STRINGSTRING
MCM2 MCM2 ORC2 ORC2 GINS3 GINS3 ENSCCAP00000000393 ENSCCAP00000000393 ENSCCAP00000000717 ENSCCAP00000000717 ENSCCAP00000000930 ENSCCAP00000000930 SAP30L SAP30L ENSCCAP00000001091 ENSCCAP00000001091 MACROH2A1 MACROH2A1 TRIM24 TRIM24 ORC4 ORC4 UBE2I UBE2I LRIF1 LRIF1 RPA1 RPA1 LOC108302231 LOC108302231 HIST1H4E HIST1H4E SLX1A SLX1A ZRANB3 ZRANB3 KIFAP3 KIFAP3 NCAPH2 NCAPH2 SAP30 SAP30 STAG2 STAG2 ENSCCAP00000002836 ENSCCAP00000002836 LOC108287010 LOC108287010 LOC108297261 LOC108297261 SYCP2 SYCP2 WDHD1 WDHD1 ENSCCAP00000003596 ENSCCAP00000003596 ENSCCAP00000003603 ENSCCAP00000003603 INCENP INCENP SETD5 SETD5 ENSCCAP00000004129 ENSCCAP00000004129 ENSCCAP00000004268 ENSCCAP00000004268 POLD4 POLD4 ENSCCAP00000004623 ENSCCAP00000004623 SWI5 SWI5 INO80E INO80E ENSCCAP00000004759 ENSCCAP00000004759 MLH1 MLH1 ENSCCAP00000004930 ENSCCAP00000004930 LOC108304268 LOC108304268 ENSCCAP00000005142 ENSCCAP00000005142 ENSCCAP00000005186 ENSCCAP00000005186 SYCP3 SYCP3 POLD3 POLD3 H3C6 H3C6 STAG3 STAG3 ENSCCAP00000005634 ENSCCAP00000005634 LOC108301415 LOC108301415 ENSCCAP00000006343 ENSCCAP00000006343 MUS81 MUS81 ENSCCAP00000006462 ENSCCAP00000006462 ORC6 ORC6 SAP130 SAP130 ENSCCAP00000007246 ENSCCAP00000007246 ARID4B ARID4B DMAP1 DMAP1 SIN3B SIN3B LOC108297589 LOC108297589 FKBP6 FKBP6 DMC1 DMC1 SMARCAD1 SMARCAD1 NOL6 NOL6 RAD51 RAD51 ACTR5 ACTR5 ENSCCAP00000009590 ENSCCAP00000009590 SPO11 SPO11 NFRKB NFRKB ENSCCAP00000009704 ENSCCAP00000009704 DHX9 DHX9 POLE4 POLE4 SMARCAL1 SMARCAL1 SMC4 SMC4 LRWD1 LRWD1 BLM BLM RNF212B RNF212B POLA1 POLA1 ENSCCAP00000010913 ENSCCAP00000010913 ENSCCAP00000011051 ENSCCAP00000011051 ZNHIT1 ZNHIT1 UCHL5 UCHL5 POLD2 POLD2 REC8 REC8 ACTR8 ACTR8 ENSCCAP00000012006 ENSCCAP00000012006 POLA2 POLA2 PBRM1 PBRM1 TET1 TET1 RAD21L1 RAD21L1 HELB HELB ZMIZ2 ZMIZ2 CCNB1IP1 CCNB1IP1 SLX4 SLX4 GINS2 GINS2 MCM4 MCM4 ACTR6 ACTR6 FAM9B FAM9B HMGA2 HMGA2 MCM6 MCM6 LOC108299438 LOC108299438 RPA3 RPA3 SMARCE1 SMARCE1 RUVBL2 RUVBL2 TEX12 TEX12 BRD8 BRD8 NUFIP1 NUFIP1 RPA2 RPA2 ATRX ATRX CDX2 CDX2 NIFK NIFK ENSCCAP00000016251 ENSCCAP00000016251 RCC1 RCC1 LOC108287552 LOC108287552 BRCA1 BRCA1 LOC108314072 LOC108314072 MEI4 MEI4 ENSCCAP00000017980 ENSCCAP00000017980 KMT2E KMT2E OGT OGT SIN3A SIN3A ETAA1 ETAA1 SINHCAF SINHCAF SYCP2L SYCP2L REPIN1 REPIN1 PHF12 PHF12 PLK1 PLK1 SYCE1L SYCE1L INO80C INO80C MMS22L MMS22L SYN1 SYN1 EME2 EME2 SYCE1 SYCE1 SRCAP SRCAP HORMAD1 HORMAD1 CPSF6 CPSF6 BRD4 BRD4 HORMAD2 HORMAD2 INO80D INO80D RGS12 RGS12 MLH3 MLH3 LOC108292630 LOC108292630 TFPT TFPT ENSCCAP00000022407 ENSCCAP00000022407 RSPH1 RSPH1 MCM10 MCM10 ACTL6A ACTL6A CHD1 CHD1 CCDC155 CCDC155 HSPA2 HSPA2 ENSCCAP00000024326 ENSCCAP00000024326 SUN2 SUN2 CHEK1 CHEK1 ENSCCAP00000024677 ENSCCAP00000024677 CCDC36 CCDC36 ORC5 ORC5 SETX SETX NEK2 NEK2 RUVBL1 RUVBL1 ENSCCAP00000025659 ENSCCAP00000025659 EXOSC9 EXOSC9 SMCHD1 SMCHD1 INO80 INO80 ENSCCAP00000026582 ENSCCAP00000026582 RAD9A RAD9A ENSCCAP00000027036 ENSCCAP00000027036 ENSCCAP00000027088 ENSCCAP00000027088 POLD1 POLD1 ENSCCAP00000027377 ENSCCAP00000027377 LOC108298788 LOC108298788 ENSCCAP00000027473 ENSCCAP00000027473 POLE POLE LOC108298207 LOC108298207 SFR1 SFR1 E2F1 E2F1 PINX1 PINX1 LRPPRC LRPPRC ING1 ING1 RRS1 RRS1 LOC108298787 LOC108298787 CDC45 CDC45 ENSCCAP00000028540 ENSCCAP00000028540 ENSCCAP00000028779 ENSCCAP00000028779 ENSCCAP00000029008 ENSCCAP00000029008 TRRAP TRRAP SPIDR SPIDR ORC1 ORC1 GINS4 GINS4 SPEGNB SPEGNB SHOC1 SHOC1 CHRAC1 CHRAC1 TOPBP1 TOPBP1 ORC3 ORC3 CDCA7 CDCA7 KAT5 KAT5 TEX11 TEX11 C14orf39 