(25 nodes) SUMO is conjugated to E1 (UBA2:SAE1), and PINIT domain network (Cebus capucinus)

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

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Your Input:
	UBE2I	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	TDG	Thymine DNA glycosylase. (410 aa)
	KCTD2	Potassium channel tetramerization domain containing 2. (294 aa)
	SENP7	SUMO specific peptidase 7. (1047 aa)
	PIAS3	Protein inhibitor of activated STAT 3. (628 aa)
	PIAS2	Protein inhibitor of activated STAT 2. (621 aa)
	ENSCCAP00000011053	Ubiquitin-like domain-containing protein. (71 aa)
	ENSCCAP00000012006	UBIQUITIN_CONJUGAT_2 domain-containing protein. (193 aa)
	ENSCCAP00000012432	Rad60-SLD domain-containing protein. (54 aa)
	SUMO3	Ubiquitin-like domain-containing protein. (133 aa)
	ENSCCAP00000015363	Rad60-SLD domain-containing protein. (94 aa)
	PIAS1	Protein inhibitor of activated STAT 1. (653 aa)
	ENSCCAP00000019711	Rad60-SLD domain-containing protein. (68 aa)
	SENP5	SUMO specific peptidase 5. (755 aa)
	ENSCCAP00000019982	Rad60-SLD domain-containing protein. (74 aa)
	LOC108295971	Small ubiquitin-related modifier. (75 aa)
	ENSCCAP00000024201	Ubiquitin-like domain-containing protein. (109 aa)
	SUMO2	Small ubiquitin-related modifier. (80 aa)
	PIAS4	Protein inhibitor of activated STAT 4. (543 aa)
	UBA2	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (524 aa)
	ENSCCAP00000027518	Ubiquitin-like domain-containing protein. (122 aa)
	SAE1	SUMO1 activating enzyme subunit 1. (346 aa)
	ENSCCAP00000030343	Rad60-SLD domain-containing protein. (107 aa)
	SENP1	SUMO specific peptidase 1. (645 aa)
	SENP6	SUMO specific peptidase 6. (1113 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCCAP00000011053	ENSCCAP00000012006	ENSCCAP00000011053	ENSCCAP00000012006	Ubiquitin-like domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein.	0.865
ENSCCAP00000011053	ENSCCAP00000027518	ENSCCAP00000011053	ENSCCAP00000027518	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.413
ENSCCAP00000011053	ENSCCAP00000030343	ENSCCAP00000011053	ENSCCAP00000030343	Ubiquitin-like domain-containing protein.	Rad60-SLD domain-containing protein.	0.411
ENSCCAP00000011053	KCTD2	ENSCCAP00000011053	ENSCCAP00000005274	Ubiquitin-like domain-containing protein.	Potassium channel tetramerization domain containing 2.	0.785
ENSCCAP00000011053	PIAS1	ENSCCAP00000011053	ENSCCAP00000015677	Ubiquitin-like domain-containing protein.	Protein inhibitor of activated STAT 1.	0.842
ENSCCAP00000011053	PIAS2	ENSCCAP00000011053	ENSCCAP00000010206	Ubiquitin-like domain-containing protein.	Protein inhibitor of activated STAT 2.	0.924
ENSCCAP00000011053	PIAS3	ENSCCAP00000011053	ENSCCAP00000005888	Ubiquitin-like domain-containing protein.	Protein inhibitor of activated STAT 3.	0.776
ENSCCAP00000011053	PIAS4	ENSCCAP00000011053	ENSCCAP00000026934	Ubiquitin-like domain-containing protein.	Protein inhibitor of activated STAT 4.	0.806
ENSCCAP00000011053	SAE1	ENSCCAP00000011053	ENSCCAP00000027856	Ubiquitin-like domain-containing protein.	SUMO1 activating enzyme subunit 1.	0.943
ENSCCAP00000011053	SENP1	ENSCCAP00000011053	ENSCCAP00000038117	Ubiquitin-like domain-containing protein.	SUMO specific peptidase 1.	0.911
ENSCCAP00000011053	SENP5	ENSCCAP00000011053	ENSCCAP00000019970	Ubiquitin-like domain-containing protein.	SUMO specific peptidase 5.	0.635
ENSCCAP00000011053	SENP6	ENSCCAP00000011053	ENSCCAP00000038998	Ubiquitin-like domain-containing protein.	SUMO specific peptidase 6.	0.596
ENSCCAP00000011053	SENP7	ENSCCAP00000011053	ENSCCAP00000005768	Ubiquitin-like domain-containing protein.	SUMO specific peptidase 7.	0.598
ENSCCAP00000011053	SUMO2	ENSCCAP00000011053	ENSCCAP00000026274	Ubiquitin-like domain-containing protein.	Small ubiquitin-related modifier.	0.410
ENSCCAP00000011053	SUMO3	ENSCCAP00000011053	ENSCCAP00000013611	Ubiquitin-like domain-containing protein.	Ubiquitin-like domain-containing protein.	0.458
ENSCCAP00000011053	TDG	ENSCCAP00000011053	ENSCCAP00000004676	Ubiquitin-like domain-containing protein.	Thymine DNA glycosylase.	0.907
ENSCCAP00000011053	UBA2	ENSCCAP00000011053	ENSCCAP00000027466	Ubiquitin-like domain-containing protein.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.945
ENSCCAP00000011053	UBE2I	ENSCCAP00000011053	ENSCCAP00000001582	Ubiquitin-like domain-containing protein.	Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family.	0.865
ENSCCAP00000012006	ENSCCAP00000011053	ENSCCAP00000012006	ENSCCAP00000011053	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Ubiquitin-like domain-containing protein.	0.865
ENSCCAP00000012006	ENSCCAP00000012432	ENSCCAP00000012006	ENSCCAP00000012432	UBIQUITIN_CONJUGAT_2 domain-containing protein.	Rad60-SLD domain-containing protein.	0.708