(17 nodes) Dopamine transport network (Cebus capucinus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SLC6A2	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (627 aa)
	LOC108305208	DJ-1_PfpI domain-containing protein. (149 aa)
	ENSCCAP00000038186	DJ-1_PfpI domain-containing protein. (132 aa)
	SLC22A3	Solute carrier family 22 member 3. (555 aa)
	SLC18A2	Solute carrier family 18 member A2. (517 aa)
	SLC22A1	Solute carrier family 22 member 1. (552 aa)
	PINK1	PTEN induced kinase 1. (581 aa)
	ENSCCAP00000013848	DJ-1_PfpI domain-containing protein. (153 aa)
	PRKN	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
	SLC29A4	Solute carrier family 29 member 4. (530 aa)
	SLC6A3	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (687 aa)
	ENSCCAP00000009736	DJ-1_PfpI domain-containing protein. (174 aa)
	MAPK15	Mitogen-activated protein kinase. (547 aa)
	PARK7	DJ-1_PfpI domain-containing protein. (189 aa)
	SLC22A2	Solute carrier family 22 member 2. (519 aa)
	DRD2	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
	ENSCCAP00000000830	DJ-1_PfpI domain-containing protein. (140 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DRD2	SLC18A2	ENSCCAP00000004749	ENSCCAP00000032461	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	Solute carrier family 18 member A2.	0.504
DRD2	SLC6A2	ENSCCAP00000004749	ENSCCAP00000040427	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.525
DRD2	SLC6A3	ENSCCAP00000004749	ENSCCAP00000012224	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.905
ENSCCAP00000000830	PINK1	ENSCCAP00000000830	ENSCCAP00000023571	DJ-1_PfpI domain-containing protein.	PTEN induced kinase 1.	0.424
ENSCCAP00000000830	PRKN	ENSCCAP00000000830	ENSCCAP00000013471	DJ-1_PfpI domain-containing protein.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.801
ENSCCAP00000009736	PINK1	ENSCCAP00000009736	ENSCCAP00000023571	DJ-1_PfpI domain-containing protein.	PTEN induced kinase 1.	0.424
ENSCCAP00000009736	PRKN	ENSCCAP00000009736	ENSCCAP00000013471	DJ-1_PfpI domain-containing protein.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.801
ENSCCAP00000013848	PINK1	ENSCCAP00000013848	ENSCCAP00000023571	DJ-1_PfpI domain-containing protein.	PTEN induced kinase 1.	0.424
ENSCCAP00000013848	PRKN	ENSCCAP00000013848	ENSCCAP00000013471	DJ-1_PfpI domain-containing protein.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.801
ENSCCAP00000038186	PINK1	ENSCCAP00000038186	ENSCCAP00000023571	DJ-1_PfpI domain-containing protein.	PTEN induced kinase 1.	0.424
ENSCCAP00000038186	PRKN	ENSCCAP00000038186	ENSCCAP00000013471	DJ-1_PfpI domain-containing protein.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.801
LOC108305208	PINK1	ENSCCAP00000038196	ENSCCAP00000023571	DJ-1_PfpI domain-containing protein.	PTEN induced kinase 1.	0.424
LOC108305208	PRKN	ENSCCAP00000038196	ENSCCAP00000013471	DJ-1_PfpI domain-containing protein.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.801
PARK7	PINK1	ENSCCAP00000008902	ENSCCAP00000023571	DJ-1_PfpI domain-containing protein.	PTEN induced kinase 1.	0.424
PARK7	PRKN	ENSCCAP00000008902	ENSCCAP00000013471	DJ-1_PfpI domain-containing protein.	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.	0.801
PINK1	ENSCCAP00000000830	ENSCCAP00000023571	ENSCCAP00000000830	PTEN induced kinase 1.	DJ-1_PfpI domain-containing protein.	0.424
PINK1	ENSCCAP00000009736	ENSCCAP00000023571	ENSCCAP00000009736	PTEN induced kinase 1.	DJ-1_PfpI domain-containing protein.	0.424
PINK1	ENSCCAP00000013848	ENSCCAP00000023571	ENSCCAP00000013848	PTEN induced kinase 1.	DJ-1_PfpI domain-containing protein.	0.424
PINK1	ENSCCAP00000038186	ENSCCAP00000023571	ENSCCAP00000038186	PTEN induced kinase 1.	DJ-1_PfpI domain-containing protein.	0.424
PINK1	LOC108305208	ENSCCAP00000023571	ENSCCAP00000038196	PTEN induced kinase 1.	DJ-1_PfpI domain-containing protein.	0.424