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ATIC | MGS domain-containing protein. (557 aa) | ||||
LOC108293271 | Protein kinase domain-containing protein. (158 aa) | ||||
LOC108306195 | MGS domain-containing protein. (593 aa) | ||||
ADSL | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (498 aa) | ||||
ADSS2 | Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (456 aa) | ||||
ENSCCAP00000005127 | A_deaminase domain-containing protein. (260 aa) | ||||
DLG1 | Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (926 aa) | ||||
NT5C1A | 5'-nucleotidase, cytosolic IA. (371 aa) | ||||
AMPD1 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (775 aa) | ||||
ENSCCAP00000006951 | Uncharacterized protein; Belongs to the adenylate kinase family. (186 aa) | ||||
IMPDH1 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (626 aa) | ||||
NT5E | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (574 aa) | ||||
GDA | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (472 aa) | ||||
IMPDH2 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. (514 aa) | ||||
PAICS | AIRC domain-containing protein. (453 aa) | ||||
XDH | Xanthine dehydrogenase. (1333 aa) | ||||
GMPR2 | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (358 aa) | ||||
GUK1 | Guanylate kinase 1. (235 aa) | ||||
LOC108310960 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (428 aa) | ||||
LOC108308296 | Adenylate kinase 2, mitochondrial; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis. (232 aa) | ||||
CASK | Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (510 aa) | ||||
HPRT1 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa) | ||||
APRT | Adenine phosphoribosyltransferase. (180 aa) | ||||
MAGI3 | Membrane associated guanylate kinase, WW and PDZ domain containing 3. (1483 aa) | ||||
GMPS | Uncharacterized protein. (693 aa) | ||||
NT5C | 5', 3'-nucleotidase, cytosolic. (201 aa) | ||||
AMPD3 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (777 aa) | ||||
ADA | A_deaminase domain-containing protein. (363 aa) | ||||
AK2 | ADK_lid domain-containing protein; Belongs to the adenylate kinase family. (201 aa) | ||||
LOC108292926 | MGS domain-containing protein. (536 aa) | ||||
AMPD2 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (880 aa) | ||||
PFAS | Phosphoribosylformylglycinamidine synthase. (1276 aa) | ||||
PNP | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa) | ||||
AK9 | Adenylate kinase 9. (1905 aa) | ||||
AK4 | Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (223 aa) | ||||
NT5C2 | 5'-nucleotidase, cytosolic II. (558 aa) | ||||
ENSCCAP00000016083 | GMP_synt_C domain-containing protein. (198 aa) | ||||
DLG2 | Discs large MAGUK scaffold protein 2. (961 aa) | ||||
CARD11 | Caspase recruitment domain family member 11. (1156 aa) | ||||
NUDT2 | Nudix hydrolase 2. (147 aa) | ||||
NT5DC1 | 5'-nucleotidase domain containing 1. (455 aa) | ||||
GART | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. (874 aa) | ||||
AK3 | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (227 aa) | ||||
LOC108308844 | ADK_lid domain-containing protein; Belongs to the adenylate kinase family. (231 aa) | ||||
LRGUK | Leucine rich repeats and guanylate kinase domain containing. (826 aa) | ||||
ADK | Adenosine kinase. (362 aa) | ||||
PPAT | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (514 aa) | ||||
ADSS1 | Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (457 aa) |