STRINGSTRING
BMP4 BMP4 ENSCCAP00000000807 ENSCCAP00000000807 ENSCCAP00000000866 ENSCCAP00000000866 JAG1 JAG1 OLFM1 OLFM1 LRG1 LRG1 BMP2 BMP2 EZH2 EZH2 GLIPR2 GLIPR2 ISL1 ISL1 SMAD3 SMAD3 COL1A1 COL1A1 LOC108292702 LOC108292702 PDPN PDPN ACVR1 ACVR1 BMP7 BMP7 FERMT2 FERMT2 TGFBR2 TGFBR2 AXIN2 AXIN2 TGFB1I1 TGFB1I1 LEF1 LEF1 IL6 IL6 TGFB3 TGFB3 CTNNB1 CTNNB1 ENG ENG ENSCCAP00000017839 ENSCCAP00000017839 TGFB2 TGFB2 ALX1 ALX1 DAB2 DAB2 EMP2 EMP2 MTOR MTOR BAMBI BAMBI ZNF703 ZNF703 IL1B IL1B SNAI1 SNAI1 ENSCCAP00000023536 ENSCCAP00000023536 MDK MDK TBX20 TBX20 TGFB1 TGFB1 TCF7L2 TCF7L2 LOXL2 LOXL2 RGCC RGCC CRB2 CRB2 WWTR1 WWTR1 TGFBR1 TGFBR1 SMAD4 SMAD4 LOXL3 LOXL3 NOTCH1 NOTCH1 SDCBP SDCBP HDAC2 HDAC2 BCL9L BCL9L SMAD2 SMAD2 TIAM1 TIAM1 GCNT2 GCNT2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMP4Bone morphogenetic protein 4. (408 aa)
ENSCCAP00000000807Uncharacterized protein. (144 aa)
ENSCCAP00000000866Uncharacterized protein. (141 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
OLFM1Olfactomedin 1. (485 aa)
LRG1Leucine rich alpha-2-glycoprotein 1. (348 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (751 aa)
GLIPR2GLI pathogenesis related 2; Belongs to the CRISP family. (154 aa)
ISL1ISL LIM homeobox 1. (349 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
LOC108292702CTNNB1_binding domain-containing protein. (169 aa)
PDPNPodoplanin. (207 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
BMP7Bone morphogenetic protein 7. (430 aa)
FERMT2Fermitin family member 2. (693 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
AXIN2Axin 2. (842 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (461 aa)
LEF1Lymphoid enhancer binding factor 1. (399 aa)
IL6Interleukin 6. (212 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
CTNNB1Catenin beta 1. (781 aa)
ENGEndoglin. (655 aa)
ENSCCAP00000017839Uncharacterized protein. (136 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
ALX1ALX homeobox 1. (326 aa)
DAB2DAB adaptor protein 2. (767 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
MTORSerine/threonine-protein kinase mTOR. (2508 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
ZNF703Zinc finger protein 703. (590 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
ENSCCAP00000023536PTN_MK_N domain-containing protein. (92 aa)
MDKUncharacterized protein. (144 aa)
TBX20T-box transcription factor 20. (447 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (314 aa)
TCF7L2Transcription factor 7 like 2. (430 aa)
LOXL2Lysyl oxidase like 2. (774 aa)
RGCCRegulator of cell cycle. (137 aa)
CRB2Crumbs cell polarity complex component 2. (1291 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (496 aa)
SMAD4Mothers against decapentaplegic homolog. (469 aa)
LOXL3Lysyl oxidase like 3. (753 aa)
NOTCH1Notch receptor 1. (2550 aa)
SDCBPSyndecan binding protein. (317 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
BCL9LBCL9 like. (1497 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1582 aa)
GCNT2Glucosaminyl (N-acetyl) transferase 2 (I blood group). (402 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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