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MCM2 | DNA helicase; Belongs to the MCM family. (904 aa) | ||||
ORC2 | Origin recognition complex subunit 2. (577 aa) | ||||
GINS3 | GINS complex subunit 3. (255 aa) | ||||
ENSCCAP00000000393 | Uncharacterized protein. (145 aa) | ||||
ENSCCAP00000000717 | Histone H3; Belongs to the histone H3 family. (136 aa) | ||||
ENSCCAP00000000930 | annotation not available (136 aa) | ||||
SAP30L | SAP30 like. (182 aa) | ||||
ENSCCAP00000001091 | HMG box domain-containing protein. (382 aa) | ||||
MACROH2A1 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (371 aa) | ||||
TRIM24 | Tripartite motif containing 24. (1011 aa) | ||||
ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa) | ||||
UBE2I | Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (158 aa) | ||||
LRIF1 | Ligand dependent nuclear receptor interacting factor 1. (759 aa) | ||||
RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (557 aa) | ||||
LOC108302231 | Uncharacterized protein. (142 aa) | ||||
HIST1H4E | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) | ||||
SLX1A | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. (275 aa) | ||||
ZRANB3 | Zinc finger RANBP2-type containing 3. (1080 aa) | ||||
KIFAP3 | Kinesin associated protein 3. (799 aa) | ||||
NCAPH2 | Non-SMC condensin II complex subunit H2. (570 aa) | ||||
SAP30 | Sin3A associated protein 30. (220 aa) | ||||
STAG2 | Stromal antigen 2. (1242 aa) | ||||
ENSCCAP00000002836 | annotation not available (103 aa) | ||||
LOC108287010 | Histone H3.1. (136 aa) | ||||
LOC108297261 | Histone H4. (103 aa) | ||||
SYCP2 | Synaptonemal complex protein 2. (1511 aa) | ||||
WDHD1 | WD repeat and HMG-box DNA binding protein 1. (616 aa) | ||||
ENSCCAP00000003596 | annotation not available (103 aa) | ||||
ENSCCAP00000003603 | annotation not available (136 aa) | ||||
INCENP | Inner centromere protein. (924 aa) | ||||
SETD5 | SET domain containing 5. (1461 aa) | ||||
ENSCCAP00000004129 | annotation not available (103 aa) | ||||
ENSCCAP00000004268 | Uncharacterized protein. (73 aa) | ||||
POLD4 | Uncharacterized protein. (107 aa) | ||||
ENSCCAP00000004623 | annotation not available (103 aa) | ||||
SWI5 | SWI5 homologous recombination repair protein. (172 aa) | ||||
INO80E | INO80 complex subunit E. (244 aa) | ||||
ENSCCAP00000004759 | annotation not available (136 aa) | ||||
MLH1 | MutL homolog 1. (757 aa) | ||||
ENSCCAP00000004930 | annotation not available (103 aa) | ||||
LOC108304268 | Histone H4. (103 aa) | ||||
ENSCCAP00000005142 | annotation not available (103 aa) | ||||
ENSCCAP00000005186 | Uncharacterized protein. (110 aa) | ||||
SYCP3 | Cor1 domain-containing protein. (236 aa) | ||||
POLD3 | DNA polymerase delta 3, accessory subunit. (464 aa) | ||||
H3C6 | H3 clustered histone 6. (136 aa) | ||||
STAG3 | Stromal antigen 3. (1247 aa) | ||||
ENSCCAP00000005634 | Hist_deacetyl domain-containing protein. (305 aa) | ||||
LOC108301415 | Uncharacterized protein. (111 aa) | ||||
ENSCCAP00000006343 | Uncharacterized protein. (117 aa) | ||||
MUS81 | MUS81 structure-specific endonuclease subunit. (552 aa) | ||||
ENSCCAP00000006462 | Uncharacterized protein. (343 aa) | ||||
ORC6 | Origin recognition complex subunit 6. (150 aa) | ||||
SAP130 | SAP130_C domain-containing protein. (1083 aa) | ||||
ENSCCAP00000007246 | Uncharacterized protein. (77 aa) | ||||
ARID4B | AT-rich interaction domain 4B. (1314 aa) | ||||
DMAP1 | DNA methyltransferase 1 associated protein 1. (467 aa) | ||||
SIN3B | SIN3 transcription regulator family member B. (1134 aa) | ||||
LOC108297589 | Uncharacterized protein. (430 aa) | ||||
FKBP6 | Peptidylprolyl isomerase. (264 aa) | ||||
DMC1 | Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (311 aa) | ||||
SMARCAD1 | Uncharacterized protein. (1026 aa) | ||||
NOL6 | Nucleolar protein 6. (1146 aa) | ||||
RAD51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa) | ||||
ACTR5 | Actin related protein 5; Belongs to the actin family. (607 aa) | ||||
ENSCCAP00000009590 | Rad21_Rec8 domain-containing protein. (546 aa) | ||||
SPO11 | SPO11 initiator of meiotic double stranded breaks. (396 aa) | ||||
NFRKB | Nuclear factor related to kappaB binding protein. (1299 aa) | ||||
ENSCCAP00000009704 | Glyco_transf_41 domain-containing protein. (100 aa) | ||||
DHX9 | DExH-box helicase 9. (1136 aa) | ||||
POLE4 | DNA polymerase epsilon 4, accessory subunit. (119 aa) | ||||
SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (957 aa) | ||||
SMC4 | Structural maintenance of chromosomes protein. (1287 aa) | ||||
LRWD1 | Leucine rich repeats and WD repeat domain containing 1. (647 aa) | ||||
BLM | BLM RecQ like helicase. (1401 aa) | ||||
RNF212B | Ring finger protein 212B. (275 aa) | ||||
POLA1 | DNA polymerase. (1391 aa) | ||||
ENSCCAP00000010913 | SPRY domain-containing protein. (494 aa) | ||||
ENSCCAP00000011051 | Uncharacterized protein. (203 aa) | ||||
ZNHIT1 | Zinc finger HIT-type containing 1. (154 aa) | ||||
UCHL5 | Ubiquitin carboxyl-terminal hydrolase. (396 aa) | ||||
POLD2 | DNA polymerase delta 2, accessory subunit. (498 aa) | ||||
REC8 | REC8 meiotic recombination protein. (548 aa) | ||||
ACTR8 | Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa) | ||||
ENSCCAP00000012006 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (193 aa) | ||||
POLA2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (609 aa) | ||||
PBRM1 | Polybromo 1. (1725 aa) | ||||
TET1 | Tet methylcytosine dioxygenase 1. (1497 aa) | ||||
RAD21L1 | RAD21 cohesin complex component like 1. (556 aa) | ||||
HELB | DNA helicase B. (1086 aa) | ||||
ZMIZ2 | Zinc finger MIZ-type containing 2. (920 aa) | ||||
CCNB1IP1 | RING-type domain-containing protein. (277 aa) | ||||
SLX4 | SLX4 structure-specific endonuclease subunit. (1826 aa) | ||||
GINS2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa) | ||||
MCM4 | DNA helicase; Belongs to the MCM family. (863 aa) | ||||
ACTR6 | Actin related protein 6; Belongs to the actin family. (396 aa) | ||||
FAM9B | Family with sequence similarity 9 member B. (187 aa) | ||||
HMGA2 | Uncharacterized protein. (118 aa) | ||||
MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) | ||||
LOC108299438 | G-patch domain-containing protein. (331 aa) | ||||
RPA3 | Uncharacterized protein. (121 aa) | ||||
SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (222 aa) | ||||
RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (468 aa) | ||||
TEX12 | Testis expressed 12. (123 aa) | ||||
BRD8 | Bromo domain-containing protein. (1183 aa) | ||||
NUFIP1 | Nuclear FMR1 interacting protein 1. (444 aa) | ||||
RPA2 | Replication protein A2. (339 aa) | ||||
ATRX | ATRX chromatin remodeler. (2240 aa) | ||||
CDX2 | Caudal type homeobox 2. (311 aa) | ||||
NIFK | Nucleolar protein interacting with the FHA domain of MKI67. (258 aa) | ||||
ENSCCAP00000016251 | Uncharacterized protein. (107 aa) | ||||
RCC1 | Uncharacterized protein. (456 aa) | ||||
LOC108287552 | Cor1 domain-containing protein. (217 aa) | ||||
BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1830 aa) | ||||
LOC108314072 | SAP130_C domain-containing protein. (906 aa) | ||||
MEI4 | Meiotic double-stranded break formation protein 4. (384 aa) | ||||
ENSCCAP00000017980 | Craniofacial development protein 1; May play a role during embryogenesis. (268 aa) | ||||
KMT2E | Lysine methyltransferase 2E. (1858 aa) | ||||
OGT | TPR_REGION domain-containing protein. (1046 aa) | ||||
SIN3A | SIN3 transcription regulator family member A. (1273 aa) | ||||
ETAA1 | ETAA1 activator of ATR kinase. (899 aa) | ||||
SINHCAF | SIN3-HDAC complex associated factor. (221 aa) | ||||
SYCP2L | Synaptonemal complex protein 2 like. (742 aa) | ||||
REPIN1 | Replication initiator 1. (624 aa) | ||||
PHF12 | PHD finger protein 12. (1004 aa) | ||||
PLK1 | Serine/threonine-protein kinase PLK. (602 aa) | ||||
SYCE1L | Synaptonemal complex central element protein 1 like. (188 aa) | ||||
INO80C | YL1_C domain-containing protein. (228 aa) | ||||
MMS22L | MMS22 like, DNA repair protein. (1241 aa) | ||||
SYN1 | Synapsin I. (706 aa) | ||||
EME2 | Essential meiotic structure-specific endonuclease subunit 2. (372 aa) | ||||
SYCE1 | Synaptonemal complex central element protein 1. (333 aa) | ||||
SRCAP | Uncharacterized protein. (3217 aa) | ||||
HORMAD1 | HORMA domain containing 1. (319 aa) | ||||
CPSF6 | Cleavage and polyadenylation specific factor 6. (589 aa) | ||||
BRD4 | Bromodomain containing 4. (1367 aa) | ||||
HORMAD2 | HORMA domain containing 2. (307 aa) | ||||
INO80D | INO80 complex subunit D. (1027 aa) | ||||
RGS12 | Regulator of G protein signaling 12. (1437 aa) | ||||
MLH3 | MutL homolog 3. (1456 aa) | ||||
LOC108292630 | EP400_N domain-containing protein. (441 aa) | ||||
TFPT | TCF3 fusion partner. (244 aa) | ||||
ENSCCAP00000022407 | Uncharacterized protein. (67 aa) | ||||
RSPH1 | Radial spoke head component 1. (310 aa) | ||||
MCM10 | Minichromosome maintenance 10 replication initiation factor. (870 aa) | ||||
ACTL6A | Actin like 6A; Belongs to the actin family. (429 aa) | ||||
CHD1 | Chromodomain helicase DNA binding protein 1. (1674 aa) | ||||
CCDC155 | Coiled-coil domain containing 155. (560 aa) | ||||
HSPA2 | Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (601 aa) | ||||
ENSCCAP00000024326 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (131 aa) | ||||
SUN2 | Sad1 and UNC84 domain containing 2. (725 aa) | ||||
CHEK1 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. (476 aa) | ||||
ENSCCAP00000024677 | RING-type domain-containing protein. (259 aa) | ||||
CCDC36 | Coiled-coil domain containing 36. (600 aa) | ||||
ORC5 | Origin recognition complex subunit 5. (435 aa) | ||||
SETX | Senataxin. (2678 aa) | ||||
NEK2 | NIMA related kinase 2. (445 aa) | ||||
RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) | ||||
ENSCCAP00000025659 | HMG box domain-containing protein. (157 aa) | ||||
EXOSC9 | Exosome component 9. (442 aa) | ||||
SMCHD1 | Structural maintenance of chromosomes flexible hinge domain containing 1. (1973 aa) | ||||
INO80 | INO80 complex ATPase subunit. (1556 aa) | ||||
ENSCCAP00000026582 | Cor1 domain-containing protein. (249 aa) | ||||
RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (391 aa) | ||||
ENSCCAP00000027036 | annotation not available (136 aa) | ||||
ENSCCAP00000027088 | DUF4502 domain-containing protein. (204 aa) | ||||
POLD1 | DNA polymerase. (1105 aa) | ||||
ENSCCAP00000027377 | YL1_C domain-containing protein. (212 aa) | ||||
LOC108298788 | Histone H4. (103 aa) | ||||
ENSCCAP00000027473 | annotation not available (136 aa) | ||||
POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2286 aa) | ||||
LOC108298207 | Histone H4. (103 aa) | ||||
SFR1 | SWI5 dependent homologous recombination repair protein 1. (240 aa) | ||||
E2F1 | E2F transcription factor 1. (438 aa) | ||||
PINX1 | G-patch domain-containing protein. (327 aa) | ||||
LRPPRC | PPR_long domain-containing protein. (1395 aa) | ||||
ING1 | Inhibitor of growth protein. (387 aa) | ||||
RRS1 | Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (365 aa) | ||||
LOC108298787 | Histone H4. (103 aa) | ||||
CDC45 | Cell division cycle 45. (594 aa) | ||||
ENSCCAP00000028540 | annotation not available (136 aa) | ||||
ENSCCAP00000028779 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (186 aa) | ||||
ENSCCAP00000029008 | annotation not available (136 aa) | ||||
TRRAP | Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3789 aa) | ||||
SPIDR | DUF4503 domain-containing protein. (397 aa) | ||||
ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (858 aa) | ||||
GINS4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa) | ||||
SPEGNB | SPEG neighbor. (238 aa) | ||||
SHOC1 | Shortage in chiasmata 1. (1444 aa) | ||||
CHRAC1 | CBFD_NFYB_HMF domain-containing protein. (131 aa) | ||||
TOPBP1 | DNA topoisomerase II binding protein 1. (1526 aa) | ||||
ORC3 | Origin recognition complex subunit 3. (685 aa) | ||||
CDCA7 | zf-4CXXC_R1 domain-containing protein. (450 aa) | ||||
KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa) | ||||
TEX11 | Uncharacterized protein. (494 aa) | ||||
C14orf39 | Chromosome 14 open reading frame 39. (587 aa) | ||||
SMC1A | Structural maintenance of chromosomes protein. (1233 aa) | ||||
BRCA2 | BRCA2 DNA repair associated. (3397 aa) | ||||
SYCE2 | Synaptonemal complex central element protein 2. (178 aa) | ||||
LOC108315599 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (368 aa) | ||||
HUS1 | Checkpoint protein; Belongs to the HUS1 family. (280 aa) | ||||
SYCP1 | Synaptonemal complex protein 1. (976 aa) | ||||
AGO3 | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa) | ||||
POLE3 | DNA polymerase epsilon 3, accessory subunit. (147 aa) | ||||
NCAPG | Non-SMC condensin I complex subunit G. (1014 aa) | ||||
INO80B | PAPA-1 domain-containing protein. (372 aa) | ||||
ING3 | Inhibitor of growth protein. (418 aa) | ||||
SMC2 | Structural maintenance of chromosomes protein. (1182 aa) | ||||
MCM3 | DNA helicase; Belongs to the MCM family. (835 aa) | ||||
MCM5 | DNA helicase; Belongs to the MCM family. (734 aa) | ||||
MACROH2A2 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa) | ||||
BRMS1L | BRMS1 like transcriptional repressor. (323 aa) | ||||
NCAPH | Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (741 aa) | ||||
ENSCCAP00000033351 | annotation not available (131 aa) | ||||
CFDP1 | Craniofacial development protein 1; May play a role during embryogenesis. (298 aa) | ||||
TTN | Uncharacterized protein. (27115 aa) | ||||
GINS1 | GINS complex subunit 1. (196 aa) | ||||
MSH4 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (870 aa) | ||||
NCAPG2 | Non-SMC condensin II complex subunit G2. (1144 aa) | ||||
C17orf64 | Chromosome 17 open reading frame 64. (236 aa) | ||||
PSMC3IP | PSMC3 interacting protein. (217 aa) | ||||
SIRT7 | Sirtuin 7. (421 aa) | ||||
SMC3 | Structural maintenance of chromosomes protein. (1215 aa) | ||||
RAD21 | RAD21 cohesin complex component. (605 aa) | ||||
ENSCCAP00000034455 | G-patch domain-containing protein. (291 aa) | ||||
ENSCCAP00000034488 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (91 aa) | ||||
SYCE3 | Synaptonemal complex central element protein 3. (88 aa) | ||||
ENSCCAP00000034537 | Uncharacterized protein. (112 aa) | ||||
ENSCCAP00000035444 | Uncharacterized protein. (296 aa) | ||||
MCRS1 | Microspherule protein 1. (475 aa) | ||||
HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) | ||||
ING2 | Inhibitor of growth protein. (279 aa) | ||||
EP400 | E1A binding protein p400. (3118 aa) | ||||
SMARCB1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa) | ||||
TONSL | Tonsoku like, DNA repair protein. (1375 aa) | ||||
RAD9B | RAD9 checkpoint clamp component B. (345 aa) | ||||
TIMELESS | Timeless circadian regulator. (1116 aa) | ||||
POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (534 aa) | ||||
ENSCCAP00000037034 | Histone domain-containing protein. (122 aa) | ||||
ENSCCAP00000037624 | Uncharacterized protein. (450 aa) | ||||
P3H4 | Prolyl 3-hydroxylase family member 4 (non-enzymatic). (437 aa) | ||||
PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) | ||||
MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (709 aa) | ||||
ADD3 | Adducin 3. (706 aa) | ||||
RNF212 | Ring finger protein 212. (253 aa) | ||||
SMC1B | Structural maintenance of chromosomes protein. (1235 aa) | ||||
HNRNPU | Heterogeneous nuclear ribonucleoprotein U. (825 aa) | ||||
BRMS1 | BRMS1 transcriptional repressor and anoikis regulator. (284 aa) | ||||
WAPL | WAPL cohesin release factor. (1191 aa) | ||||
HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa) | ||||
LOC108290520 | Bromo domain-containing protein. (825 aa) |