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POLI POLI ENSCCAP00000017159 ENSCCAP00000017159 POLN POLN CMAS CMAS POLR3H POLR3H TAMM41 TAMM41 POLR2B POLR2B POLG2 POLG2 POLR2E POLR2E TENT2 TENT2 PRIMPOL PRIMPOL NANS NANS PAPOLA PAPOLA TUT7 TUT7 POLRMT POLRMT THG1L THG1L ENSCCAP00000014053 ENSCCAP00000014053 CGAS CGAS ABL1 ABL1 TENT5A TENT5A OAS2 OAS2 NDUFA4L2 NDUFA4L2 POLA1 POLA1 POLE4 POLE4 GMPPA GMPPA RPAP1 RPAP1 POLR2I POLR2I UAP1L1 UAP1L1 NMNAT1 NMNAT1 POLR3F POLR3F FLAD1 FLAD1 POLL POLL ENSCCAP00000007567 ENSCCAP00000007567 LOC108310472 LOC108310472 LOC108306844 LOC108306844 PCYT1B PCYT1B POLR2A POLR2A GPHN GPHN TENT5C TENT5C ENSCCAP00000005315 ENSCCAP00000005315 ENSCCAP00000005186 ENSCCAP00000005186 MAB21L1 MAB21L1 ENSCCAP00000005058 ENSCCAP00000005058 POLR1C POLR1C ENSCCAP00000004993 ENSCCAP00000004993 POLR1A POLR1A POLD4 POLD4 POLR2K POLR2K MAB21L2 MAB21L2 ENSCCAP00000000379 ENSCCAP00000000379 TRNT1 TRNT1 LOC108318591 LOC108318591 EIF2B3 EIF2B3 POLG POLG TENT4A TENT4A GMPPB GMPPB ENSCCAP00000001945 ENSCCAP00000001945 PAPSS2 PAPSS2 PRIM1 PRIM1 OAS1 OAS1 TUT1 TUT1 OAS3 OAS3 FICD FICD POLR2J POLR2J ENSCCAP00000024462 ENSCCAP00000024462 CLMP CLMP NUDT5 NUDT5 ENSCCAP00000025267 ENSCCAP00000025267 RNGTT RNGTT CTU2 CTU2 TERT TERT MTPAP MTPAP POLD1 POLD1 POLE POLE COASY COASY LOC108307710 LOC108307710 POLR3G POLR3G MOCS3 MOCS3 MED21 MED21 CHRAC1 CHRAC1 POLR3A POLR3A CRPPA CRPPA KARS1 KARS1 PCYT2 PCYT2 POLM POLM FHIT FHIT POLB POLB POLR1B POLR1B TENT4B TENT4B TEP1 TEP1 POLR2L POLR2L POLR2C POLR2C POLE2 POLE2 POLR3K POLR3K POLR2F POLR2F TENT5B TENT5B CDS1 CDS1 SELENOO SELENOO NMNAT3 NMNAT3 TUT4 TUT4 TWISTNB TWISTNB DNTT DNTT HAUS3 HAUS3 ARID3A ARID3A ENSCCAP00000039839 ENSCCAP00000039839 CTU1 CTU1 POLH POLH PNPT1 PNPT1 UGP2 UGP2 FPGT FPGT REV3L REV3L UAP1 UAP1 POLR3B POLR3B POLK POLK YRDC YRDC NMNAT2 NMNAT2 PAPSS1 PAPSS1 OASL OASL PCYT1A PCYT1A DKC1 DKC1 MB21D2 MB21D2 REV1 REV1 POLR3C POLR3C PAPOLG PAPOLG CDS2 CDS2 POLQ POLQ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POLIDNA polymerase iota. (738 aa)
ENSCCAP00000017159Uncharacterized protein. (58 aa)
POLNDNA polymerase nu. (879 aa)
CMASCytidine monophosphate N-acetylneuraminic acid synthetase. (434 aa)
POLR3HRNA polymerase III subunit H. (224 aa)
TAMM41Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane. (445 aa)
POLR2BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1174 aa)
POLG2DNA polymerase gamma 2, accessory subunit. (485 aa)
POLR2ERNA polymerase II subunit E. (227 aa)
TENT2Terminal nucleotidyltransferase 2. (484 aa)
PRIMPOLUncharacterized protein. (454 aa)
NANSN-acetylneuraminate synthase. (359 aa)
PAPOLAPoly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (745 aa)
TUT7Uncharacterized protein. (1493 aa)
POLRMTDNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1264 aa)
THG1LtRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. (298 aa)
ENSCCAP00000014053DNA_pol_B domain-containing protein. (262 aa)
CGASCyclic GMP-AMP synthase. (521 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
TENT5ATerminal nucleotidyltransferase 5A. (506 aa)
OAS22'-5'-oligoadenylate synthetase 2. (726 aa)
NDUFA4L2NDUFA4 mitochondrial complex associated like 2. (87 aa)
POLA1DNA polymerase. (1391 aa)
POLE4DNA polymerase epsilon 4, accessory subunit. (119 aa)
GMPPAGDP-mannose pyrophosphorylase A. (420 aa)
RPAP1RNA polymerase II associated protein 1. (1392 aa)
POLR2IDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
UAP1L1UDP-N-acetylglucosamine pyrophosphorylase 1 like 1. (507 aa)
NMNAT1Nicotinamide-nucleotide adenylyltransferase. (280 aa)
POLR3FDNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (280 aa)
FLAD1FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. (562 aa)
POLLDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (644 aa)
ENSCCAP00000007567Uncharacterized protein. (253 aa)
LOC108310472RNA_pol_L_2 domain-containing protein. (133 aa)
LOC108306844Uncharacterized protein. (540 aa)
PCYT1BPhosphate cytidylyltransferase 1, choline, beta. (369 aa)
POLR2ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1970 aa)
GPHNMolybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (752 aa)
TENT5CTerminal nucleotidyltransferase 5C. (391 aa)
ENSCCAP00000005315UmuC domain-containing protein. (176 aa)
ENSCCAP00000005186Uncharacterized protein. (110 aa)
MAB21L1Mab-21 like 1. (359 aa)
ENSCCAP00000005058RNA_pol_L_2 domain-containing protein. (119 aa)
POLR1CRNA polymerase I and III subunit C. (367 aa)
ENSCCAP00000004993Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. (193 aa)
POLR1ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1720 aa)
POLD4Uncharacterized protein. (107 aa)
