STRINGSTRING
RUFY4 RUFY4 ENSCCAP00000000077 ENSCCAP00000000077 TEX264 TEX264 AUP1 AUP1 UVRAG UVRAG LOC108284318 LOC108284318 ARL8A ARL8A ATG16L1 ATG16L1 STBD1 STBD1 STX17 STX17 STING1 STING1 UBQLN2 UBQLN2 UBA5 UBA5 MAP1LC3C MAP1LC3C PGAM5 PGAM5 ILRUN ILRUN PIK3R4 PIK3R4 CHMP2B CHMP2B EMC6 EMC6 RAB33B RAB33B VPS37A VPS37A ATG9A ATG9A EPG5 EPG5 WIPI2 WIPI2 PIK3C3 PIK3C3 RAB23 RAB23 ATG101 ATG101 ENSCCAP00000005562 ENSCCAP00000005562 VPS41 VPS41 GABARAPL2 GABARAPL2 PLAA PLAA ATG3 ATG3 DDRGK1 DDRGK1 ULK3 ULK3 ENSCCAP00000007309 ENSCCAP00000007309 SMURF1 SMURF1 BAG3 BAG3 RETREG1 RETREG1 ULK2 ULK2 PACS2 PACS2 ZFYVE26 ZFYVE26 NBR1 NBR1 RETREG3 RETREG3 PSEN1 PSEN1 AMBRA1 AMBRA1 VPS4A VPS4A VPS39 VPS39 PJVK PJVK MAPK3 MAPK3 ATG16L2 ATG16L2 CLN3 CLN3 RAB7A RAB7A VPS28 VPS28 TSG101 TSG101 SRC SRC TECPR1 TECPR1 ATG12 ATG12 ENSCCAP00000008966 ENSCCAP00000008966 ATG5 ATG5 RB1CC1 RB1CC1 PHB2 PHB2 ARFIP2 ARFIP2 SPATA33 SPATA33 ENSCCAP00000009704 ENSCCAP00000009704 RETREG2 RETREG2 HMOX1 HMOX1 TIGAR TIGAR MAP1LC3B MAP1LC3B LOC108282418 LOC108282418 STX12 STX12 VPS25 VPS25 MVB12A MVB12A LOC108305632 LOC108305632 RUBCNL RUBCNL ENSCCAP00000011796 ENSCCAP00000011796 RAB43 RAB43 LAMP2 LAMP2 NOD1 NOD1 PRKN PRKN SNAPIN SNAPIN VMP1 VMP1 CHMP4C CHMP4C LGALS8 LGALS8 UFM1 UFM1 ULK1 ULK1 PIK3C2B PIK3C2B USP30 USP30 SNF8 SNF8 NSFL1C NSFL1C UBXN2A UBXN2A TP53INP1 TP53INP1 LOC108310106 LOC108310106 AP4M1 AP4M1 VPS36 VPS36 ATG2B ATG2B YOD1 YOD1 EPM2A EPM2A WDR45 WDR45 MFN2 MFN2 MAP1LC3A MAP1LC3A OGT OGT ENSCCAP00000018340 ENSCCAP00000018340 CHMP5 CHMP5 LOC108310005 LOC108310005 VAMP8 VAMP8 CHMP7 CHMP7 ENSCCAP00000020515 ENSCCAP00000020515 MTOR MTOR VPS16 VPS16 PIP4K2A PIP4K2A ARL8B ARL8B ATG14 ATG14 ATG4D ATG4D ENSCCAP00000022103 ENSCCAP00000022103 MTMR14 MTMR14 STAM STAM TP53INP2 TP53INP2 VTI1A VTI1A WIPI1 WIPI1 C5orf51 C5orf51 RAB19 RAB19 TMEM41B TMEM41B ATG4B ATG4B ENSCCAP00000023295 ENSCCAP00000023295 PINK1 PINK1 ATP13A2 ATP13A2 KIAA1324 KIAA1324 UBXN6 UBXN6 UBXN2B UBXN2B ATG9B ATG9B TCIRG1 TCIRG1 EI24 EI24 VPS33A VPS33A VCP VCP MCOLN1 MCOLN1 RIPK2 RIPK2 STAM2 STAM2 PLEKHM1 PLEKHM1 CHMP6 CHMP6 LOC108283915 LOC108283915 PIP4K2B PIP4K2B HGS HGS MFSD8 MFSD8 ENSCCAP00000028878 ENSCCAP00000028878 TP53 TP53 UFL1 UFL1 TAZ TAZ ATG13 ATG13 ENSCCAP00000031066 ENSCCAP00000031066 SNX14 SNX14 LRBA LRBA CALCOCO2 CALCOCO2 SNX30 SNX30 MTMR3 MTMR3 WDR45B WDR45B SQSTM1 SQSTM1 TRAPPC8 TRAPPC8 ATP2A2 ATP2A2 ENSCCAP00000032765 ENSCCAP00000032765 SNAP29 SNAP29 ATG2A ATG2A NOD2 NOD2 SYNPO2 SYNPO2 LOC108295942 LOC108295942 CHMP2A CHMP2A UFC1 UFC1 ATG7 ATG7 BECN1 BECN1 CHMP4B CHMP4B LOC108289809 LOC108289809 CHMP1A CHMP1A VPS37B VPS37B TBC1D5 TBC1D5 NPC1 NPC1 SPG11 SPG11 WDFY3 WDFY3 ATG10 ATG10 LIX1 LIX1 WDR81 WDR81 RAB1A RAB1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RUFY4RUN and FYVE domain containing 4. (501 aa)
ENSCCAP00000000077Uncharacterized protein. (56 aa)
TEX264Testis expressed 264, ER-phagy receptor. (313 aa)
AUP1AUP1 lipid droplet regulating VLDL assembly factor. (410 aa)
UVRAGUV radiation resistance associated. (699 aa)
LOC108284318Uncharacterized protein. (194 aa)
ARL8AADP ribosylation factor like GTPase 8A; Belongs to the small GTPase superfamily. Arf family. (186 aa)
ATG16L1Autophagy related 16 like 1. (624 aa)
STBD1Starch binding domain 1. (355 aa)
STX17Syntaxin 17; Belongs to the syntaxin family. (302 aa)
STING1Transmembrane protein 173. (379 aa)
UBQLN2Ubiquilin 2. (624 aa)
UBA5Ubiquitin like modifier activating enzyme 5. (404 aa)
MAP1LC3CMicrotubule associated protein 1 light chain 3 gamma. (147 aa)
PGAM5PGAM family member 5, mitochondrial serine/threonine protein phosphatase. (289 aa)
ILRUNInflammation and lipid regulator with UBA-like and NBR1-like domains. (291 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa)
CHMP2BCharged multivesicular body protein 2B. (215 aa)
EMC6ER membrane protein complex subunit 6. (110 aa)
RAB33BRAB33B, member RAS oncogene family. (229 aa)
VPS37AVPS37A subunit of ESCRT-I. (397 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (839 aa)
