53 items (Cebus capucinus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RUNX1	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
	ENSCCAP00000000187	Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
	ZBTB16	Zinc finger and BTB domain containing 16. (673 aa)
	CTBP2	C-terminal binding protein 2. (927 aa)
	ENSCCAP00000000829	Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
	LOC108293510	Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
	ELOB	Elongin B. (157 aa)
	EED	Embryonic ectoderm development. (466 aa)
	LOC108282717	UBP-type domain-containing protein. (1057 aa)
	LOC108305078	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (407 aa)
	PER2	Period circadian regulator 2. (1249 aa)
	EZH2	Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa)
	PER3	Period circadian regulator 3. (1147 aa)
	ENSCCAP00000003201	Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
	PHF1	PHD finger protein 1. (566 aa)
	NEK6	NIMA related kinase 6; Belongs to the protein kinase superfamily. (347 aa)
	ENSCCAP00000004889	Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
	ENSCCAP00000005168	Uncharacterized protein. (98 aa)
	ENSCCAP00000005634	Hist_deacetyl domain-containing protein. (305 aa)
	LOC108298753	Uncharacterized protein. (242 aa)
	RUNX3	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (430 aa)
	EHMT1	Euchromatic histone lysine methyltransferase 1. (1284 aa)
	LCOR	Ligand dependent nuclear receptor corepressor. (1693 aa)
	ELOC	Elongin C. (112 aa)
	HDAC3	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
	LEF1	Lymphoid enhancer binding factor 1. (399 aa)
	ENSCCAP00000013648	Uncharacterized protein. (138 aa)
	ETS1	ETS proto-oncogene 1, transcription factor. (485 aa)
	SIX3	SIX homeobox 3. (331 aa)
	THAP7	THAP domain containing 7. (309 aa)
	BCL6	BCL6 transcription repressor. (706 aa)
	RORA	RAR related orphan receptor A. (489 aa)
	WIZ	WIZ zinc finger. (968 aa)
	PHF12	PHD finger protein 12. (1004 aa)
	STK36	Serine/threonine kinase 36. (1309 aa)
	TP73	Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (635 aa)
	ZNF644	Zinc finger protein 644. (1326 aa)
	ZBTB7A	Zinc finger and BTB domain containing 7A. (584 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
	FAM89B	Family with sequence similarity 89 member B. (153 aa)
	ENSCCAP00000027427	Uncharacterized protein. (202 aa)
	NR1D1	Nuclear receptor subfamily 1 group D member 1. (615 aa)
	STAT1	Signal transducer and activator of transcription. (768 aa)
	HDGF	Heparin binding growth factor. (256 aa)
	CNOT2	CCR4-NOT transcription complex subunit 2. (546 aa)
	USP11	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (972 aa)
	EHMT2	Euchromatic histone lysine methyltransferase 2. (1268 aa)
	CTBP1	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (458 aa)
	PER1	Period circadian regulator 1. (1292 aa)
	HDAC6	Histone deacetylase 6. (1213 aa)
	SUZ12	SUZ12 polycomb repressive complex 2 subunit. (739 aa)
	MTF2	Metal response element binding transcription factor 2. (596 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL6	ENSCCAP00000005634	ENSCCAP00000017061	ENSCCAP00000005634	BCL6 transcription repressor.	Hist_deacetyl domain-containing protein.	0.666
BCL6	EZH2	ENSCCAP00000017061	ENSCCAP00000003110	BCL6 transcription repressor.	Enhancer of zeste 2 polycomb repressive complex 2 subunit.	0.430
BCL6	HDAC1	ENSCCAP00000017061	ENSCCAP00000040358	BCL6 transcription repressor.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.666
BCL6	STAT1	ENSCCAP00000017061	ENSCCAP00000027855	BCL6 transcription repressor.	Signal transducer and activator of transcription.	0.655
CNOT2	ZNF644	ENSCCAP00000032296	ENSCCAP00000021829	CCR4-NOT transcription complex subunit 2.	Zinc finger protein 644.	0.650
CTBP1	CTBP2	ENSCCAP00000038463	ENSCCAP00000000351	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	C-terminal binding protein 2.	0.985
CTBP1	EHMT1	ENSCCAP00000038463	ENSCCAP00000007878	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Euchromatic histone lysine methyltransferase 1.	0.444
CTBP1	EHMT2	ENSCCAP00000038463	ENSCCAP00000036143	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Euchromatic histone lysine methyltransferase 2.	0.510
CTBP1	ENSCCAP00000005634	ENSCCAP00000038463	ENSCCAP00000005634	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Hist_deacetyl domain-containing protein.	0.958
CTBP1	HDAC1	ENSCCAP00000038463	ENSCCAP00000040358	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.958
CTBP1	HDAC3	ENSCCAP00000038463	ENSCCAP00000011283	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.443
CTBP1	LCOR	ENSCCAP00000038463	ENSCCAP00000010340	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Ligand dependent nuclear receptor corepressor.	0.869
CTBP1	LEF1	ENSCCAP00000038463	ENSCCAP00000011489	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Lymphoid enhancer binding factor 1.	0.813
CTBP1	LOC108298753	ENSCCAP00000038463	ENSCCAP00000006205	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Uncharacterized protein.	0.443
CTBP1	LOC108305078	ENSCCAP00000038463	ENSCCAP00000002574	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.985
CTBP1	RUNX1	ENSCCAP00000038463	ENSCCAP00000028867	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.943
CTBP1	RUNX3	ENSCCAP00000038463	ENSCCAP00000006499	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.494
CTBP1	WIZ	ENSCCAP00000038463	ENSCCAP00000017829	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	WIZ zinc finger.	0.709
CTBP2	CTBP1	ENSCCAP00000000351	ENSCCAP00000038463	C-terminal binding protein 2.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.985
CTBP2	ENSCCAP00000005634	ENSCCAP00000000351	ENSCCAP00000005634	C-terminal binding protein 2.	Hist_deacetyl domain-containing protein.	0.824