C14orf39 SMC1A SMC1A BRCA2 BRCA2 SYCE2 SYCE2 LOC108315599 LOC108315599 HUS1 HUS1 SYCP1 SYCP1 AGO3 AGO3 POLE3 POLE3 NCAPG NCAPG INO80B INO80B ING3 ING3 SMC2 SMC2 MCM3 MCM3 MCM5 MCM5 MACROH2A2 MACROH2A2 BRMS1L BRMS1L NCAPH NCAPH ENSCCAP00000033351 ENSCCAP00000033351 CFDP1 CFDP1 TTN TTN GINS1 GINS1 MSH4 MSH4 NCAPG2 NCAPG2 C17orf64 C17orf64 PSMC3IP PSMC3IP SIRT7 SIRT7 SMC3 SMC3 RAD21 RAD21 ENSCCAP00000034455 ENSCCAP00000034455 ENSCCAP00000034488 ENSCCAP00000034488 SYCE3 SYCE3 ENSCCAP00000034537 ENSCCAP00000034537 ENSCCAP00000035444 ENSCCAP00000035444 MCRS1 MCRS1 HDAC2 HDAC2 ING2 ING2 EP400 EP400 SMARCB1 SMARCB1 TONSL TONSL RAD9B RAD9B TIMELESS TIMELESS POLE2 POLE2 ENSCCAP00000037034 ENSCCAP00000037034 ENSCCAP00000037624 ENSCCAP00000037624 P3H4 P3H4 PCNA PCNA MCM7 MCM7 ADD3 ADD3 RNF212 RNF212 SMC1B SMC1B HNRNPU HNRNPU BRMS1 BRMS1 WAPL WAPL HDAC1 HDAC1 LOC108290520 LOC108290520
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MCM2DNA helicase; Belongs to the MCM family. (904 aa)
ORC2Origin recognition complex subunit 2. (577 aa)
GINS3GINS complex subunit 3. (255 aa)
ENSCCAP00000000393Uncharacterized protein. (145 aa)
ENSCCAP00000000717Histone H3; Belongs to the histone H3 family. (136 aa)
ENSCCAP00000000930annotation not available (136 aa)
SAP30LSAP30 like. (182 aa)
ENSCCAP00000001091HMG box domain-containing protein. (382 aa)
MACROH2A1Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (371 aa)
TRIM24Tripartite motif containing 24. (1011 aa)
ORC4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
LRIF1Ligand dependent nuclear receptor interacting factor 1. (759 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (557 aa)
LOC108302231Uncharacterized protein. (142 aa)
HIST1H4EHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
SLX1AStructure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. (275 aa)
ZRANB3Zinc finger RANBP2-type containing 3. (1080 aa)
KIFAP3Kinesin associated protein 3. (799 aa)
NCAPH2Non-SMC condensin II complex subunit H2. (570 aa)
SAP30Sin3A associated protein 30. (220 aa)
STAG2Stromal antigen 2. (1242 aa)
ENSCCAP00000002836annotation not available (103 aa)
LOC108287010Histone H3.1. (136 aa)
LOC108297261Histone H4. (103 aa)
SYCP2Synaptonemal complex protein 2. (1511 aa)
WDHD1WD repeat and HMG-box DNA binding protein 1. (616 aa)
ENSCCAP00000003596annotation not available (103 aa)
ENSCCAP00000003603annotation not available (136 aa)
INCENPInner centromere protein. (924 aa)
SETD5SET domain containing 5. (1461 aa)
ENSCCAP00000004129annotation not available (103 aa)
ENSCCAP00000004268Uncharacterized protein. (73 aa)
POLD4Uncharacterized protein. (107 aa)
ENSCCAP00000004623annotation not available (103 aa)
SWI5SWI5 homologous recombination repair protein. (172 aa)
INO80EINO80 complex subunit E. (244 aa)
ENSCCAP00000004759annotation not available (136 aa)
MLH1MutL homolog 1. (757 aa)
ENSCCAP00000004930annotation not available (103 aa)
LOC108304268Histone H4. (103 aa)
ENSCCAP00000005142annotation not available (103 aa)
ENSCCAP00000005186Uncharacterized protein. (110 aa)
SYCP3Cor1 domain-containing protein. (236 aa)
POLD3DNA polymerase delta 3, accessory subunit. (464 aa)
H3C6H3 clustered histone 6. (136 aa)
STAG3Stromal antigen 3. (1247 aa)
ENSCCAP00000005634Hist_deacetyl domain-containing protein. (305 aa)
LOC108301415Uncharacterized protein. (111 aa)
ENSCCAP00000006343Uncharacterized protein. (117 aa)
MUS81MUS81 structure-specific endonuclease subunit. (552 aa)
ENSCCAP00000006462Uncharacterized protein. (343 aa)
