STRINGSTRING
RIPK1 RIPK1 GAS6 GAS6 USP27X USP27X STING1 STING1 TXK TXK FADD FADD ENSCCAP00000040608 ENSCCAP00000040608 CSF1 CSF1 TRIM41 TRIM41 RNF185 RNF185 AGPAT2 AGPAT2 LOC108304488 LOC108304488 HIF1A HIF1A IRF7 IRF7 IKBKE IKBKE PARP14 PARP14 UBE2K UBE2K TRIM32 TRIM32 LOC108293547 LOC108293547 IL7 IL7 MMP12 MMP12 AGPAT1 AGPAT1 CD300LD CD300LD ADAM17 ADAM17 MAVS MAVS GFI1 GFI1 PARP9 PARP9 LSM14A LSM14A ENSCCAP00000038906 ENSCCAP00000038906 HPX HPX IL1R1 IL1R1 TRAF2 TRAF2 CD300LF CD300LF ENSCCAP00000018439 ENSCCAP00000018439 LOC108285006 LOC108285006 IRF3 IRF3 WNT5A WNT5A CD74 CD74 AXL AXL PRKN PRKN CASP1 CASP1 TRIM44 TRIM44 TBK1 TBK1 TSLP TSLP NLRC5 NLRC5 TREM2 TREM2 EDN1 EDN1 LOC108307367 LOC108307367 CXCR4 CXCR4 RIPK2 RIPK2 MED1 MED1 NLRP6 NLRP6 TRIM56 TRIM56 ZBP1 ZBP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RIPK1Receptor interacting serine/threonine kinase 1. (671 aa)
GAS6Growth arrest specific 6. (676 aa)
USP27XUbiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (438 aa)
STING1Transmembrane protein 173. (379 aa)
TXKTyrosine-protein kinase. (527 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
ENSCCAP00000040608Uncharacterized protein. (418 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (551 aa)
TRIM41Tripartite motif containing 41. (629 aa)
RNF185Ring finger protein 185. (192 aa)
AGPAT21-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (278 aa)
LOC108304488Uncharacterized protein. (455 aa)
HIF1AUncharacterized protein. (848 aa)
IRF7Interferon regulatory factor 7. (500 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa)
PARP14Poly [ADP-ribose] polymerase. (1792 aa)
UBE2KUncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
TRIM32Tripartite motif containing 32. (653 aa)
LOC108293547Uncharacterized protein. (773 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (177 aa)
MMP12Matrix metallopeptidase 12. (469 aa)
AGPAT11-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (285 aa)
CD300LDCD300 molecule like family member d. (174 aa)
ADAM17ADAM metallopeptidase domain 17. (914 aa)
MAVSMitochondrial antiviral signaling protein. (533 aa)
GFI1Growth factor independent 1 transcriptional repressor. (422 aa)
PARP9Poly(ADP-ribose) polymerase family member 9. (817 aa)
LSM14AUncharacterized protein. (441 aa)
ENSCCAP00000038906FFD domain-containing protein. (433 aa)
HPXHemopexin. (414 aa)
IL1R1Interleukin 1 receptor type 1. (569 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
CD300LFCD300 molecule like family member f. (305 aa)
ENSCCAP00000018439RING-type domain-containing protein. (639 aa)
LOC108285006Uncharacterized protein. (394 aa)
IRF3Interferon regulatory factor 3. (427 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
CD74CD74 molecule. (308 aa)
AXLAXL receptor tyrosine kinase. (896 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
CASP1Uncharacterized protein; Belongs to the peptidase C14A family. (439 aa)
TRIM44Tripartite motif containing 44. (344 aa)
TBK1TANK binding kinase 1. (729 aa)
TSLPThymic stromal lymphopoietin. (158 aa)
NLRC5NLR family CARD domain containing 5. (1868 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
EDN1Endothelin 1. (212 aa)
LOC108307367Uncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (405 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1517 aa)
NLRP6NLR family pyrin domain containing 6. (892 aa)
TRIM56Uncharacterized protein. (756 aa)
ZBP1Z-DNA binding protein 1. (428 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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