STRINGSTRING
HDAC1 HDAC1 DRAP1 DRAP1 HNRNPU HNRNPU SF1 SF1 WTIP WTIP MTA1 MTA1 CTBP2 CTBP2 FHL2 FHL2 MED1 MED1 DNAJB1 DNAJB1 ENSCCAP00000001992 ENSCCAP00000001992 CBX4 CBX4 SAP30 SAP30 FOXP3 FOXP3 LOC108305078 LOC108305078 HSBP1 HSBP1 EZH2 EZH2 NRIP1 NRIP1 RERE RERE BCORL1 BCORL1 ENSCCAP00000003780 ENSCCAP00000003780 YAF2 YAF2 IRF2BP1 IRF2BP1 ENSCCAP00000003927 ENSCCAP00000003927 RB1 RB1 EID2 EID2 RBBP8 RBBP8 URI1 URI1 CITED2 CITED2 SPEN SPEN DNMT3B DNMT3B ENSCCAP00000005312 ENSCCAP00000005312 ENSCCAP00000005634 ENSCCAP00000005634 SSX1 SSX1 LOC108298753 LOC108298753 CCAR1 CCAR1 PEX14 PEX14 LMCD1 LMCD1 HDAC9 HDAC9 RCOR1 RCOR1 PBXIP1 PBXIP1 ZNF366 ZNF366 ATF7IP ATF7IP CDYL CDYL RLIM RLIM MIER2 MIER2 BTG2 BTG2 ENSCCAP00000007739 ENSCCAP00000007739 SIRT6 SIRT6 DMAP1 DMAP1 SIN3B SIN3B ENSCCAP00000008477 ENSCCAP00000008477 MIER3 MIER3 ELANE ELANE ENSCCAP00000009349 ENSCCAP00000009349 SMYD1 SMYD1 GPS2 GPS2 TLE3 TLE3 DDX54 DDX54 ENSCCAP00000009946 ENSCCAP00000009946 LOC108294454 LOC108294454 TDP2 TDP2 LCOR LCOR C1QBP C1QBP ENSCCAP00000010913 ENSCCAP00000010913 WNT4 WNT4 ENSCCAP00000011029 ENSCCAP00000011029 HDAC3 HDAC3 SFMBT1 SFMBT1 BRD7 BRD7 BCL3 BCL3 HSBP1L1 HSBP1L1 MLIP MLIP CASP8AP2 CASP8AP2 MAP3K10 MAP3K10 LOC108284316 LOC108284316 ENSCCAP00000013277 ENSCCAP00000013277 TCF25 TCF25 PRKN PRKN PARP10 PARP10 SUFU SUFU HMGA2 HMGA2 RUVBL2 RUVBL2 ENSCCAP00000015162 ENSCCAP00000015162 RUNX1T1 RUNX1T1 RYBP RYBP PIAS1 PIAS1 HIRA HIRA CREBBP CREBBP JAZF1 JAZF1 MYBBP1A MYBBP1A TBL1X TBL1X NPAT NPAT MTA2 MTA2 FAM162A FAM162A NCOR2 NCOR2 YY1AP1 YY1AP1 SIN3A SIN3A TRIB3 TRIB3 ZNF653 ZNF653 LIMD1 LIMD1 PHF12 PHF12 LOC108297905 LOC108297905 AASS AASS CCND1 CCND1 LOC108297229 LOC108297229 RCOR3 RCOR3 CYS1 CYS1 TCERG1 TCERG1 PARP14 PARP14 ENSCCAP00000022660 ENSCCAP00000022660 BCOR BCOR CREG1 CREG1 CDYL2 CDYL2 SIRT1 SIRT1 KDM5B KDM5B ENSCCAP00000023859 ENSCCAP00000023859 ATN1 ATN1 DPF2 DPF2 TLE7 TLE7 ENSCCAP00000024577 ENSCCAP00000024577 ENSCCAP00000024758 ENSCCAP00000024758 RIOX2 RIOX2 CBFA2T2 CBFA2T2 NCOA5 NCOA5 TLE1 TLE1 CIR1 CIR1 TRIM28 TRIM28 PA2G4 PA2G4 CRYM CRYM NR0B2 NR0B2 ENSCCAP00000025868 ENSCCAP00000025868 ANKRD1 ANKRD1 ARID5A ARID5A FAM162B FAM162B TLE2 TLE2 NSD1 NSD1 PIAS4 PIAS4 PHB PHB LOC108303397 LOC108303397 ZNF451 ZNF451 ZFPM2 ZFPM2 ENSCCAP00000027427 ENSCCAP00000027427 SCAI SCAI ENSCCAP00000027802 ENSCCAP00000027802 HDGF HDGF TBL1XR1 TBL1XR1 CNOT7 CNOT7 SIAH2 SIAH2 NR0B1 NR0B1 SMARCA4 SMARCA4 SDR16C5 SDR16C5 SFMBT2 SFMBT2 ENSCCAP00000029990 ENSCCAP00000029990 WWTR1 WWTR1 NCOR1 NCOR1 PPP1R13L PPP1R13L KMT5A KMT5A UXT UXT TLE4 TLE4 IRF2BP2 IRF2BP2 SNW1 SNW1 COPS2 COPS2 RCOR2 RCOR2 GMNN GMNN MTA3 MTA3 HIPK2 HIPK2 NAB2 NAB2 NOC2L NOC2L YAP1 YAP1 ENSCCAP00000034142 ENSCCAP00000034142 SIRT7 SIRT7 ZMYND8 ZMYND8 PRMT5 PRMT5 TLE6 TLE6 BEND6 BEND6 DAXX DAXX HDAC7 HDAC7 CBFA2T3 CBFA2T3 AJUBA AJUBA ZMYND11 ZMYND11 TSG101 TSG101 ZFPM1 ZFPM1 ENSCCAP00000036999 ENSCCAP00000036999 TFAP2A TFAP2A RBFOX2 RBFOX2 N4BP2L2 N4BP2L2 LOC108282374 LOC108282374 PARP9 PARP9 CTBP1 CTBP1 ELMSAN1 ELMSAN1 GON4L GON4L TLE5 TLE5 MECP2 MECP2 TRERF1 TRERF1 PARP15 PARP15 DNMT3A DNMT3A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
DRAP1DR1 associated protein 1. (205 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (825 aa)
SF1Splicing factor 1. (673 aa)
WTIPWT1 interacting protein. (429 aa)
MTA1Metastasis associated 1. (743 aa)
CTBP2C-terminal binding protein 2. (927 aa)
FHL2Four and a half LIM domains 2. (378 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1517 aa)
DNAJB1DnaJ heat shock protein family (Hsp40) member B1. (340 aa)
ENSCCAP00000001992Uncharacterized protein. (123 aa)
CBX4Chromobox 4. (558 aa)
SAP30Sin3A associated protein 30. (220 aa)
FOXP3Forkhead box P3. (454 aa)
LOC108305078Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (407 aa)
HSBP1Heat shock factor binding protein 1. (76 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa)
NRIP1Nuclear receptor interacting protein 1. (1158 aa)
REREArginine-glutamic acid dipeptide repeats. (1558 aa)
BCORL1BCL6 corepressor like 1. (1709 aa)
ENSCCAP00000003780Prohibitin. (198 aa)
YAF2YY1 associated factor 2. (204 aa)
IRF2BP1Interferon regulatory factor 2 binding protein 1. (584 aa)
ENSCCAP00000003927Uncharacterized protein. (618 aa)
RB1RB transcriptional corepressor 1. (927 aa)
EID2EP300 interacting inhibitor of differentiation 2. (228 aa)
RBBP8RB binding protein 8, endonuclease. (899 aa)
URI1URI1 prefoldin like chaperone. (556 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (275 aa)
SPENSpen family transcriptional repressor. (3569 aa)
DNMT3BUncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (853 aa)
ENSCCAP00000005312Uncharacterized protein. (236 aa)
ENSCCAP00000005634Hist_deacetyl domain-containing protein. (305 aa)
SSX1SSX family member 1. (212 aa)
LOC108298753Uncharacterized protein. (242 aa)
CCAR1Cell division cycle and apoptosis regulator 1. (1150 aa)
PEX14Pex14_N domain-containing protein. (377 aa)
LMCD1LIM and cysteine rich domains 1. (368 aa)
HDAC9Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1069 aa)
RCOR1REST corepressor 1. (490 aa)
PBXIP1PBX homeobox interacting protein 1. (730 aa)
ZNF366Zinc finger protein 366. (743 aa)
ATF7IPActivating transcription factor 7 interacting protein. (1282 aa)
CDYLChromodomain Y like. (594 aa)
RLIMRing finger protein, LIM domain interacting. (620 aa)
MIER2MIER family member 2. (546 aa)
BTG2BTG anti-proliferation factor 2. (158 aa)
ENSCCAP00000007739Uncharacterized protein. (279 aa)
SIRT6Sirtuin 6. (382 aa)
DMAP1DNA methyltransferase 1 associated protein 1. (467 aa)
SIN3BSIN3 transcription regulator family member B. (1134 aa)
ENSCCAP00000008477Bromo domain-containing protein. (549 aa)
MIER3MIER family member 3. (550 aa)
ELANEElastase, neutrophil expressed; Belongs to the peptidase S1 family. (265 aa)
ENSCCAP00000009349SKIP_SNW domain-containing protein. (447 aa)
SMYD1SET and MYND domain containing 1. (490 aa)
GPS2G protein pathway suppressor 2. (327 aa)
TLE3TLE family member 3, transcriptional corepressor. (786 aa)
DDX54ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (878 aa)
ENSCCAP00000009946PWWP domain-containing protein. (368 aa)
LOC108294454Prohibitin. (262 aa)
TDP2Tyrosyl-DNA phosphodiesterase 2. (362 aa)
LCORLigand dependent nuclear receptor corepressor. (1693 aa)
C1QBPComplement C1q binding protein. (284 aa)
ENSCCAP00000010913SPRY domain-containing protein. (494 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
ENSCCAP00000011029Uncharacterized protein. (286 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
SFMBT1Scm like with four mbt domains 1. (866 aa)
BRD7Bromo domain-containing protein. (652 aa)
BCL3BCL3 transcription coactivator. (454 aa)
HSBP1L1Heat shock factor binding protein 1 like 1. (74 aa)
MLIPMuscular LMNA interacting protein. (994 aa)
CASP8AP2Caspase 8 associated protein 2. (1976 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase. (952 aa)
LOC108284316Uncharacterized protein. (206 aa)
ENSCCAP00000013277SET domain-containing protein. (273 aa)
TCF25Transcription factor 25. (631 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
PARP10Poly [ADP-ribose] polymerase. (1005 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (522 aa)
HMGA2Uncharacterized protein. (118 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (468 aa)
ENSCCAP00000015162Peptidase_M24 domain-containing protein. (165 aa)
RUNX1T1RUNX1 partner transcriptional co-repressor 1. (662 aa)
RYBPRING1 and YY1 binding protein. (228 aa)
PIAS1Protein inhibitor of activated STAT 1. (653 aa)
HIRAProtein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1017 aa)
CREBBPCREB binding protein. (2448 aa)
JAZF1JAZF zinc finger 1. (243 aa)
MYBBP1AMYB binding protein 1a. (1321 aa)
TBL1XTransducin beta like 1 X-linked. (517 aa)
NPATNuclear protein, coactivator of histone transcription. (1425 aa)
MTA2Metastasis associated 1 family member 2. (668 aa)
FAM162AFamily with sequence similarity 162 member A. (155 aa)
NCOR2Nuclear receptor corepressor 2. (2513 aa)
YY1AP1YY1 associated protein 1. (817 aa)
SIN3ASIN3 transcription regulator family member A. (1273 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
ZNF653Zinc finger protein 653. (612 aa)
LIMD1LIM domains containing 1. (676 aa)
PHF12PHD finger protein 12. (1004 aa)
LOC108297905Uncharacterized protein. (791 aa)
AASSUncharacterized protein. (451 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (295 aa)
LOC108297229Uncharacterized protein. (518 aa)
RCOR3REST corepressor 3. (480 aa)
CYS1Cystin 1. (154 aa)
TCERG1Transcription elongation regulator 1. (1016 aa)
PARP14Poly [ADP-ribose] polymerase. (1792 aa)
ENSCCAP00000022660Uncharacterized protein. (404 aa)
BCORBCL6 corepressor. (1707 aa)
CREG1Cellular repressor of E1A stimulated genes 1; Belongs to the CREG family. (220 aa)
CDYL2Chromodomain Y like 2. (507 aa)
SIRT1Sirtuin 1. (446 aa)
KDM5BLysine demethylase 5B. (1516 aa)
ENSCCAP00000023859Uncharacterized protein. (102 aa)
ATN1Atrophin 1. (1183 aa)
DPF2Double PHD fingers 2. (405 aa)
TLE7TLE family member 7. (441 aa)
ENSCCAP00000024577Prohibitin. (247 aa)
ENSCCAP00000024758Pex14_N domain-containing protein. (110 aa)
RIOX2Bifunctional lysine-specific demethylase and histidyl-hydroxylase; Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. (465 aa)
CBFA2T2CBFA2/RUNX1 partner transcriptional co-repressor 2. (614 aa)
NCOA5Nuclear receptor coactivator 5. (579 aa)
TLE1TLE family member 1, transcriptional corepressor. (779 aa)
CIR1Corepressor interacting with RBPJ, 1. (431 aa)
TRIM28Tripartite motif containing 28. (834 aa)
PA2G4Peptidase_M24 domain-containing protein. (383 aa)
CRYMCrystallin mu. (314 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (257 aa)
ENSCCAP00000025868Bromo domain-containing protein. (550 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
ARID5AAT-rich interaction domain 5A. (594 aa)
FAM162BFamily with sequence similarity 162 member B. (162 aa)
TLE2TLE family member 2, transcriptional corepressor. (691 aa)
NSD1Nuclear receptor binding SET domain protein 1. (2593 aa)
PIAS4Protein inhibitor of activated STAT 4. (543 aa)
PHBProhibitin. (272 aa)
LOC108303397Prohibitin. (244 aa)
ZNF451Zinc finger protein 451. (1061 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1151 aa)
ENSCCAP00000027427Uncharacterized protein. (202 aa)
SCAIProtein SCAI; Tumor suppressor which functions to suppress MRTFA-induced SRF transcriptional activity. (618 aa)
ENSCCAP00000027802Uncharacterized protein. (164 aa)
HDGFHeparin binding growth factor. (256 aa)
TBL1XR1Transducin beta like 1 X-linked receptor 1. (514 aa)
CNOT7Uncharacterized protein. (285 aa)
SIAH2E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (324 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (470 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1642 aa)
SDR16C5Short chain dehydrogenase/reductase family 16C member 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (309 aa)
SFMBT2Scm like with four mbt domains 2. (894 aa)
ENSCCAP00000029990Prohibitin. (223 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
NCOR1SANT domain-containing protein. (2281 aa)
PPP1R13LProtein phosphatase 1 regulatory subunit 13 like. (830 aa)
KMT5ALysine methyltransferase 5A. (347 aa)
UXTUbiquitously expressed prefoldin like chaperone. (157 aa)
TLE4TLE family member 4, transcriptional corepressor. (792 aa)
IRF2BP2Interferon regulatory factor 2 binding protein 2. (587 aa)
SNW1SNW domain containing 1. (570 aa)
COPS2COP9 signalosome subunit 2. (450 aa)
RCOR2REST corepressor 2. (523 aa)
GMNNGeminin DNA replication inhibitor. (209 aa)
MTA3Metastasis associated 1 family member 3. (594 aa)
HIPK2Homeodomain interacting protein kinase 2. (1189 aa)
NAB2NGFI-A binding protein 2. (525 aa)
NOC2LNOC2 like nucleolar associated transcriptional repressor. (746 aa)
YAP1Uncharacterized protein. (506 aa)
ENSCCAP00000034142Peptidase_M24 domain-containing protein. (328 aa)
SIRT7Sirtuin 7. (421 aa)
ZMYND8Zinc finger MYND-type containing 8. (1244 aa)
PRMT5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (637 aa)
TLE6TLE family member 6, subcortical maternal complex member. (569 aa)
BEND6BEN domain containing 6. (279 aa)
DAXXDaxx domain-containing protein. (750 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1004 aa)
CBFA2T3Uncharacterized protein. (653 aa)
AJUBAAjuba LIM protein. (539 aa)
ZMYND11Zinc finger MYND-type containing 11. (602 aa)
TSG101Tumor susceptibility 101. (395 aa)
ZFPM1Zinc finger protein, FOG family member 1. (1001 aa)
ENSCCAP00000036999Bromo domain-containing protein. (546 aa)
TFAP2ATranscription factor AP-2 alpha. (439 aa)
RBFOX2RNA binding fox-1 homolog 2. (451 aa)
N4BP2L2NEDD4 binding protein 2 like 2. (750 aa)
LOC108282374Uncharacterized protein. (330 aa)
PARP9Poly(ADP-ribose) polymerase family member 9. (817 aa)
CTBP1C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (458 aa)
ELMSAN1ELM2 and Myb/SANT domain containing 1. (1106 aa)
GON4LGon-4 like. (2230 aa)
TLE5TLE family member 5, transcriptional modulator. (248 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
TRERF1Transcriptional regulating factor 1. (1216 aa)
PARP15Poly [ADP-ribose] polymerase. (658 aa)
DNMT3ADNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (912 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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