STRINGSTRING
CDK1 CDK1 ROCK2 ROCK2 ENSCCAP00000013464 ENSCCAP00000013464 CAMK1D CAMK1D MARK2 MARK2 NLK NLK MKNK2 MKNK2 SLC1A1 SLC1A1 LOC108303723 LOC108303723 MAPKAPK5 MAPKAPK5 HMGA2 HMGA2 GSK3B GSK3B MAPK1 MAPK1 ULK1 ULK1 SRPK2 SRPK2 MAPK13 MAPK13 TDGF1 TDGF1 GRK2 GRK2 CSNK2A2 CSNK2A2 PBK PBK STK4 STK4 DCLK2 DCLK2 PIKFYVE PIKFYVE MAPK7 MAPK7 AURKB AURKB IL24 IL24 ENSCCAP00000019143 ENSCCAP00000019143 PLK1 PLK1 LOC108289705 LOC108289705 MAST2 MAST2 STK32A STK32A MAPKAPK2 MAPKAPK2 MARK1 MARK1 PRKCZ PRKCZ AKT2 AKT2 RPS6KA5 RPS6KA5 CDK2 CDK2 MTOR MTOR CSNK1G1 CSNK1G1 RPS6KB2 RPS6KB2 MARK3 MARK3 RICTOR RICTOR ATM ATM STK38L STK38L PRKAA1 PRKAA1 PRKDC PRKDC PRKG2 PRKG2 IKBKE IKBKE CAB39 CAB39 RPS6KA4 RPS6KA4 VRK1 VRK1 CAMK4 CAMK4 PINK1 PINK1 MAP3K20 MAP3K20 ENSCCAP00000023996 ENSCCAP00000023996 TOP1 TOP1 MST1 MST1 PRKCE PRKCE SGK2 SGK2 DYRK4 DYRK4 STK32B STK32B TTBK1 TTBK1 EIF2AK3 EIF2AK3 TLK2 TLK2 DGKQ DGKQ PDGFB PDGFB SBK1 SBK1 VRK3 VRK3 RIPK1 RIPK1 GAS6 GAS6 HIPK4 HIPK4 MAPK14 MAPK14 TSSK4 TSSK4 MAPK12 MAPK12 AURKC AURKC RPS6KA2 RPS6KA2 PRKD2 PRKD2 CAMK2D CAMK2D TTBK2 TTBK2 HIPK3 HIPK3 TGFBR1 TGFBR1 EPO EPO CAMK1 CAMK1 CHUK CHUK CAMK1G CAMK1G UHMK1 UHMK1 NTRK2 NTRK2 PRKCQ PRKCQ MAP3K13 MAP3K13 DCLK3 DCLK3 ERN1 ERN1 HIPK2 HIPK2 MYO3A MYO3A MYO3B MYO3B TLK1 TLK1 AKT1 AKT1 MAPK8 MAPK8 PRKAA2 PRKAA2 PRKD1 PRKD1 CDC7 CDC7 MAST1 MAST1 PRKCB PRKCB PCK1 PCK1 PKN3 PKN3 CSNK1A1 CSNK1A1 MAP3K12 MAP3K12 RPS6KA3 RPS6KA3 STK39 STK39 BRSK1 BRSK1 ENSCCAP00000038181 ENSCCAP00000038181 DYRK2 DYRK2 RPS6KA1 RPS6KA1 PDPK1 PDPK1 ULK2 ULK2 LOC108303195 LOC108303195 MAST3 MAST3 ATR ATR BAK1 BAK1 PKD1 PKD1 MAPK9 MAPK9 GSK3A GSK3A MASTL MASTL ROCK1 ROCK1 CSNK2A1 CSNK2A1 AKT3 AKT3 TBK1 TBK1 LOC108313439 LOC108313439 PRKCI PRKCI MAST4-2 MAST4-2 CHEK2 CHEK2 ENSCCAP00000011420 ENSCCAP00000011420 PRKCA PRKCA ENSCCAP00000011942 ENSCCAP00000011942 LOC108315475 LOC108315475 BRSK2 BRSK2 MAPKAPK3 MAPKAPK3 MAP3K10 MAP3K10 SMG1 SMG1 PKN1 PKN1 DYRK1A DYRK1A IKBKB IKBKB PAK2 PAK2 TGFBR2 TGFBR2 DYRK1B DYRK1B PKN2 PKN2 AURKA AURKA SRC SRC LMTK2 LMTK2 LRRK2 LRRK2 NEK7 NEK7 CLK1 CLK1 PNCK PNCK CAMKV CAMKV MAPK10 MAPK10 ULK3 ULK3 ENSCCAP00000006464 ENSCCAP00000006464 MAST4 MAST4 CDK5 CDK5 CLSPN CLSPN TNKS TNKS PDK3 PDK3 BCL2 BCL2 ENSCCAP00000005270 ENSCCAP00000005270 RPS6KB1 RPS6KB1 LATS2 LATS2 MAP4K1 MAP4K1 RPS6KA6 RPS6KA6 WNK1 WNK1 TSSK6 TSSK6 SYK SYK NEK6 NEK6 SMTNL1 SMTNL1 PLK2 PLK2 PRKCD PRKCD DCLK1 DCLK1 DMPK DMPK LOC108298062 LOC108298062 CDK5R1 CDK5R1 LATS1 LATS1 VRK2 VRK2 STK32C STK32C MKNK1 MKNK1 HIPK1 HIPK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1365 aa)
ENSCCAP00000013464Protein kinase domain-containing protein. (387 aa)
CAMK1DCalcium/calmodulin dependent protein kinase ID; Belongs to the protein kinase superfamily. (385 aa)
MARK2Non-specific serine/threonine protein kinase. (785 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
MKNK2MAPK interacting serine/threonine kinase 2. (509 aa)
SLC1A1Amino acid transporter. (524 aa)
LOC108303723Protein kinase domain-containing protein. (251 aa)
MAPKAPK5MAPK activated protein kinase 5. (473 aa)
HMGA2Uncharacterized protein. (118 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (434 aa)
MAPK1Mitogen-activated protein kinase. (366 aa)
ULK1Unc-51 like autophagy activating kinase 1. (964 aa)
SRPK2SRSF protein kinase 2. (698 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
TDGF1Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (187 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (689 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (350 aa)
PBKPDZ binding kinase. (323 aa)
STK4Serine/threonine kinase 4. (487 aa)
DCLK2Doublecortin like kinase 2. (783 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2098 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (816 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (344 aa)
IL24Interleukin 24. (206 aa)
ENSCCAP00000019143Protein kinase domain-containing protein. (402 aa)
PLK1Serine/threonine-protein kinase PLK. (602 aa)
LOC108289705Protein kinase domain-containing protein. (221 aa)
MAST2Microtubule associated serine/threonine kinase 2. (1800 aa)
STK32ASerine/threonine kinase 32A; Belongs to the protein kinase superfamily. (397 aa)
