STRINGSTRING
ENSCCAP00000000077 ENSCCAP00000000077 HOOK2 HOOK2 EXT1 EXT1 NAGLU NAGLU HOOK1 HOOK1 ARL8A ARL8A CXorf21 CXorf21 ATG16L1 ATG16L1 STBD1 STBD1 STX17 STX17 LOC108288609 LOC108288609 STING1 STING1 UBQLN2 UBQLN2 MAP1LC3C MAP1LC3C MAN2A1 MAN2A1 LYST LYST EMC6 EMC6 RAB33B RAB33B ATG9A ATG9A WIPI2 WIPI2 PIK3C3 PIK3C3 RAB23 RAB23 ATG101 ATG101 GABARAPL2 GABARAPL2 ATG3 ATG3 ENSCCAP00000006696 ENSCCAP00000006696 ULK3 ULK3 ENSCCAP00000007309 ENSCCAP00000007309 RAB1A RAB1A ENSCCAP00000008313 ENSCCAP00000008313 LRRK2 LRRK2 TMEM130 TMEM130 CORO1A CORO1A LOC108299308 LOC108299308 ATG12 ATG12 ENSCCAP00000008966 ENSCCAP00000008966 ATG5 ATG5 RB1CC1 RB1CC1 ACP2 ACP2 ARFIP2 ARFIP2 CLVS1 CLVS1 HPS4 HPS4 HEXA HEXA MAP1LC3B MAP1LC3B STX12 STX12 LOC108305632 LOC108305632 VPS33B VPS33B LOC108289348 LOC108289348 ATP6AP2 ATP6AP2 RAB43 RAB43 AP3B1 AP3B1 ENSCCAP00000013099 ENSCCAP00000013099 SNAPIN SNAPIN FIG4 FIG4 VMP1 VMP1 CHMP4C CHMP4C VPS18 VPS18 ULK1 ULK1 SRPX SRPX TMEM199 TMEM199 PIK3C2B PIK3C2B NSFL1C NSFL1C HEXB HEXB UBXN2A UBXN2A TP53INP1 TP53INP1 LOC108310106 LOC108310106 AP4M1 AP4M1 CCDC115 CCDC115 ARSB ARSB ATG2B ATG2B PLA2G5 PLA2G5 MBTPS1 MBTPS1 ATP6V0B ATP6V0B EPM2A EPM2A WDR45 WDR45 ATP6AP1 ATP6AP1 MFN2 MFN2 PIKFYVE PIKFYVE MAP1LC3A MAP1LC3A NAGPA NAGPA LOC108286132 LOC108286132 CHMP5 CHMP5 VPS35 VPS35 TMEM106B TMEM106B LAPTM5 LAPTM5 ATP6V1H ATP6V1H GBA GBA HPS1 HPS1 ATP10B ATP10B MTOR MTOR VPS16 VPS16 CLN8 CLN8 ARL8B ARL8B RNASEK RNASEK ATG14 ATG14 ATG4D ATG4D RAB39A RAB39A MT3 MT3 TP53INP2 TP53INP2 WIPI1 WIPI1 LAPTM4A LAPTM4A RAB19 RAB19 TMEM41B TMEM41B ATG4B ATG4B ENSCCAP00000023312 ENSCCAP00000023312 ATP13A2 ATP13A2 CLN5 CLN5 KIAA1324 KIAA1324 ENSCCAP00000023950 ENSCCAP00000023950 UBXN2B UBXN2B GNPTAB GNPTAB ATG9B ATG9B TCIRG1 TCIRG1 ACPP ACPP HOOK3 HOOK3 MFSD8 MFSD8 LAMTOR1 LAMTOR1 ENSCCAP00000027403 ENSCCAP00000027403 TMEM165 TMEM165 RASEF RASEF ENSCCAP00000028878 ENSCCAP00000028878 FAM160A2 FAM160A2 TMEM175 TMEM175 ATG13 ATG13 CLN6 CLN6 ENSCCAP00000031066 ENSCCAP00000031066 RAB7B RAB7B LRBA LRBA TMEM9 TMEM9 RAB20 RAB20 WDR45B WDR45B TRAPPC8 TRAPPC8 ATP2A2 ATP2A2 AKTIP AKTIP ATG2A ATG2A RAB34 RAB34 GRN GRN ATP6V1F ATP6V1F SYNPO2 SYNPO2 LOC108295942 LOC108295942 CHMP2A CHMP2A ZKSCAN3 ZKSCAN3 ATG7 ATG7 TPCN2 TPCN2 BECN1 BECN1 CHMP4B CHMP4B CLVS2 CLVS2 VIPAS39 VIPAS39 ATP6V0C ATP6V0C MYO7A MYO7A SPG11 SPG11 ATF2 ATF2 VPS33A VPS33A RAB7A RAB7A SYT7 SYT7 CLN3 CLN3 ATG16L2 ATG16L2 VPS4A VPS4A AMBRA1 AMBRA1 PPT1 PPT1 TFEB TFEB RUFY4 RUFY4 TPP1 TPP1 PSEN1 PSEN1 ZFYVE26 ZFYVE26 PACS2 PACS2 ULK2 ULK2 VPS11 VPS11 ACP4 ACP4 BAG3 BAG3 SMURF1 SMURF1 ABCA1 ABCA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSCCAP00000000077Uncharacterized protein. (56 aa)
HOOK2Hook microtubule tethering protein 2. (719 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
NAGLUN-acetyl-alpha-glucosaminidase. (742 aa)
HOOK1Hook microtubule tethering protein 1. (729 aa)
ARL8AADP ribosylation factor like GTPase 8A; Belongs to the small GTPase superfamily. Arf family. (186 aa)
CXorf21Chromosome X open reading frame 21. (298 aa)
ATG16L1Autophagy related 16 like 1. (624 aa)
STBD1Starch binding domain 1. (355 aa)
STX17Syntaxin 17; Belongs to the syntaxin family. (302 aa)
LOC108288609Uncharacterized protein. (226 aa)
STING1Transmembrane protein 173. (379 aa)
UBQLN2Ubiquilin 2. (624 aa)
MAP1LC3CMicrotubule associated protein 1 light chain 3 gamma. (147 aa)
MAN2A1Alpha-mannosidase. (1144 aa)
LYSTLysosomal trafficking regulator. (3802 aa)
EMC6ER membrane protein complex subunit 6. (110 aa)
RAB33BRAB33B, member RAS oncogene family. (229 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (839 aa)
WIPI2WD repeat domain, phosphoinositide interacting 2. (456 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
RAB23RAB23, member RAS oncogene family. (237 aa)
ATG101Autophagy related 101. (218 aa)
GABARAPL2GABA type A receptor associated protein like 2. (117 aa)
