(56 nodes) Cholesterol binding network (Cebus capucinus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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gene fusions

gene co-occurrence

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protein homology

Your Input:
	STAR	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa)
	PTCH1	Patched 1. (1452 aa)
	STARD3NL	STARD3 N-terminal like. (234 aa)
	ENSCCAP00000008456	Uncharacterized protein. (274 aa)
	ENSCCAP00000009265	Uncharacterized protein. (287 aa)
	ABCG1	ATP binding cassette subfamily G member 1. (666 aa)
	OSBPL5	Oxysterol-binding protein; Belongs to the OSBP family. (879 aa)
	NPC2	ML domain-containing protein. (178 aa)
	CD81	Tetraspanin. (236 aa)
	SCP2	Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (500 aa)
	LOC108299117	Uncharacterized protein. (282 aa)
	STARD5	StAR related lipid transfer domain containing 5. (213 aa)
	TSPO2	Translocator protein 2. (170 aa)
	ENSCCAP00000012654	Uncharacterized protein. (277 aa)
	SIDT1	SID1 transmembrane family member 1. (827 aa)
	APOA1	Apolipoprotein A1. (267 aa)
	OSBPL6	Oxysterol-binding protein; Belongs to the OSBP family. (967 aa)
	SYP	Synaptophysin. (313 aa)
	OSBPL7	Oxysterol-binding protein; Belongs to the OSBP family. (848 aa)
	SYNPR	Synaptoporin. (277 aa)
	APOA5	Apolipoprotein A5. (366 aa)
	OSBPL1A	Oxysterol-binding protein; Belongs to the OSBP family. (1032 aa)
	CETP	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (493 aa)
	GRAMD1C	GRAM domain containing 1C. (637 aa)
	SULT2B1	Sulfotransferase; Belongs to the sulfotransferase 1 family. (341 aa)
	SOAT1	O-acyltransferase. (506 aa)
	STARD4	StAR related lipid transfer domain containing 4. (206 aa)
	NFE2L1	Nuclear factor, erythroid 2 like 1. (770 aa)
	VDAC1	Voltage dependent anion channel 1. (292 aa)
	OSBPL10	Oxysterol-binding protein; Belongs to the OSBP family. (764 aa)
	ENSCCAP00000019230	Oxysterol-binding protein; Belongs to the OSBP family. (853 aa)
	PMP2	Peripheral myelin protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (132 aa)
	OSBP2	Oxysterol-binding protein; Belongs to the OSBP family. (916 aa)
	OSBPL2	Oxysterol-binding protein; Belongs to the OSBP family. (480 aa)
	STARD3	StAR related lipid transfer domain containing 3. (476 aa)
	APOF	Apolipoprotein F. (326 aa)
	NPC1	NPC intracellular cholesterol transporter 1. (1294 aa)
	ENSCCAP00000036608	Uncharacterized protein. (267 aa)
	GRAMD1B	GRAM domain containing 1B. (877 aa)
	ERLIN1	ER lipid raft associated 1. (345 aa)
	APOA2	Apolipoprotein A2. (133 aa)
	GRAMD1A	GRAM domain containing 1A. (807 aa)
	OSBPL3	Oxysterol-binding protein; Belongs to the OSBP family. (887 aa)
	LOC108307977	ML domain-containing protein. (151 aa)
	ANXA6	Annexin. (673 aa)
	ABCA1	ATP binding cassette subfamily A member 1. (2258 aa)
	APOD	Apolipoprotein D. (189 aa)
	OSBPL8	PH domain-containing protein. (846 aa)
	TSPO	Translocator protein. (169 aa)
	PROM2	Prominin 2. (836 aa)
	SCARB2	Scavenger receptor class B member 2; Belongs to the CD36 family. (478 aa)
	NR1H3	Nuclear receptor subfamily 1 group H member 3. (447 aa)
	SOAT2	O-acyltransferase. (526 aa)
	VDAC2	Uncharacterized protein. (301 aa)
	NPC1L1	NPC1 like intracellular cholesterol transporter 1. (1330 aa)
	PROM1	Prominin 1. (865 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA1	ABCG1	ENSCCAP00000040411	ENSCCAP00000009633	ATP binding cassette subfamily A member 1.	ATP binding cassette subfamily G member 1.	0.437
ABCA1	APOA1	ENSCCAP00000040411	ENSCCAP00000013613	ATP binding cassette subfamily A member 1.	Apolipoprotein A1.	0.774
ABCA1	APOA2	ENSCCAP00000040411	ENSCCAP00000037354	ATP binding cassette subfamily A member 1.	Apolipoprotein A2.	0.524
ABCA1	APOD	ENSCCAP00000040411	ENSCCAP00000018307	ATP binding cassette subfamily A member 1.	Apolipoprotein D.	0.428
ABCA1	CETP	ENSCCAP00000040411	ENSCCAP00000027699	ATP binding cassette subfamily A member 1.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.751
ABCA1	NPC1	ENSCCAP00000040411	ENSCCAP00000035653	ATP binding cassette subfamily A member 1.	NPC intracellular cholesterol transporter 1.	0.643
ABCA1	NPC1L1	ENSCCAP00000040411	ENSCCAP00000003291	ATP binding cassette subfamily A member 1.	NPC1 like intracellular cholesterol transporter 1.	0.664
ABCA1	NR1H3	ENSCCAP00000040411	ENSCCAP00000014114	ATP binding cassette subfamily A member 1.	Nuclear receptor subfamily 1 group H member 3.	0.785
ABCA1	SCARB2	ENSCCAP00000040411	ENSCCAP00000015816	ATP binding cassette subfamily A member 1.	Scavenger receptor class B member 2; Belongs to the CD36 family.	0.442
ABCG1	ABCA1	ENSCCAP00000009633	ENSCCAP00000040411	ATP binding cassette subfamily G member 1.	ATP binding cassette subfamily A member 1.	0.437
ABCG1	CETP	ENSCCAP00000009633	ENSCCAP00000027699	ATP binding cassette subfamily G member 1.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.653
ABCG1	NPC1	ENSCCAP00000009633	ENSCCAP00000035653	ATP binding cassette subfamily G member 1.	NPC intracellular cholesterol transporter 1.	0.665
ABCG1	NPC1L1	ENSCCAP00000009633	ENSCCAP00000003291	ATP binding cassette subfamily G member 1.	NPC1 like intracellular cholesterol transporter 1.	0.416
ABCG1	NR1H3	ENSCCAP00000009633	ENSCCAP00000014114	ATP binding cassette subfamily G member 1.	Nuclear receptor subfamily 1 group H member 3.	0.572
ABCG1	SCARB2	ENSCCAP00000009633	ENSCCAP00000015816	ATP binding cassette subfamily G member 1.	Scavenger receptor class B member 2; Belongs to the CD36 family.	0.437
APOA1	ABCA1	ENSCCAP00000013613	ENSCCAP00000040411	Apolipoprotein A1.	ATP binding cassette subfamily A member 1.	0.774
APOA1	APOA2	ENSCCAP00000013613	ENSCCAP00000037354	Apolipoprotein A1.	Apolipoprotein A2.	0.836
APOA1	APOA5	ENSCCAP00000013613	ENSCCAP00000029981	Apolipoprotein A1.	Apolipoprotein A5.	0.660
APOA1	CETP	ENSCCAP00000013613	ENSCCAP00000027699	Apolipoprotein A1.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.691
APOA1	SCARB2	ENSCCAP00000013613	ENSCCAP00000015816	Apolipoprotein A1.	Scavenger receptor class B member 2; Belongs to the CD36 family.	0.414