STRINGSTRING
SP1 SP1 CREBBP CREBBP CTNNB1 CTNNB1 ENSCCAP00000015709 ENSCCAP00000015709 SIX3 SIX3 CREB3 CREB3 ETS1 ETS1 CCNT2 CCNT2 LOC108297026 LOC108297026 NR5A1 NR5A1 ENSCCAP00000013648 ENSCCAP00000013648 HMGA1 HMGA1 ENSCCAP00000012593 ENSCCAP00000012593 GATA2 GATA2 ENSCCAP00000012006 ENSCCAP00000012006 LEF1 LEF1 ZBTB49 ZBTB49 HDAC3 HDAC3 ELOC ELOC SMARCD3 SMARCD3 LCOR LCOR AR AR RELA RELA GATA6 GATA6 CIT CIT RARA RARA EHMT1 EHMT1 NR5A2 NR5A2 BAIAP2 BAIAP2 NR1H4 NR1H4 ZNF618 ZNF618 RUNX3 RUNX3 LOC108298753 LOC108298753 SMAD3 SMAD3 ENSCCAP00000005634 ENSCCAP00000005634 ENSCCAP00000005370 ENSCCAP00000005370 ENSCCAP00000005168 ENSCCAP00000005168 ENSCCAP00000004889 ENSCCAP00000004889 NEK6 NEK6 PHF1 PHF1 SREBF1 SREBF1 ENSCCAP00000003201 ENSCCAP00000003201 PER3 PER3 EZH2 EZH2 THRB THRB PER2 PER2 LOC108305078 LOC108305078 CHD4 CHD4 LOC108282717 LOC108282717 EED EED UBE2I UBE2I ELOB ELOB LOC108293510 LOC108293510 GATA3 GATA3 ENSCCAP00000000829 ENSCCAP00000000829 MED1 MED1 CTCF CTCF CTBP2 CTBP2 ZBTB16 ZBTB16 ENSCCAP00000000187 ENSCCAP00000000187 THAP7 THAP7 LMO2 LMO2 BCL6 BCL6 RORA RORA WIZ WIZ NFATC1 NFATC1 PHF12 PHF12 PAX6 PAX6 CBX3 CBX3 HAND2 HAND2 STK36 STK36 TP73 TP73 HIF1A HIF1A ZNF644 ZNF644 PPARA PPARA TEAD2 TEAD2 ZBTB8A ZBTB8A TERT TERT ZBTB7A ZBTB7A ESR1 ESR1 FAM89B FAM89B ENSCCAP00000027427 ENSCCAP00000027427 LOC108293547 LOC108293547 MED25 MED25 NR1D1 NR1D1 STAT1 STAT1 HDGF HDGF RXRA RXRA SMARCA4 SMARCA4 ENSCCAP00000028779 ENSCCAP00000028779 RUNX1 RUNX1 VGLL4 VGLL4 GATA1 GATA1 SMAD4 SMAD4 NFKB1 NFKB1 NFE2L2 NFE2L2 CNOT2 CNOT2 ATF7 ATF7 EPAS1 EPAS1 CDK9 CDK9 USP11 USP11 PPARD PPARD HNF1A HNF1A ZBTB17 ZBTB17 EHMT2 EHMT2 EP300 EP300 CHD6 CHD6 HAND1 HAND1 CTBP1 CTBP1 PER1 PER1 TRERF1 TRERF1 HDAC6 HDAC6 TFAM TFAM SUZ12 SUZ12 MTF2 MTF2 HDAC1 HDAC1 FOS FOS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SP1Sp1 transcription factor. (786 aa)
CREBBPCREB binding protein. (2448 aa)
CTNNB1Catenin beta 1. (781 aa)
ENSCCAP00000015709Uncharacterized protein. (643 aa)
SIX3SIX homeobox 3. (331 aa)
CREB3cAMP responsive element binding protein 3. (374 aa)
ETS1ETS proto-oncogene 1, transcription factor. (485 aa)
CCNT2Cyclin T2; Belongs to the cyclin family. (730 aa)
LOC108297026Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (331 aa)
NR5A1Nuclear receptor subfamily 5 group A member 1. (461 aa)
ENSCCAP00000013648Uncharacterized protein. (138 aa)
HMGA1High mobility group AT-hook 1. (107 aa)
ENSCCAP00000012593Uncharacterized protein. (154 aa)
GATA2GATA binding protein 2. (480 aa)
ENSCCAP00000012006UBIQUITIN_CONJUGAT_2 domain-containing protein. (193 aa)
LEF1Lymphoid enhancer binding factor 1. (399 aa)
ZBTB49Uncharacterized protein. (248 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
ELOCElongin C. (112 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (475 aa)
LCORLigand dependent nuclear receptor corepressor. (1693 aa)
ARAndrogen receptor. (887 aa)
RELARELA proto-oncogene, NF-kB subunit. (551 aa)
GATA6GATA binding protein 6. (592 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2069 aa)
RARARetinoic acid receptor alpha. (464 aa)
EHMT1Euchromatic histone lysine methyltransferase 1. (1284 aa)
NR5A2Nuclear receptor subfamily 5 group A member 2. (541 aa)
BAIAP2BAI1 associated protein 2. (554 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (486 aa)
ZNF618Zinc finger protein 618. (954 aa)
RUNX3Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (430 aa)
LOC108298753Uncharacterized protein. (242 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
ENSCCAP00000005634Hist_deacetyl domain-containing protein. (305 aa)
ENSCCAP00000005370Uncharacterized protein. (97 aa)
ENSCCAP00000005168Uncharacterized protein. (98 aa)
ENSCCAP00000004889Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
NEK6NIMA related kinase 6; Belongs to the protein kinase superfamily. (347 aa)