EPG5Ectopic P-granules autophagy protein 5 homolog. (2578 aa)
WIPI2WD repeat domain, phosphoinositide interacting 2. (456 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
RAB23RAB23, member RAS oncogene family. (237 aa)
ATG101Autophagy related 101. (218 aa)
ENSCCAP00000005562SKICH domain-containing protein. (394 aa)
VPS41VPS41 subunit of HOPS complex. (685 aa)
GABARAPL2GABA type A receptor associated protein like 2. (117 aa)
PLAAPhospholipase A2 activating protein. (803 aa)
ATG3Autophagy-related protein 3. (307 aa)
DDRGK1DDRGK domain containing 1. (315 aa)
ULK3Unc-51 like kinase 3. (480 aa)
ENSCCAP00000007309Uncharacterized protein. (70 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
BAG3BCL2 associated athanogene 3. (576 aa)
RETREG1Reticulophagy regulator 1. (494 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1022 aa)
PACS2Phosphofurin acidic cluster sorting protein 2. (904 aa)
ZFYVE26Zinc finger FYVE-type containing 26. (2542 aa)
NBR1NBR1 autophagy cargo receptor. (960 aa)
RETREG3Reticulophagy regulator family member 3. (466 aa)
PSEN1Presenilin 1. (419 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1298 aa)
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
VPS39VPS39 subunit of HOPS complex. (886 aa)
PJVKPejvakin. (352 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
ATG16L2Autophagy related 16 like 2. (619 aa)
CLN3Battenin. (491 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
VPS28Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (255 aa)
TSG101Tumor susceptibility 101. (395 aa)
SRCTyrosine-protein kinase. (542 aa)
TECPR1Tectonin beta-propeller repeat containing 1. (1165 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
ENSCCAP00000008966Uncharacterized protein. (183 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
RB1CC1RB1 inducible coiled-coil 1. (1594 aa)
PHB2Prohibitin. (299 aa)
ARFIP2ADP ribosylation factor interacting protein 2. (373 aa)
SPATA33Spermatogenesis associated 33. (145 aa)
ENSCCAP00000009704Glyco_transf_41 domain-containing protein. (100 aa)
RETREG2Reticulophagy regulator family member 2. (543 aa)
HMOX1Heme oxygenase 1. (297 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
MAP1LC3BUncharacterized protein. (102 aa)
LOC108282418Prohibitin. (291 aa)
STX12Syntaxin 12; Belongs to the syntaxin family. (330 aa)
VPS25Vacuolar protein sorting 25 homolog. (176 aa)
MVB12AMultivesicular body subunit 12A. (273 aa)
LOC108305632V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (174 aa)
RUBCNLRubicon like autophagy enhancer. (663 aa)
ENSCCAP00000011796VPS37 C-terminal domain-containing protein. (358 aa)
RAB43RAB43, member RAS oncogene family. (212 aa)
LAMP2Lysosomal associated membrane protein 2. (411 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
VMP1Vacuole membrane protein 1. (421 aa)
CHMP4CCharged multivesicular body protein 4C. (233 aa)
LGALS8Galectin. (359 aa)
UFM1Ubiquitin fold modifier 1. (115 aa)
ULK1Unc-51 like autophagy activating kinase 1. (964 aa)
PIK3C2BPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1634 aa)
USP30Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (534 aa)
SNF8SNF8 subunit of ESCRT-II. (299 aa)
NSFL1CNSFL1 cofactor. (372 aa)
UBXN2AUBX domain protein 2A. (254 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (241 aa)
LOC108310106Autophagy-related protein 3. (302 aa)
AP4M1AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] (453 aa)
VPS36Vacuolar protein sorting 36 homolog. (363 aa)
ATG2BAutophagy related 2B. (2079 aa)
YOD1YOD1 deubiquitinase. (348 aa)
EPM2AEPM2A glucan phosphatase, laforin. (331 aa)
WDR45Uncharacterized protein. (361 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
MAP1LC3AMicrotubule associated protein 1 light chain 3 alpha. (122 aa)
OGTTPR_REGION domain-containing protein. (1046 aa)
ENSCCAP00000018340Uncharacterized protein. (166 aa)
CHMP5Uncharacterized protein. (219 aa)
LOC108310005Uncharacterized protein. (221 aa)
VAMP8Vesicle associated membrane protein 8. (100 aa)
