(36 nodes) Regulation of myotube differentiation network (Cebus capucinus)

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	MMP14	Matrix metallopeptidase 14. (592 aa)
	RBM38	RNA binding motif protein 38. (239 aa)
	MYOG	Myogenin. (249 aa)
	NIBAN2	Niban apoptosis regulator 2. (746 aa)
	MYOD1	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
	MYOCD	Myocardin. (987 aa)
	PIEZO1	Piezo-type mechanosensitive ion channel component. (2499 aa)
	PLPP7	Phospholipid phosphatase 7 (inactive). (271 aa)
	NOTCH1	Notch receptor 1. (2550 aa)
	TRIM72	Tripartite motif containing 72. (477 aa)
	HDAC5	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1084 aa)
	CYP26B1	Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
	MYF6	Myogenic factor 6. (242 aa)
	ACTN3	Actinin alpha 3 (gene/pseudogene). (936 aa)
	CCN3	Cellular communication network factor 3. (357 aa)
	MAPK14	Mitogen-activated protein kinase. (360 aa)
	RBM24	RNA binding motif protein 24. (254 aa)
	NKX2-5	NK2 homeobox 5. (324 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (148 aa)
	HDAC4	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1087 aa)
	MAMSTR	MEF2 activating motif and SAP domain containing transcriptional regulator. (415 aa)
	MYF5	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
	XBP1	BZIP domain-containing protein. (375 aa)
	MTOR	Serine/threonine-protein kinase mTOR. (2508 aa)
	MAML1	Mastermind like transcriptional coactivator 1. (1015 aa)
	TBX1	T-box transcription factor 1. (495 aa)
	LMOD3	Leiomodin 3. (561 aa)
	SHOX2	Short stature homeobox 2. (351 aa)
	LOC108285747	Uncharacterized protein. (700 aa)
	FBXO22	F-box protein 22. (476 aa)
	SMYD1	SET and MYND domain containing 1. (490 aa)
	HDAC9	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1069 aa)
	BCL2	BCL2 apoptosis regulator. (240 aa)
	ATP11A	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1191 aa)
	BHLHE41	Basic helix-loop-helix family member e41. (479 aa)
	DMPK	DM1 protein kinase. (630 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTN3	MYF6	ENSCCAP00000028399	ENSCCAP00000029673	Actinin alpha 3 (gene/pseudogene).	Myogenic factor 6.	0.468
BCL2	MAPK14	ENSCCAP00000005426	ENSCCAP00000026755	BCL2 apoptosis regulator.	Mitogen-activated protein kinase.	0.554
BCL2	MTOR	ENSCCAP00000005426	ENSCCAP00000020925	BCL2 apoptosis regulator.	Serine/threonine-protein kinase mTOR.	0.404
BCL2	XBP1	ENSCCAP00000005426	ENSCCAP00000022213	BCL2 apoptosis regulator.	BZIP domain-containing protein.	0.455
CAV3	TRIM72	ENSCCAP00000024638	ENSCCAP00000032450	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Tripartite motif containing 72.	0.812
CCN3	NOTCH1	ENSCCAP00000028297	ENSCCAP00000033380	Cellular communication network factor 3.	Notch receptor 1.	0.418
HDAC4	HDAC5	ENSCCAP00000024416	ENSCCAP00000031480	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.921
HDAC4	HDAC9	ENSCCAP00000024416	ENSCCAP00000006350	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.714
HDAC4	MYOD1	ENSCCAP00000024416	ENSCCAP00000037095	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.474
HDAC5	HDAC4	ENSCCAP00000031480	ENSCCAP00000024416	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.921
HDAC9	HDAC4	ENSCCAP00000006350	ENSCCAP00000024416	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.714
MAML1	NOTCH1	ENSCCAP00000020567	ENSCCAP00000033380	Mastermind like transcriptional coactivator 1.	Notch receptor 1.	0.996
MAPK14	BCL2	ENSCCAP00000026755	ENSCCAP00000005426	Mitogen-activated protein kinase.	BCL2 apoptosis regulator.	0.554
MAPK14	MTOR	ENSCCAP00000026755	ENSCCAP00000020925	Mitogen-activated protein kinase.	Serine/threonine-protein kinase mTOR.	0.420
MAPK14	MYF6	ENSCCAP00000026755	ENSCCAP00000029673	Mitogen-activated protein kinase.	Myogenic factor 6.	0.467
MAPK14	MYOD1	ENSCCAP00000026755	ENSCCAP00000037095	Mitogen-activated protein kinase.	Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation.	0.621
MAPK14	MYOG	ENSCCAP00000026755	ENSCCAP00000037926	Mitogen-activated protein kinase.	Myogenin.	0.530
MMP14	MYOG	ENSCCAP00000011713	ENSCCAP00000037926	Matrix metallopeptidase 14.	Myogenin.	0.448
MTOR	BCL2	ENSCCAP00000020925	ENSCCAP00000005426	Serine/threonine-protein kinase mTOR.	BCL2 apoptosis regulator.	0.404
MTOR	MAPK14	ENSCCAP00000020925	ENSCCAP00000026755	Serine/threonine-protein kinase mTOR.	Mitogen-activated protein kinase.	0.420