ATG3Autophagy-related protein 3. (307 aa)
ENSCCAP00000006696Uncharacterized protein. (201 aa)
ULK3Unc-51 like kinase 3. (480 aa)
ENSCCAP00000007309Uncharacterized protein. (70 aa)
RAB1ARAB1A, member RAS oncogene family. (205 aa)
ENSCCAP00000008313Vps16_C domain-containing protein. (451 aa)
LRRK2Leucine rich repeat kinase 2. (2526 aa)
TMEM130Transmembrane protein 130. (435 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
LOC108299308Uncharacterized protein. (83 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
ENSCCAP00000008966Uncharacterized protein. (183 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
RB1CC1RB1 inducible coiled-coil 1. (1594 aa)
ACP2Acid phosphatase 2, lysosomal; Belongs to the histidine acid phosphatase family. (423 aa)
ARFIP2ADP ribosylation factor interacting protein 2. (373 aa)
CLVS1Clavesin 1. (354 aa)
HPS4HPS4 biogenesis of lysosomal organelles complex 3 subunit 2. (708 aa)
HEXABeta-hexosaminidase. (529 aa)
MAP1LC3BUncharacterized protein. (102 aa)
STX12Syntaxin 12; Belongs to the syntaxin family. (330 aa)
LOC108305632V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (174 aa)
VPS33BUncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (595 aa)
LOC108289348CRAL-TRIO domain-containing protein. (139 aa)
ATP6AP2ATPase H+ transporting accessory protein 2. (350 aa)
RAB43RAB43, member RAS oncogene family. (212 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa)
ENSCCAP00000013099Uncharacterized protein. (83 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
FIG4FIG4 phosphoinositide 5-phosphatase. (907 aa)
VMP1Vacuole membrane protein 1. (421 aa)
CHMP4CCharged multivesicular body protein 4C. (233 aa)
VPS18VPS18 core subunit of CORVET and HOPS complexes. (973 aa)
ULK1Unc-51 like autophagy activating kinase 1. (964 aa)
SRPXSushi repeat containing protein X-linked. (450 aa)
TMEM199Transmembrane protein 199. (208 aa)
PIK3C2BPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1634 aa)
NSFL1CNSFL1 cofactor. (372 aa)
HEXBBeta-hexosaminidase. (553 aa)
UBXN2AUBX domain protein 2A. (254 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (241 aa)
LOC108310106Autophagy-related protein 3. (302 aa)
AP4M1AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] (453 aa)
CCDC115Coiled-coil domain containing 115. (180 aa)
ARSBArylsulfatase B. (534 aa)
ATG2BAutophagy related 2B. (2079 aa)
PLA2G5Phospholipase A(2). (138 aa)
MBTPS1Membrane bound transcription factor peptidase, site 1. (1052 aa)
ATP6V0BATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (261 aa)
EPM2AEPM2A glucan phosphatase, laforin. (331 aa)
WDR45Uncharacterized protein. (361 aa)
ATP6AP1ATPase H+ transporting accessory protein 1. (468 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2098 aa)
MAP1LC3AMicrotubule associated protein 1 light chain 3 alpha. (122 aa)
NAGPAN-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase. (515 aa)
LOC108286132Uncharacterized protein. (114 aa)
CHMP5Uncharacterized protein. (219 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (802 aa)
TMEM106BTransmembrane protein 106B. (274 aa)
LAPTM5Lysosomal protein transmembrane 5. (262 aa)
ATP6V1HV-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (483 aa)
GBAGlucosylceramidase. (536 aa)
HPS1HPS1 biogenesis of lysosomal organelles complex 3 subunit 1. (700 aa)
ATP10BPhospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1263 aa)
MTORSerine/threonine-protein kinase mTOR. (2508 aa)
VPS16Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (848 aa)
CLN8CLN8 transmembrane ER and ERGIC protein. (286 aa)
ARL8BADP ribosylation factor like GTPase 8B; Belongs to the small GTPase superfamily. Arf family. (186 aa)
RNASEKUncharacterized protein. (137 aa)
ATG14Autophagy related 14. (510 aa)
ATG4DCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (496 aa)
RAB39ARAB39A, member RAS oncogene family. (217 aa)
MT3Metallothionein 3; Belongs to the metallothionein superfamily. Type 1 family. (113 aa)