PHF1PHD finger protein 1. (566 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1185 aa)
ENSCCAP00000003201Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
PER3Period circadian regulator 3. (1147 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa)
THRBThyroid hormone receptor beta. (476 aa)
PER2Period circadian regulator 2. (1249 aa)
LOC108305078Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (407 aa)
CHD4Uncharacterized protein. (1912 aa)
LOC108282717UBP-type domain-containing protein. (1057 aa)
EEDEmbryonic ectoderm development. (466 aa)
UBE2IUbiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
ELOBElongin B. (157 aa)
LOC108293510Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
GATA3GATA binding protein 3. (444 aa)
ENSCCAP00000000829Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1517 aa)
CTCFCCCTC-binding factor. (676 aa)
CTBP2C-terminal binding protein 2. (927 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
ENSCCAP00000000187Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
THAP7THAP domain containing 7. (309 aa)
LMO2LIM domain only 2. (220 aa)
BCL6BCL6 transcription repressor. (706 aa)
RORARAR related orphan receptor A. (489 aa)
WIZWIZ zinc finger. (968 aa)
NFATC1Nuclear factor of activated T cells 1. (1052 aa)
PHF12PHD finger protein 12. (1004 aa)
PAX6Paired box 6. (447 aa)
CBX3Uncharacterized protein. (183 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
STK36Serine/threonine kinase 36. (1309 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (635 aa)
HIF1AUncharacterized protein. (848 aa)
ZNF644Zinc finger protein 644. (1326 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
TEAD2TEA domain transcription factor 2. (451 aa)
ZBTB8AZinc finger and BTB domain containing 8A. (441 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1121 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (584 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
FAM89BFamily with sequence similarity 89 member B. (153 aa)
ENSCCAP00000027427Uncharacterized protein. (202 aa)
LOC108293547Uncharacterized protein. (773 aa)
MED25Uncharacterized protein. (796 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (615 aa)
STAT1Signal transducer and activator of transcription. (768 aa)
HDGFHeparin binding growth factor. (256 aa)
RXRARetinoid X receptor alpha. (455 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1642 aa)
ENSCCAP00000028779UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (186 aa)
RUNX1Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
VGLL4Vestigial like family member 4. (296 aa)
GATA1GATA binding protein 1. (413 aa)
SMAD4Mothers against decapentaplegic homolog. (469 aa)
NFKB1Nuclear factor kappa B subunit 1. (968 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (606 aa)
CNOT2CCR4-NOT transcription complex subunit 2. (546 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (483 aa)
EPAS1Endothelial PAS domain protein 1. (867 aa)
CDK9Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (372 aa)
USP11Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (972 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
HNF1AHNF1 homeobox A. (661 aa)
ZBTB17Zinc finger and BTB domain containing 17. (779 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1268 aa)
EP300E1A binding protein p300. (2420 aa)
CHD6Chromodomain helicase DNA binding protein 6. (2716 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
CTBP1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (458 aa)
PER1Period circadian regulator 1. (1292 aa)
TRERF1Transcriptional regulating factor 1. (1216 aa)
HDAC6Histone deacetylase 6. (1213 aa)
TFAMTranscription factor A, mitochondrial. (249 aa)
SUZ12SUZ12 polycomb repressive complex 2 subunit. (739 aa)
MTF2Metal response element binding transcription factor 2. (596 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.