STRINGSTRING
APLF APLF NEIL3 NEIL3 RPS3 RPS3 ENSCCAP00000005370 ENSCCAP00000005370 NTHL1 NTHL1 ENSCCAP00000010734 ENSCCAP00000010734 HMGA1 HMGA1 HMGA2 HMGA2 NEIL1 NEIL1 LOC108291481 LOC108291481 NEIL2 NEIL2 LOC108288088 LOC108288088 APEX1 APEX1 POLB POLB OGG1 OGG1 ALKBH1 ALKBH1 LOC108300644 LOC108300644
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APLFAprataxin and PNKP like factor. (502 aa)
NEIL3Nei like DNA glycosylase 3. (606 aa)
RPS3Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (270 aa)
ENSCCAP00000005370Uncharacterized protein. (97 aa)
NTHL1Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (312 aa)
ENSCCAP00000010734Uncharacterized protein; Belongs to the universal ribosomal protein uS3 family. (216 aa)
HMGA1High mobility group AT-hook 1. (107 aa)
HMGA2Uncharacterized protein. (118 aa)
NEIL1Nei like DNA glycosylase 1. (390 aa)
LOC108291481DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (465 aa)
NEIL2Nei like DNA glycosylase 2. (326 aa)
LOC108288088DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (305 aa)
APEX1DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (318 aa)
POLBDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa)
OGG18-oxoguanine DNA glycosylase. (402 aa)
ALKBH1AlkB homolog 1, histone H2A dioxygenase. (389 aa)
LOC108300644KH type-2 domain-containing protein. (261 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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