ATPase family AAA domain containing 5.

BRCA2 DNA repair associated.

ATPase family AAA domain containing 5.

Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily.

ATPase family AAA domain containing 5.

DNA replication helicase/nuclease 2.

ATPase family AAA domain containing 5.

Exonuclease 1.

ATPase family AAA domain containing 5.

F-box DNA helicase 1.

ATPase family AAA domain containing 5.

Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]

ATPase family AAA domain containing 5.

GEN1 Holliday junction 5' flap endonuclease.

ATPase family AAA domain containing 5.

RECA_2 domain-containing protein.

ATPase family AAA domain containing 5.

ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...]

ATPase family AAA domain containing 5.

DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]

ATPase family AAA domain containing 5.

RAD51 paralog B.

ATPase family AAA domain containing 5.

RECA_2 domain-containing protein.

ATPase family AAA domain containing 5.

DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents; Belongs to the RecA family. RAD51 subfamily.

ATPase family AAA domain containing 5.

RAD52 homolog, DNA repair protein.

ATPase family AAA domain containing 5.

RecQ like helicase 4.

ATPase family AAA domain containing 5.

ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.

ATPase family AAA domain containing 5.

WD repeat and HMG-box DNA binding protein 1.

ATPase family AAA domain containing 5.

WRN RecQ like helicase.

ATPase family AAA domain containing 5.

X-ray repair cross complementing 2.

ATPase family AAA domain containing 5.

DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily.