15 items (Cebus capucinus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

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protein homology

Your Input:
	BRCA2	BRCA2 DNA repair associated. (3397 aa)
	SMC3	Structural maintenance of chromosomes protein. (1215 aa)
	STAG3	Stromal antigen 3. (1247 aa)
	SMC1B	Structural maintenance of chromosomes protein. (1235 aa)
	RAD51	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
	BLM	BLM RecQ like helicase. (1401 aa)
	SYCP3	Cor1 domain-containing protein. (236 aa)
	INCENP	Inner centromere protein. (924 aa)
	SYCP2	Synaptonemal complex protein 2. (1511 aa)
	REC8	REC8 meiotic recombination protein. (548 aa)
	LOC108287552	Cor1 domain-containing protein. (217 aa)
	BRCA1	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1830 aa)
	MEI4	Meiotic double-stranded break formation protein 4. (384 aa)
	SYCP2L	Synaptonemal complex protein 2 like. (742 aa)
	CCDC155	Coiled-coil domain containing 155. (560 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BLM	BRCA1	ENSCCAP00000010639	ENSCCAP00000017232	BLM RecQ like helicase.	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	0.887
BLM	BRCA2	ENSCCAP00000010639	ENSCCAP00000031676	BLM RecQ like helicase.	BRCA2 DNA repair associated.	0.837
BLM	RAD51	ENSCCAP00000010639	ENSCCAP00000009344	BLM RecQ like helicase.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.979
BLM	SMC3	ENSCCAP00000010639	ENSCCAP00000034356	BLM RecQ like helicase.	Structural maintenance of chromosomes protein.	0.430
BRCA1	BLM	ENSCCAP00000017232	ENSCCAP00000010639	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	BLM RecQ like helicase.	0.887
BRCA1	BRCA2	ENSCCAP00000017232	ENSCCAP00000031676	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	BRCA2 DNA repair associated.	0.998
BRCA1	RAD51	ENSCCAP00000017232	ENSCCAP00000009344	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.989
BRCA1	REC8	ENSCCAP00000017232	ENSCCAP00000011813	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	REC8 meiotic recombination protein.	0.674
BRCA1	SMC1B	ENSCCAP00000017232	ENSCCAP00000039735	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	Structural maintenance of chromosomes protein.	0.423
BRCA1	SMC3	ENSCCAP00000017232	ENSCCAP00000034356	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	Structural maintenance of chromosomes protein.	0.415
BRCA2	BLM	ENSCCAP00000031676	ENSCCAP00000010639	BRCA2 DNA repair associated.	BLM RecQ like helicase.	0.837
BRCA2	BRCA1	ENSCCAP00000031676	ENSCCAP00000017232	BRCA2 DNA repair associated.	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	0.998
BRCA2	LOC108287552	ENSCCAP00000031676	ENSCCAP00000017208	BRCA2 DNA repair associated.	Cor1 domain-containing protein.	0.877
BRCA2	RAD51	ENSCCAP00000031676	ENSCCAP00000009344	BRCA2 DNA repair associated.	DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...]	0.998
BRCA2	SMC3	ENSCCAP00000031676	ENSCCAP00000034356	BRCA2 DNA repair associated.	Structural maintenance of chromosomes protein.	0.550
BRCA2	SYCP3	ENSCCAP00000031676	ENSCCAP00000005188	BRCA2 DNA repair associated.	Cor1 domain-containing protein.	0.877
CCDC155	STAG3	ENSCCAP00000023526	ENSCCAP00000005594	Coiled-coil domain containing 155.	Stromal antigen 3.	0.405
INCENP	REC8	ENSCCAP00000003672	ENSCCAP00000011813	Inner centromere protein.	REC8 meiotic recombination protein.	0.408
LOC108287552	BRCA2	ENSCCAP00000017208	ENSCCAP00000031676	Cor1 domain-containing protein.	BRCA2 DNA repair associated.	0.877
LOC108287552	REC8	ENSCCAP00000017208	ENSCCAP00000011813	Cor1 domain-containing protein.	REC8 meiotic recombination protein.	0.565