POLR2KRNA polymerase II subunit K. (58 aa)
MAB21L2Mab-21 like 2. (359 aa)
ENSCCAP00000000379Uncharacterized protein. (57 aa)
TRNT1tRNA nucleotidyl transferase 1; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (416 aa)
LOC108318591Uncharacterized protein. (58 aa)
EIF2B3Eukaryotic translation initiation factor 2B subunit gamma. (403 aa)
POLGDNA polymerase gamma, catalytic subunit. (1230 aa)
TENT4ATerminal nucleotidyltransferase 4A. (793 aa)
GMPPBGDP-mannose pyrophosphorylase B. (360 aa)
ENSCCAP00000001945Uncharacterized protein. (71 aa)
PAPSS23'-phosphoadenosine 5'-phosphosulfate synthase 2. (614 aa)
PRIM1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (353 aa)
OAS12'-5'-oligoadenylate synthetase 1. (400 aa)
TUT1RRM domain-containing protein. (912 aa)
OAS32'-5'-oligoadenylate synthetase 3. (995 aa)
FICDFIC domain containing. (458 aa)
POLR2JRNA_pol_L_2 domain-containing protein. (185 aa)
ENSCCAP00000024462CTP_transf_like domain-containing protein. (163 aa)
CLMPCXADR like membrane protein. (376 aa)
NUDT5Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. (230 aa)
ENSCCAP00000025267AA_TRNA_LIGASE_II domain-containing protein. (548 aa)
RNGTTPolynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (597 aa)
CTU2Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Belongs to the CTU2/NCS2 family. (557 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1121 aa)
MTPAPMitochondrial poly(A) polymerase. (582 aa)
POLD1DNA polymerase. (1105 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2286 aa)
COASYCoenzyme A synthase. (580 aa)
LOC108307710DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (125 aa)
POLR3GDNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (223 aa)
MOCS3Adenylyltransferase and sulfurtransferase MOCS3; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] (460 aa)
MED21Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (158 aa)
CHRAC1CBFD_NFYB_HMF domain-containing protein. (131 aa)
POLR3ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1375 aa)
CRPPACDP-L-ribitol pyrophosphorylase A. (449 aa)
KARS1Lysine--tRNA ligase. (625 aa)
PCYT2Phosphate cytidylyltransferase 2, ethanolamine. (419 aa)
POLMDNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (494 aa)
FHITBis(5'-adenosyl)-triphosphatase. (149 aa)
POLBDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa)
POLR1BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1153 aa)
TENT4BTerminal nucleotidyltransferase 4B. (695 aa)
TEP1Telomerase associated protein 1. (2623 aa)
POLR2LRNA polymerase II subunit L. (67 aa)
POLR2CRNA polymerase II subunit C. (275 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (534 aa)
POLR3KDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (108 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
TENT5BTerminal nucleotidyltransferase 5B. (425 aa)
CDS1Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (461 aa)
SELENOOSelenoprotein O. (663 aa)
NMNAT3Nicotinamide-nucleotide adenylyltransferase. (252 aa)
TUT4Terminal uridylyl transferase 4. (1494 aa)
TWISTNBTWIST neighbor. (340 aa)
DNTTDNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. (509 aa)
HAUS3HAUS augmin like complex subunit 3. (603 aa)
ARID3AAT-rich interaction domain 3A. (594 aa)
ENSCCAP00000039839Uncharacterized protein. (342 aa)
CTU1Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position; Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily. (348 aa)
POLHDNA polymerase eta. (710 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1. (784 aa)
UGP2UTP--glucose-1-phosphate uridylyltransferase. (517 aa)
FPGTFucose-1-phosphate guanylyltransferase. (607 aa)
REV3LREV3 like, DNA directed polymerase zeta catalytic subunit. (2752 aa)
UAP1UDP-N-acetylglucosamine pyrophosphorylase 1. (522 aa)
POLR3BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1133 aa)
POLKDNA polymerase kappa. (863 aa)
YRDCYrdC N6-threonylcarbamoyltransferase domain containing. (363 aa)
NMNAT2Nicotinamide nucleotide adenylyltransferase 2. (307 aa)
PAPSS13'-phosphoadenosine 5'-phosphosulfate synthase 1. (624 aa)
OASL2'-5'-oligoadenylate synthetase like. (515 aa)
PCYT1APhosphate cytidylyltransferase 1, choline, alpha. (380 aa)
DKC1Dyskerin pseudouridine synthase 1. (470 aa)
MB21D2Mab-21 domain containing 2. (491 aa)
REV1DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1254 aa)
POLR3CRNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (534 aa)
PAPOLGPoly(A) polymerase gamma. (736 aa)
CDS2Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (445 aa)
POLQDNA polymerase theta. (2324 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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