19 items (Cebus capucinus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	INTS1	Integrator complex subunit 1. (2195 aa)
	RAD51B	RAD51 paralog B. (426 aa)
	SBDS	SBDS ribosome maturation factor. (250 aa)
	TAF8	TATA-box binding protein associated factor 8. (312 aa)
	ENSCCAP00000000953	Uncharacterized protein. (966 aa)
	CTR9	CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa)
	PELO	Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (385 aa)
	ACVR1C	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (450 aa)
	NCAPG2	Non-SMC condensin II complex subunit G2. (1144 aa)
	GINS1	GINS complex subunit 1. (196 aa)
	COPS2	COP9 signalosome subunit 2. (450 aa)
	BRCA2	BRCA2 DNA repair associated. (3397 aa)
	NBN	Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (753 aa)
	GINS4	DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa)
	PALB2	Partner and localizer of BRCA2. (1179 aa)
	CHEK1	Checkpoint kinase 1; Belongs to the protein kinase superfamily. (476 aa)
	SALL4	Uncharacterized protein. (1012 aa)
	ZPR1	ZPR1 zinc finger. (459 aa)
	RTF1	RTF1 homolog, Paf1/RNA polymerase II complex component. (643 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRCA2	CHEK1	ENSCCAP00000031676	ENSCCAP00000024527	BRCA2 DNA repair associated.	Checkpoint kinase 1; Belongs to the protein kinase superfamily.	0.669
BRCA2	NBN	ENSCCAP00000031676	ENSCCAP00000031403	BRCA2 DNA repair associated.	Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.	0.801
BRCA2	PALB2	ENSCCAP00000031676	ENSCCAP00000026053	BRCA2 DNA repair associated.	Partner and localizer of BRCA2.	0.999
BRCA2	RAD51B	ENSCCAP00000031676	ENSCCAP00000009631	BRCA2 DNA repair associated.	RAD51 paralog B.	0.965
CHEK1	BRCA2	ENSCCAP00000024527	ENSCCAP00000031676	Checkpoint kinase 1; Belongs to the protein kinase superfamily.	BRCA2 DNA repair associated.	0.669
CHEK1	GINS4	ENSCCAP00000024527	ENSCCAP00000029371	Checkpoint kinase 1; Belongs to the protein kinase superfamily.	DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.	0.487
CHEK1	NBN	ENSCCAP00000024527	ENSCCAP00000031403	Checkpoint kinase 1; Belongs to the protein kinase superfamily.	Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.	0.713
CHEK1	RAD51B	ENSCCAP00000024527	ENSCCAP00000009631	Checkpoint kinase 1; Belongs to the protein kinase superfamily.	RAD51 paralog B.	0.792
CTR9	INTS1	ENSCCAP00000040474	ENSCCAP00000015419	CTR9 homolog, Paf1/RNA polymerase II complex component.	Integrator complex subunit 1.	0.482
CTR9	RTF1	ENSCCAP00000040474	ENSCCAP00000019179	CTR9 homolog, Paf1/RNA polymerase II complex component.	RTF1 homolog, Paf1/RNA polymerase II complex component.	0.994
GINS1	GINS4	ENSCCAP00000033536	ENSCCAP00000029371	GINS complex subunit 1.	DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.	0.998
GINS1	NCAPG2	ENSCCAP00000033536	ENSCCAP00000033583	GINS complex subunit 1.	Non-SMC condensin II complex subunit G2.	0.491
GINS4	CHEK1	ENSCCAP00000029371	ENSCCAP00000024527	DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.	Checkpoint kinase 1; Belongs to the protein kinase superfamily.	0.487
GINS4	GINS1	ENSCCAP00000029371	ENSCCAP00000033536	DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.	GINS complex subunit 1.	0.998
GINS4	NCAPG2	ENSCCAP00000029371	ENSCCAP00000033583	DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family.	Non-SMC condensin II complex subunit G2.	0.426
INTS1	CTR9	ENSCCAP00000015419	ENSCCAP00000040474	Integrator complex subunit 1.	CTR9 homolog, Paf1/RNA polymerase II complex component.	0.482
NBN	BRCA2	ENSCCAP00000031403	ENSCCAP00000031676	Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.	BRCA2 DNA repair associated.	0.801
NBN	CHEK1	ENSCCAP00000031403	ENSCCAP00000024527	Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.	Checkpoint kinase 1; Belongs to the protein kinase superfamily.	0.713
NBN	PALB2	ENSCCAP00000031403	ENSCCAP00000026053	Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.	Partner and localizer of BRCA2.	0.675
NBN	RAD51B	ENSCCAP00000031403	ENSCCAP00000009631	Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.	RAD51 paralog B.	0.746