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| | MEIOB | Meiosis specific with OB-fold. (455 aa) |
| | RPA3 | Uncharacterized protein. (121 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | NUP35 | Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (326 aa) |
| | DDX11 | DEAD/H-box helicase 11. (957 aa) |
| | BIVM | XPGN domain-containing protein. (1597 aa) |
| | ENSCCAP00000005550 | Uncharacterized protein. (215 aa) |
| | LOC108301415 | Uncharacterized protein. (111 aa) |
| | ENSCCAP00000005932 | CSD_1 domain-containing protein. (285 aa) |
| | HNRNPDL | Heterogeneous nuclear ribonucleoprotein D like. (420 aa) |
| | SAMHD1 | SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (509 aa) |
| | TERF2IP | TERF2 interacting protein. (399 aa) |
| | PCBP3 | Poly(rC) binding protein 3. (371 aa) |
| | ENSCCAP00000013666 | CSP domain-containing protein. (313 aa) |
| | NABP1 | Nucleic acid binding protein 1. (123 aa) |
| | POLR3C | RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (534 aa) |
| | IGHMBP2 | Immunoglobulin mu DNA binding protein 2. (993 aa) |
| | REXO4 | REX4 homolog, 3'-5' exonuclease. (397 aa) |
| | LOC108313404 | CSD_1 domain-containing protein. (277 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (863 aa) |
| | ENSCCAP00000013616 | Uncharacterized protein. (120 aa) |
| | TSN | Translin. (228 aa) |
| | LONP1 | Lon protease homolog; Belongs to the peptidase S16 family. (858 aa) |
| | ENSCCAP00000016251 | Uncharacterized protein. (107 aa) |
| | LOC108290315 | CSD_1 domain-containing protein. (260 aa) |
| | RPA2 | Replication protein A2. (339 aa) |
| | POLA1 | DNA polymerase. (1391 aa) |
| | ENSCCAP00000010913 | SPRY domain-containing protein. (494 aa) |
| | FBH1 | F-box DNA helicase 1. (1080 aa) |
| | RAD51AP2 | RAD51 associated protein 2. (1155 aa) |
| | WBP11 | Uncharacterized protein. (641 aa) |
| | ENSCCAP00000013067 | Uncharacterized protein. (113 aa) |
| | ENSCCAP00000028238 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (422 aa) |
| | ENSCCAP00000028230 | Uncharacterized protein. (95 aa) |
| | LRPPRC | PPR_long domain-containing protein. (1395 aa) |
| | HROB | Chromosome 17 open reading frame 53. (636 aa) |
| | SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1. (1049 aa) |
| | TDP1 | Tyrosyl-DNA phosphodiesterase 1. (606 aa) |
| | NABP2 | Nucleic acid binding protein 2. (187 aa) |
| | RAD23A | RAD23 homolog A, nucleotide excision repair protein. (362 aa) |
| | TOP3A | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1001 aa) |
| | TOP1 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (767 aa) |
| | SSBP2 | Single stranded DNA binding protein 2. (361 aa) |
| | HNRNPU | Heterogeneous nuclear ribonucleoprotein U. (825 aa) |
| | MCM9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1139 aa) |
| | MCM10 | Minichromosome maintenance 10 replication initiation factor. (870 aa) |
| | HSF1 | Heat shock transcription factor 1. (532 aa) |
| | ENSCCAP00000022814 | Uncharacterized protein. (362 aa) |
| | HNRNPA2B1 | Heterogeneous nuclear ribonucleoprotein A2/B1. (353 aa) |
| | ENSCCAP00000022407 | Uncharacterized protein. (67 aa) |
| | SSBP1 | Uncharacterized protein. (148 aa) |
| | CRY2 | Cryptochrome circadian regulator 2. (614 aa) |
| | RAD54L | RAD54 like. (747 aa) |
| | ENSCCAP00000000393 | Uncharacterized protein. (145 aa) |
| | HMCES | Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (353 aa) |
| | ENSCCAP00000000938 | CSD_1 domain-containing protein. (286 aa) |
| | PURB | Purine rich element binding protein B. (312 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (557 aa) |
| | PCBP2 | Poly(rC) binding protein 2. (354 aa) |
| | ZRANB3 | Zinc finger RANBP2-type containing 3. (1080 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (904 aa) |
| | NUCKS1 | Nuclear casein kinase and cyclin dependent kinase substrate 1. (243 aa) |