ORC6Origin recognition complex subunit 6. (150 aa)
SAP130SAP130_C domain-containing protein. (1083 aa)
ENSCCAP00000007246Uncharacterized protein. (77 aa)
ARID4BAT-rich interaction domain 4B. (1314 aa)
DMAP1DNA methyltransferase 1 associated protein 1. (467 aa)
SIN3BSIN3 transcription regulator family member B. (1134 aa)
LOC108297589Uncharacterized protein. (430 aa)
FKBP6Peptidylprolyl isomerase. (264 aa)
DMC1Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (311 aa)
SMARCAD1Uncharacterized protein. (1026 aa)
NOL6Nucleolar protein 6. (1146 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
ACTR5Actin related protein 5; Belongs to the actin family. (607 aa)
ENSCCAP00000009590Rad21_Rec8 domain-containing protein. (546 aa)
SPO11SPO11 initiator of meiotic double stranded breaks. (396 aa)
NFRKBNuclear factor related to kappaB binding protein. (1299 aa)
ENSCCAP00000009704Glyco_transf_41 domain-containing protein. (100 aa)
DHX9DExH-box helicase 9. (1136 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (119 aa)
SMARCAL1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (957 aa)
SMC4Structural maintenance of chromosomes protein. (1287 aa)
LRWD1Leucine rich repeats and WD repeat domain containing 1. (647 aa)
BLMBLM RecQ like helicase. (1401 aa)
RNF212BRing finger protein 212B. (275 aa)
POLA1DNA polymerase. (1391 aa)
ENSCCAP00000010913SPRY domain-containing protein. (494 aa)
ENSCCAP00000011051Uncharacterized protein. (203 aa)
ZNHIT1Zinc finger HIT-type containing 1. (154 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase. (396 aa)
POLD2DNA polymerase delta 2, accessory subunit. (498 aa)
REC8REC8 meiotic recombination protein. (548 aa)
ACTR8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa)
ENSCCAP00000012006UBIQUITIN_CONJUGAT_2 domain-containing protein. (193 aa)
POLA2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (609 aa)
PBRM1Polybromo 1. (1725 aa)
TET1Tet methylcytosine dioxygenase 1. (1497 aa)
RAD21L1RAD21 cohesin complex component like 1. (556 aa)
HELBDNA helicase B. (1086 aa)
ZMIZ2Zinc finger MIZ-type containing 2. (920 aa)
CCNB1IP1RING-type domain-containing protein. (277 aa)
SLX4SLX4 structure-specific endonuclease subunit. (1826 aa)
GINS2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa)
MCM4DNA helicase; Belongs to the MCM family. (863 aa)
ACTR6Actin related protein 6; Belongs to the actin family. (396 aa)
FAM9BFamily with sequence similarity 9 member B. (187 aa)
HMGA2Uncharacterized protein. (118 aa)
MCM6DNA helicase; Belongs to the MCM family. (821 aa)
LOC108299438G-patch domain-containing protein. (331 aa)
RPA3Uncharacterized protein. (121 aa)
SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (222 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (468 aa)
TEX12Testis expressed 12. (123 aa)
BRD8Bromo domain-containing protein. (1183 aa)
NUFIP1Nuclear FMR1 interacting protein 1. (444 aa)
RPA2Replication protein A2. (339 aa)
ATRXATRX chromatin remodeler. (2240 aa)
CDX2Caudal type homeobox 2. (311 aa)
NIFKNucleolar protein interacting with the FHA domain of MKI67. (258 aa)
ENSCCAP00000016251Uncharacterized protein. (107 aa)
RCC1Uncharacterized protein. (456 aa)
LOC108287552Cor1 domain-containing protein. (217 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1830 aa)
LOC108314072SAP130_C domain-containing protein. (906 aa)
MEI4Meiotic double-stranded break formation protein 4. (384 aa)
ENSCCAP00000017980Craniofacial development protein 1; May play a role during embryogenesis. (268 aa)
KMT2ELysine methyltransferase 2E. (1858 aa)
