA/IbaG family.	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.510
BOLA2B	LOC108298748	ENSCCAP00000024190	ENSCCAP00000001875	Uncharacterized protein; Belongs to the BolA/IbaG family.	Uncharacterized protein.	0.912
BOLA2B	LOC108314347	ENSCCAP00000024190	ENSCCAP00000032885	Uncharacterized protein; Belongs to the BolA/IbaG family.	Uncharacterized protein.	0.912
BOLA2B	NDOR1	ENSCCAP00000024190	ENSCCAP00000011554	Uncharacterized protein; Belongs to the BolA/IbaG family.	NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.468
BOLA2B	NFU1	ENSCCAP00000024190	ENSCCAP00000023664	Uncharacterized protein; Belongs to the BolA/IbaG family.	NFU1 iron-sulfur cluster scaffold.	0.543
BOLA3	BOLA2B	ENSCCAP00000031743	ENSCCAP00000024190	BolA family member 3; Belongs to the BolA/IbaG family.	Uncharacterized protein; Belongs to the BolA/IbaG family.	0.615
BOLA3	CIAPIN1	ENSCCAP00000031743	ENSCCAP00000002428	BolA family member 3; Belongs to the BolA/IbaG family.	Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...]	0.744
BOLA3	CIAPIN1-2	ENSCCAP00000031743	ENSCCAP00000005440	BolA family member 3; Belongs to the BolA/IbaG family.	Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...]	0.744
BOLA3	GLRX3	ENSCCAP00000031743	ENSCCAP00000029586	BolA family member 3; Belongs to the BolA/IbaG family.	Uncharacterized protein.	0.881
BOLA3	GLRX5	ENSCCAP00000031743	ENSCCAP00000035308	BolA family member 3; Belongs to the BolA/IbaG family.	Glutaredoxin 5.	0.946
BOLA3	ISCA1	ENSCCAP00000031743	ENSCCAP00000012397	BolA family member 3; Belongs to the BolA/IbaG family.	Fe-S_biosyn domain-containing protein.	0.536
BOLA3	ISCA2	ENSCCAP00000031743	ENSCCAP00000024014	BolA family member 3; Belongs to the BolA/IbaG family.	Fe-S_biosyn domain-containing protein.	0.586
BOLA3	ISCU	ENSCCAP00000031743	ENSCCAP00000038719	BolA family member 3; Belongs to the BolA/IbaG family.	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.510
BOLA3	LOC108298748	ENSCCAP00000031743	ENSCCAP00000001875	BolA family member 3; Belongs to the BolA/IbaG family.	Uncharacterized protein.	0.881