TP53INP2Tumor protein p53 inducible nuclear protein 2. (220 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (446 aa)
LAPTM4ALysosomal protein transmembrane 4 alpha. (233 aa)
RAB19RAB19, member RAS oncogene family. (217 aa)
TMEM41BTransmembrane protein 41B. (291 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (394 aa)
ENSCCAP00000023312Uncharacterized protein. (125 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1204 aa)
CLN5Uncharacterized protein. (389 aa)
KIAA1324KIAA1324. (927 aa)
ENSCCAP00000023950Uncharacterized protein. (154 aa)
UBXN2BUBX domain protein 2B. (331 aa)
GNPTABN-acetylglucosamine-1-phosphate transferase subunits alpha and beta. (1247 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (921 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (829 aa)
ACPPAcid phosphatase, prostate; Belongs to the histidine acid phosphatase family. (418 aa)
HOOK3Hook microtubule tethering protein 3. (747 aa)
MFSD8Major facilitator superfamily domain containing 8. (560 aa)
LAMTOR1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa)
ENSCCAP00000027403Uncharacterized protein. (161 aa)
TMEM165GDT1 family protein. (324 aa)
RASEFRAS and EF-hand domain containing. (740 aa)
ENSCCAP00000028878Uncharacterized protein. (111 aa)
FAM160A2Family with sequence similarity 160 member A2. (986 aa)
TMEM175Transmembrane protein 175. (504 aa)
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (527 aa)
CLN6CLN6 transmembrane ER protein. (340 aa)
ENSCCAP00000031066Uncharacterized protein. (379 aa)
RAB7BRAB7B, member RAS oncogene family. (199 aa)
LRBALPS responsive beige-like anchor protein. (2841 aa)
TMEM9Transmembrane protein 9. (183 aa)
RAB20RAB20, member RAS oncogene family. (234 aa)
WDR45BWD repeat domain 45B. (344 aa)
TRAPPC8Trafficking protein particle complex 8. (1435 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
AKTIPAKT interacting protein. (293 aa)
ATG2AAutophagy related 2A. (1941 aa)
RAB34RAB34, member RAS oncogene family. (259 aa)
GRNGranulin precursor. (595 aa)
ATP6V1FV-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (147 aa)
SYNPO2Synaptopodin 2. (1245 aa)
LOC108295942Autophagy-related protein 3. (310 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
ZKSCAN3Zinc finger with KRAB and SCAN domains 3. (532 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (707 aa)
TPCN2Uncharacterized protein. (730 aa)
BECN1Beclin 1. (450 aa)
CHMP4BCharged multivesicular body protein 4B. (224 aa)
CLVS2CRAL_TRIO_N domain-containing protein. (219 aa)
VIPAS39Vps16_C domain-containing protein. (505 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
MYO7AMyosin VIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2166 aa)
SPG11SPG11 vesicle trafficking associated, spatacsin. (2387 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
VPS33AUncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (577 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
SYT7Synaptotagmin 7. (686 aa)
CLN3Battenin. (491 aa)
ATG16L2Autophagy related 16 like 2. (619 aa)
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1298 aa)
PPT1Palmitoyl-protein thioesterase 1. (306 aa)
TFEBTranscription factor EB. (505 aa)
RUFY4RUN and FYVE domain containing 4. (501 aa)
TPP1Tripeptidyl peptidase 1. (572 aa)
PSEN1Presenilin 1. (419 aa)
ZFYVE26Zinc finger FYVE-type containing 26. (2542 aa)
PACS2Phosphofurin acidic cluster sorting protein 2. (904 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1022 aa)
VPS11Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (941 aa)
ACP4Acid phosphatase 4; Belongs to the histidine acid phosphatase family. (425 aa)
BAG3BCL2 associated athanogene 3. (576 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
ABCA1ATP binding cassette subfamily A member 1. (2258 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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