OGTTPR_REGION domain-containing protein. (1046 aa)
SIN3ASIN3 transcription regulator family member A. (1273 aa)
ETAA1ETAA1 activator of ATR kinase. (899 aa)
SINHCAFSIN3-HDAC complex associated factor. (221 aa)
SYCP2LSynaptonemal complex protein 2 like. (742 aa)
REPIN1Replication initiator 1. (624 aa)
PHF12PHD finger protein 12. (1004 aa)
PLK1Serine/threonine-protein kinase PLK. (602 aa)
SYCE1LSynaptonemal complex central element protein 1 like. (188 aa)
INO80CYL1_C domain-containing protein. (228 aa)
MMS22LMMS22 like, DNA repair protein. (1241 aa)
SYN1Synapsin I. (706 aa)
EME2Essential meiotic structure-specific endonuclease subunit 2. (372 aa)
SYCE1Synaptonemal complex central element protein 1. (333 aa)
SRCAPUncharacterized protein. (3217 aa)
HORMAD1HORMA domain containing 1. (319 aa)
CPSF6Cleavage and polyadenylation specific factor 6. (589 aa)
BRD4Bromodomain containing 4. (1367 aa)
HORMAD2HORMA domain containing 2. (307 aa)
INO80DINO80 complex subunit D. (1027 aa)
RGS12Regulator of G protein signaling 12. (1437 aa)
MLH3MutL homolog 3. (1456 aa)
LOC108292630EP400_N domain-containing protein. (441 aa)
TFPTTCF3 fusion partner. (244 aa)
ENSCCAP00000022407Uncharacterized protein. (67 aa)
RSPH1Radial spoke head component 1. (310 aa)
MCM10Minichromosome maintenance 10 replication initiation factor. (870 aa)
ACTL6AActin like 6A; Belongs to the actin family. (429 aa)
CHD1Chromodomain helicase DNA binding protein 1. (1674 aa)
CCDC155Coiled-coil domain containing 155. (560 aa)
HSPA2Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (601 aa)
ENSCCAP00000024326Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (131 aa)
SUN2Sad1 and UNC84 domain containing 2. (725 aa)
CHEK1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (476 aa)
ENSCCAP00000024677RING-type domain-containing protein. (259 aa)
CCDC36Coiled-coil domain containing 36. (600 aa)
ORC5Origin recognition complex subunit 5. (435 aa)
SETXSenataxin. (2678 aa)
NEK2NIMA related kinase 2. (445 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
ENSCCAP00000025659HMG box domain-containing protein. (157 aa)
EXOSC9Exosome component 9. (442 aa)
SMCHD1Structural maintenance of chromosomes flexible hinge domain containing 1. (1973 aa)
INO80INO80 complex ATPase subunit. (1556 aa)
ENSCCAP00000026582Cor1 domain-containing protein. (249 aa)
RAD9ACell cycle checkpoint control protein; Belongs to the rad9 family. (391 aa)
ENSCCAP00000027036annotation not available (136 aa)
ENSCCAP00000027088DUF4502 domain-containing protein. (204 aa)
POLD1DNA polymerase. (1105 aa)
ENSCCAP00000027377YL1_C domain-containing protein. (212 aa)
LOC108298788Histone H4. (103 aa)
ENSCCAP00000027473annotation not available (136 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2286 aa)
LOC108298207Histone H4. (103 aa)
SFR1SWI5 dependent homologous recombination repair protein 1. (240 aa)
E2F1E2F transcription factor 1. (438 aa)
PINX1G-patch domain-containing protein. (327 aa)
LRPPRCPPR_long domain-containing protein. (1395 aa)
ING1Inhibitor of growth protein. (387 aa)
RRS1Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (365 aa)
LOC108298787Histone H4. (103 aa)
CDC45Cell division cycle 45. (594 aa)
ENSCCAP00000028540annotation not available (136 aa)
ENSCCAP00000028779UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (186 aa)
ENSCCAP00000029008annotation not available (136 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3789 aa)
SPIDRDUF4503 domain-containing protein. (397 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (858 aa)