| | CTC1 | CST telomere replication complex component 1. (1162 aa) |
| | ENSCCAP00000003694 | Uncharacterized protein. (127 aa) |
| | NEIL3 | Nei like DNA glycosylase 3. (606 aa) |
| | RBBP8 | RB binding protein 8, endonuclease. (899 aa) |
| | ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit. (298 aa) |
| | PCBP1 | Uncharacterized protein. (356 aa) |
| | ENSCCAP00000019805 | Uncharacterized protein. (54 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (709 aa) |
| | TERF2 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (527 aa) |
| | ENSCCAP00000037411 | Uncharacterized protein. (145 aa) |
| | FUBP1 | Far upstream element binding protein 1. (539 aa) |
| | RECQL | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (649 aa) |
| | RADX | RPA1 related single stranded DNA binding protein, X-linked. (855 aa) |
| | BLM | BLM RecQ like helicase. (1401 aa) |
| | TEN1 | Uncharacterized protein. (123 aa) |
| | RAD18 | RAD18 E3 ubiquitin protein ligase. (495 aa) |
| | SPRTN | SprT-like N-terminal domain. (487 aa) |
| | SMC4 | Structural maintenance of chromosomes protein. (1287 aa) |
| | TDP2 | Tyrosyl-DNA phosphodiesterase 2. (362 aa) |
| | SSBP4 | Single stranded DNA binding protein 4. (408 aa) |
| | MMS22L | MMS22 like, DNA repair protein. (1241 aa) |
| | TWNK | Twinkle mtDNA helicase. (684 aa) |
| | DMC1 | Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (311 aa) |
| | SSBP3 | Single stranded DNA binding protein 3. (388 aa) |
| | SMC6 | Structural maintenance of chromosomes 6. (1097 aa) |
| | XPC | XPC complex subunit, DNA damage recognition and repair factor. (938 aa) |
| | SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (957 aa) |
| | TERF1 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (376 aa) |
| | DHX9 | DExH-box helicase 9. (1136 aa) |
| | RAD51B | RAD51 paralog B. (426 aa) |
| | RAD51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa) |
| | SETMAR | SET domain and mariner transposase fusion gene. (684 aa) |
| | ENSCCAP00000040606 | Uncharacterized protein. (587 aa) |
| | LOC108282873 | Uncharacterized protein. (611 aa) |
| | RTF1 | RTF1 homolog, Paf1/RNA polymerase II complex component. (643 aa) |
| | SWSAP1 | SWIM-type zinc finger 7 associated protein 1. (248 aa) |
| | SMC5 | SMC_N domain-containing protein. (1102 aa) |
| | POU4F1 | POU domain protein. (404 aa) |
| | FUBP3 | Far upstream element binding protein 3. (572 aa) |
| | FAM111A | Uncharacterized protein. (610 aa) |
| | RAD52 | RAD52 homolog, DNA repair protein. (419 aa) |
| | WDR48 | WD repeat domain 48. (684 aa) |
| | RECQL4 | RecQ like helicase 4. (1211 aa) |
| | POT1 | Protection of telomeres 1. (666 aa) |
| | DHX36 | DEAH-box helicase 36. (1001 aa) |
| | POLR2H | DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa) |
| | ENSCCAP00000033750 | Uncharacterized protein. (178 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (734 aa) |
| | SMC2 | Structural maintenance of chromosomes protein. (1182 aa) |
| | MYEF2 | Myelin expression factor 2. (600 aa) |
| | ENSCCAP00000004768 | Uncharacterized protein. (143 aa) |
| | STN1 | CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (368 aa) |
| | BRCA2 | BRCA2 DNA repair associated. (3397 aa) |
| | RBMS1 | RNA binding motif single stranded interacting protein 1. (406 aa) |
| | ENSCCAP00000031489 | HTH myb-type domain-containing protein. (287 aa) |
| | RAD23B | RAD23 homolog B, nucleotide excision repair protein. (409 aa) |
| | YBX1 | CSD_1 domain-containing protein. (267 aa) |
| | ENSCCAP00000030858 | S1 domain-containing protein. (182 aa) |
| | ERCC4 | ERCC excision repair 4, endonuclease catalytic subunit. (916 aa) |
| | SHOC1 | Shortage in chiasmata 1. (1444 aa) |
| | RAD51AP1 | RAD51 associated protein 1. (350 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (395 aa) |
| | CDC45 | Cell division cycle 45. (594 aa) |
| | ENSCCAP00000015138 | TRF domain-containing protein. (250 aa) |