MAPKAPK2MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (401 aa)
MARK1Non-specific serine/threonine protein kinase. (795 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (605 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
RPS6KA5Ribosomal protein S6 kinase. (800 aa)
CDK2Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
MTORSerine/threonine-protein kinase mTOR. (2508 aa)
CSNK1G1Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. (475 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (486 aa)
MARK3Non-specific serine/threonine protein kinase. (753 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1732 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3000 aa)
STK38LNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (464 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4130 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (716 aa)
CAB39Calcium binding protein 39. (341 aa)
RPS6KA4Ribosomal protein S6 kinase. (777 aa)
VRK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (399 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (473 aa)
PINK1PTEN induced kinase 1. (581 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (800 aa)
ENSCCAP00000023996Protein kinase domain-containing protein. (243 aa)
TOP1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (767 aa)
MST1Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa)
PRKCEProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
SGK2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (409 aa)
DYRK4Dual specificity tyrosine phosphorylation regulated kinase 4; Belongs to the protein kinase superfamily. (480 aa)
STK32BSerine/threonine kinase 32B; Belongs to the protein kinase superfamily. (412 aa)
TTBK1Tau tubulin kinase 1. (1322 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1114 aa)
TLK2Tousled like kinase 2. (772 aa)
DGKQDiacylglycerol kinase. (938 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
SBK1Serine/threonine-protein kinase SBK1; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (426 aa)
VRK3VRK serine/threonine kinase 3. (472 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (671 aa)
GAS6Growth arrest specific 6. (676 aa)
HIPK4Homeodomain interacting protein kinase 4. (616 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
TSSK4Testis specific serine kinase 4. (339 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
AURKCProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (309 aa)
RPS6KA2Ribosomal protein S6 kinase. (758 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (860 aa)
CAMK2DCalcium/calmodulin dependent protein kinase II delta. (533 aa)
TTBK2Tau tubulin kinase 2. (1243 aa)
HIPK3Homeodomain interacting protein kinase 3. (1216 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (496 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (194 aa)
CAMK1Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily. (370 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (761 aa)
CAMK1GCalcium/calmodulin dependent protein kinase IG; Belongs to the protein kinase superfamily. (476 aa)
UHMK1U2AF homology motif kinase 1. (419 aa)
NTRK2Tyrosine-protein kinase receptor. (838 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (710 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (965 aa)
DCLK3Doublecortin like kinase 3. (817 aa)
ERN1Endoplasmic reticulum to nucleus signaling 1. (967 aa)
HIPK2Homeodomain interacting protein kinase 2. (1189 aa)
MYO3AMyosin IIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1614 aa)
MYO3BMyosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1340 aa)
TLK1Tousled like kinase 1. (785 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (489 aa)
MAPK8Mitogen-activated protein kinase. (384 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (884 aa)
CDC7Cell division cycle 7. (575 aa)
MAST1Microtubule associated serine/threonine kinase 1. (1588 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (669 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
PKN3Protein kinase N3. (889 aa)
CSNK1A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (365 aa)