GINS4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa)
SPEGNBSPEG neighbor. (238 aa)
SHOC1Shortage in chiasmata 1. (1444 aa)
CHRAC1CBFD_NFYB_HMF domain-containing protein. (131 aa)
TOPBP1DNA topoisomerase II binding protein 1. (1526 aa)
ORC3Origin recognition complex subunit 3. (685 aa)
CDCA7zf-4CXXC_R1 domain-containing protein. (450 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
TEX11Uncharacterized protein. (494 aa)
C14orf39Chromosome 14 open reading frame 39. (587 aa)
SMC1AStructural maintenance of chromosomes protein. (1233 aa)
BRCA2BRCA2 DNA repair associated. (3397 aa)
SYCE2Synaptonemal complex central element protein 2. (178 aa)
LOC108315599SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (368 aa)
HUS1Checkpoint protein; Belongs to the HUS1 family. (280 aa)
SYCP1Synaptonemal complex protein 1. (976 aa)
AGO3Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa)
POLE3DNA polymerase epsilon 3, accessory subunit. (147 aa)
NCAPGNon-SMC condensin I complex subunit G. (1014 aa)
INO80BPAPA-1 domain-containing protein. (372 aa)
ING3Inhibitor of growth protein. (418 aa)
SMC2Structural maintenance of chromosomes protein. (1182 aa)
MCM3DNA helicase; Belongs to the MCM family. (835 aa)
MCM5DNA helicase; Belongs to the MCM family. (734 aa)
MACROH2A2Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
BRMS1LBRMS1 like transcriptional repressor. (323 aa)
NCAPHCondensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (741 aa)
ENSCCAP00000033351annotation not available (131 aa)
CFDP1Craniofacial development protein 1; May play a role during embryogenesis. (298 aa)
TTNUncharacterized protein. (27115 aa)
GINS1GINS complex subunit 1. (196 aa)
MSH4DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (870 aa)
NCAPG2Non-SMC condensin II complex subunit G2. (1144 aa)
C17orf64Chromosome 17 open reading frame 64. (236 aa)
PSMC3IPPSMC3 interacting protein. (217 aa)
SIRT7Sirtuin 7. (421 aa)
SMC3Structural maintenance of chromosomes protein. (1215 aa)
RAD21RAD21 cohesin complex component. (605 aa)
ENSCCAP00000034455G-patch domain-containing protein. (291 aa)
ENSCCAP00000034488Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (91 aa)
SYCE3Synaptonemal complex central element protein 3. (88 aa)
ENSCCAP00000034537Uncharacterized protein. (112 aa)
ENSCCAP00000035444Uncharacterized protein. (296 aa)
MCRS1Microspherule protein 1. (475 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
ING2Inhibitor of growth protein. (279 aa)
EP400E1A binding protein p400. (3118 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa)
TONSLTonsoku like, DNA repair protein. (1375 aa)
RAD9BRAD9 checkpoint clamp component B. (345 aa)
TIMELESSTimeless circadian regulator. (1116 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (534 aa)
ENSCCAP00000037034Histone domain-containing protein. (122 aa)
ENSCCAP00000037624Uncharacterized protein. (450 aa)
P3H4Prolyl 3-hydroxylase family member 4 (non-enzymatic). (437 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (709 aa)
ADD3Adducin 3. (706 aa)
RNF212Ring finger protein 212. (253 aa)
SMC1BStructural maintenance of chromosomes protein. (1235 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (825 aa)
BRMS1BRMS1 transcriptional repressor and anoikis regulator. (284 aa)
WAPLWAPL cohesin release factor. (1191 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
LOC108290520Bromo domain-containing protein. (825 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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