CHMP7Charged multivesicular body protein 7. (453 aa)
ENSCCAP00000020515Uncharacterized protein. (52 aa)
MTORSerine/threonine-protein kinase mTOR. (2508 aa)
VPS16Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (848 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (406 aa)
ARL8BADP ribosylation factor like GTPase 8B; Belongs to the small GTPase superfamily. Arf family. (186 aa)
ATG14Autophagy related 14. (510 aa)
ATG4DCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (496 aa)
ENSCCAP00000022103Uncharacterized protein. (239 aa)
MTMR14Myotubularin related protein 14. (650 aa)
STAMSignal transducing adaptor molecule. (540 aa)
TP53INP2Tumor protein p53 inducible nuclear protein 2. (220 aa)
VTI1AVesicle transport through interaction with t-SNAREs 1A. (217 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (446 aa)
C5orf51Chromosome 5 open reading frame 51. (293 aa)
RAB19RAB19, member RAS oncogene family. (217 aa)
TMEM41BTransmembrane protein 41B. (291 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (394 aa)
ENSCCAP00000023295Uncharacterized protein. (146 aa)
PINK1PTEN induced kinase 1. (581 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1204 aa)
KIAA1324KIAA1324. (927 aa)
UBXN6UBX domain protein 6. (441 aa)
UBXN2BUBX domain protein 2B. (331 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (921 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (829 aa)
EI24EI24 autophagy associated transmembrane protein. (300 aa)
VPS33AUncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (577 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (807 aa)
MCOLN1Mucolipin 1. (468 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (540 aa)
STAM2Signal transducing adaptor molecule 2. (534 aa)
PLEKHM1RUN domain-containing protein. (335 aa)
CHMP6Charged multivesicular body protein 6. (201 aa)
LOC108283915Prohibitin. (285 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (416 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (802 aa)
MFSD8Major facilitator superfamily domain containing 8. (560 aa)
ENSCCAP00000028878Uncharacterized protein. (111 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (395 aa)
UFL1UFM1 specific ligase 1. (792 aa)
TAZTafazzin family protein; Some isoforms may be involved in cardiolipin metabolism. (247 aa)
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (527 aa)
ENSCCAP00000031066Uncharacterized protein. (379 aa)
SNX14Sorting nexin 14. (918 aa)
LRBALPS responsive beige-like anchor protein. (2841 aa)
CALCOCO2Uncharacterized protein. (470 aa)
SNX30Sorting nexin family member 30. (445 aa)
MTMR3Myotubularin related protein 3. (1220 aa)
WDR45BWD repeat domain 45B. (344 aa)
SQSTM1Sequestosome 1. (439 aa)
TRAPPC8Trafficking protein particle complex 8. (1435 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
ENSCCAP00000032765Uncharacterized protein. (271 aa)
SNAP29Synaptosome associated protein 29. (258 aa)
ATG2AAutophagy related 2A. (1941 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1040 aa)
SYNPO2Synaptopodin 2. (1245 aa)
LOC108295942Autophagy-related protein 3. (310 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
UFC1Ubiquitin-fold modifier-conjugating enzyme 1; E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage. (166 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (707 aa)
BECN1Beclin 1. (450 aa)
CHMP4BCharged multivesicular body protein 4B. (224 aa)
LOC108289809Uncharacterized protein. (87 aa)
CHMP1ACharged multivesicular body protein 1A. (331 aa)
VPS37BVPS37B subunit of ESCRT-I. (285 aa)
TBC1D5TBC1 domain family member 5. (839 aa)
NPC1NPC intracellular cholesterol transporter 1. (1294 aa)
SPG11SPG11 vesicle trafficking associated, spatacsin. (2387 aa)
WDFY3WD repeat and FYVE domain containing 3. (3526 aa)
ATG10Autophagy related 10. (220 aa)
LIX1Limb and CNS expressed 1. (282 aa)
WDR81WD repeat domain 81. (1937 aa)
RAB1ARAB1A, member RAS oncogene family. (205 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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