STRINGSTRING
GRN GRN TREM2 TREM2 C1QA C1QA GFAP GFAP DLL1 DLL1 CNTF CNTF IFNG IFNG NF1 NF1 ROR2 ROR2 IFNGR1 IFNGR1 EIF2B5 EIF2B5 S100A9 S100A9 MT3 MT3 APP APP ADORA2A ADORA2A S100A8 S100A8 VIM VIM LAMC3 LAMC3 CDK6 CDK6 AGER AGER SMO SMO C5AR1 C5AR1 LAMB2 LAMB2 TSPAN2 TSPAN2 ROR1 ROR1 PSEN1 PSEN1 LRP1 LRP1 PLP1 PLP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GRNGranulin precursor. (595 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (230 aa)
C1QAComplement C1q A chain. (245 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (506 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
CNTFCiliary neurotrophic factor. (200 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (166 aa)
NF1Neurofibromin 1. (2839 aa)
ROR2Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (943 aa)
IFNGR1Interferon gamma receptor 1. (484 aa)
EIF2B5Eukaryotic translation initiation factor 2B subunit epsilon. (728 aa)
S100A9S100 calcium binding protein A9; Belongs to the S-100 family. (110 aa)
MT3Metallothionein 3; Belongs to the metallothionein superfamily. Type 1 family. (113 aa)
APPAmyloid beta precursor protein. (770 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (413 aa)
S100A8Protein S100; Belongs to the S-100 family. (89 aa)
VIMVimentin; Belongs to the intermediate filament family. (466 aa)
LAMC3Laminin subunit gamma 3. (1527 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
AGERAdvanced glycosylation end-product specific receptor. (403 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (789 aa)
C5AR1Complement C5a receptor 1; Belongs to the G-protein coupled receptor 1 family. (347 aa)
LAMB2Laminin subunit beta 2. (1798 aa)
TSPAN2Tetraspanin. (221 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa)
PSEN1Presenilin 1. (419 aa)
LRP1LDL receptor related protein 1. (4544 aa)
PLP1Proteolipid protein 1. (277 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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