MAP3K12Mitogen-activated protein kinase kinase kinase 12; May be an activator of the JNK/SAPK pathway. (893 aa)
RPS6KA3Non-specific serine/threonine protein kinase. (693 aa)
STK39Serine/threonine kinase 39. (542 aa)
BRSK1BR serine/threonine kinase 1. (794 aa)
ENSCCAP00000038181Protein kinase domain-containing protein. (293 aa)
DYRK2Dual specificity tyrosine phosphorylation regulated kinase 2. (601 aa)
RPS6KA1Ribosomal protein S6 kinase. (729 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (562 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1022 aa)
LOC108303195Protein kinase domain-containing protein. (309 aa)
MAST3Microtubule associated serine/threonine kinase 3. (1216 aa)
ATRATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4246 aa)
MAPK9Mitogen-activated protein kinase. (392 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa)
MASTLMicrotubule associated serine/threonine kinase like. (880 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (399 aa)
AKT3AKT serine/threonine kinase 3. (472 aa)
TBK1TANK binding kinase 1. (729 aa)
LOC108313439Protein kinase domain-containing protein. (247 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
MAST4-2Uncharacterized protein. (217 aa)
CHEK2Checkpoint kinase 2. (589 aa)
ENSCCAP00000011420Uncharacterized protein. (342 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (672 aa)
ENSCCAP00000011942Protein kinase domain-containing protein. (258 aa)
LOC108315475C2 domain-containing protein. (141 aa)
BRSK2BR serine/threonine kinase 2. (763 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (427 aa)
MAP3K10Mitogen-activated protein kinase kinase kinase. (952 aa)
SMG1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3521 aa)
PKN1Protein kinase N1. (945 aa)
DYRK1ADual specificity tyrosine phosphorylation regulated kinase 1A. (763 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
PAK2Non-specific serine/threonine protein kinase. (524 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (593 aa)
DYRK1BDual specificity tyrosine phosphorylation regulated kinase 1B. (629 aa)
PKN2Protein kinase N2. (983 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (401 aa)
SRCTyrosine-protein kinase. (542 aa)
LMTK2Lemur tyrosine kinase 2. (1501 aa)
LRRK2Leucine rich repeat kinase 2. (2526 aa)
NEK7Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (302 aa)
CLK1CDC like kinase 1. (517 aa)
PNCKPregnancy up-regulated nonubiquitous CaM kinase; Belongs to the protein kinase superfamily. (416 aa)
CAMKVCaM kinase like vesicle associated. (498 aa)
MAPK10Mitogen-activated protein kinase. (538 aa)
ULK3Unc-51 like kinase 3. (480 aa)
ENSCCAP00000006464Uncharacterized protein. (60 aa)
MAST4Microtubule associated serine/threonine kinase family member 4. (2420 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (322 aa)
CLSPNClaspin. (1336 aa)
TNKSPoly [ADP-ribose] polymerase. (1325 aa)
PDK3Protein-serine/threonine kinase. (415 aa)
BCL2BCL2 apoptosis regulator. (240 aa)
ENSCCAP00000005270Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (389 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
LATS2Non-specific serine/threonine protein kinase. (1085 aa)
MAP4K1Mitogen-activated protein kinase kinase kinase kinase 1; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (821 aa)
RPS6KA6Ribosomal protein S6 kinase. (741 aa)
WNK1WNK lysine deficient protein kinase 1. (2832 aa)
TSSK6Testis specific serine kinase 6; Belongs to the protein kinase superfamily. (273 aa)
SYKSpleen associated tyrosine kinase. (636 aa)
NEK6NIMA related kinase 6; Belongs to the protein kinase superfamily. (347 aa)
SMTNL1Smoothelin like 1. (499 aa)
PLK2Polo like kinase 2. (566 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
DCLK1Uncharacterized protein. (740 aa)
DMPKDM1 protein kinase. (630 aa)
LOC108298062Uncharacterized protein. (312 aa)
CDK5R1Cyclin-dependent kinase 5 activator. (307 aa)
LATS1Large tumor suppressor kinase 1. (1129 aa)
VRK2VRK serine/threonine kinase 2. (510 aa)
STK32CSerine/threonine kinase 32C; Belongs to the protein kinase superfamily. (486 aa)
MKNK1Protein kinase domain-containing protein. (458 aa)
HIPK1Homeodomain interacting protein kinase 1. (1210 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.