(13 nodes) Autophagy, and Autophagy-related protein 16 network (Cebus capucinus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ATG16L1	Autophagy related 16 like 1. (624 aa)
	MAP1LC3C	Microtubule associated protein 1 light chain 3 gamma. (147 aa)
	ATG3	Autophagy-related protein 3. (307 aa)
	ATG12	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	LOC108310106	Autophagy-related protein 3. (302 aa)
	GABARAP	GABA type A receptor-associated protein. (117 aa)
	MAP1LC3A	Microtubule associated protein 1 light chain 3 alpha. (122 aa)
	GABARAPL1	GABA type A receptor associated protein like 1. (146 aa)
	ENSCCAP00000028878	Uncharacterized protein. (111 aa)
	SQSTM1	Sequestosome 1. (439 aa)
	ATG7	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (707 aa)
	NBR1	NBR1 autophagy cargo receptor. (960 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG12	ATG16L1	ENSCCAP00000008954	ENSCCAP00000001350	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy related 16 like 1.	0.999
ATG12	ATG3	ENSCCAP00000008954	ENSCCAP00000006334	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy-related protein 3.	0.990
ATG12	ATG5	ENSCCAP00000008954	ENSCCAP00000009149	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
ATG12	ATG7	ENSCCAP00000008954	ENSCCAP00000034593	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.996
ATG12	ENSCCAP00000028878	ENSCCAP00000008954	ENSCCAP00000028878	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Uncharacterized protein.	0.752
ATG12	GABARAP	ENSCCAP00000008954	ENSCCAP00000016611	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	GABA type A receptor-associated protein.	0.982
ATG12	GABARAPL1	ENSCCAP00000008954	ENSCCAP00000026805	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	GABA type A receptor associated protein like 1.	0.982
ATG12	LOC108310106	ENSCCAP00000008954	ENSCCAP00000016596	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Autophagy-related protein 3.	0.990
ATG12	MAP1LC3A	ENSCCAP00000008954	ENSCCAP00000018120	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Microtubule associated protein 1 light chain 3 alpha.	0.824
ATG12	MAP1LC3C	ENSCCAP00000008954	ENSCCAP00000002626	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Microtubule associated protein 1 light chain 3 gamma.	0.836
ATG12	NBR1	ENSCCAP00000008954	ENSCCAP00000038537	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	NBR1 autophagy cargo receptor.	0.819
ATG12	SQSTM1	ENSCCAP00000008954	ENSCCAP00000032336	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	Sequestosome 1.	0.846
ATG16L1	ATG12	ENSCCAP00000001350	ENSCCAP00000008954	Autophagy related 16 like 1.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.999
ATG16L1	ATG3	ENSCCAP00000001350	ENSCCAP00000006334	Autophagy related 16 like 1.	Autophagy-related protein 3.	0.979
ATG16L1	ATG5	ENSCCAP00000001350	ENSCCAP00000009149	Autophagy related 16 like 1.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.999
ATG16L1	ATG7	ENSCCAP00000001350	ENSCCAP00000034593	Autophagy related 16 like 1.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.830
ATG16L1	ENSCCAP00000028878	ENSCCAP00000001350	ENSCCAP00000028878	Autophagy related 16 like 1.	Uncharacterized protein.	0.604
ATG16L1	GABARAP	ENSCCAP00000001350	ENSCCAP00000016611	Autophagy related 16 like 1.	GABA type A receptor-associated protein.	0.963
ATG16L1	GABARAPL1	ENSCCAP00000001350	ENSCCAP00000026805	Autophagy related 16 like 1.	GABA type A receptor associated protein like 1.	0.970
ATG16L1	LOC108310106	ENSCCAP00000001350	ENSCCAP00000016596	Autophagy related 16 like 1.	Autophagy-related protein 3.	0.979