78 items (Cebus capucinus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	UBA6	Ubiquitin like modifier activating enzyme 6. (1052 aa)
	SMO	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (789 aa)
	MAS1	MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. (325 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	ZIC1	Zic family member 1. (447 aa)
	ENSCCAP00000000866	Uncharacterized protein. (141 aa)
	ENSCCAP00000000807	Uncharacterized protein. (144 aa)
	CDK5R1	Cyclin-dependent kinase 5 activator. (307 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
	RELN	Reelin. (3278 aa)
	SRF	Serum response factor. (509 aa)
	HTR5A	5-hydroxytryptamine receptor 5A. (357 aa)
	BCAN	Brevican. (911 aa)
	OGDH	Oxoglutarate dehydrogenase. (1038 aa)
	KIF14	Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1651 aa)
	NKX2-1	NK2 homeobox 1. (402 aa)
	NF2	Neurofibromin 2. (595 aa)
	TMEM108	Transmembrane protein 108. (575 aa)
	CRKL	CRK like proto-oncogene, adaptor protein. (303 aa)
	FGF13	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
	PROX1	Prospero homeobox 1. (737 aa)
	UQCRQ	Ubiquinol-cytochrome c reductase complex III subunit VII. (82 aa)
	YWHAE	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (208 aa)
	EMX2	Empty spiracles homeobox 2. (252 aa)
	NR2E1	Nuclear receptor subfamily 2 group E member 1. (421 aa)
	ALK	Tyrosine-protein kinase receptor. (1621 aa)
	BBS2	Bardet-Biedl syndrome 2. (614 aa)
	SCT	Secretin. (132 aa)
	CDK6	Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
	PTPRS	Protein tyrosine phosphatase receptor type S. (1948 aa)
	SEMA6B	Semaphorin 6B; Belongs to the semaphorin family. (891 aa)
	CRK	CRK proto-oncogene, adaptor protein. (304 aa)
	ANXA3	Annexin. (304 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1285 aa)
	MDK	Uncharacterized protein. (144 aa)
	MFSD2A	Major facilitator superfamily domain containing 2A. (543 aa)
	GLI3	GLI family zinc finger 3. (1577 aa)
	ENSCCAP00000023536	PTN_MK_N domain-containing protein. (92 aa)
	PLXNA3	Plexin A3. (1871 aa)
	ENSCCAP00000022251	Uncharacterized protein. (336 aa)
	EIF2B5	Eukaryotic translation initiation factor 2B subunit epsilon. (728 aa)
	LOC108301104	3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (372 aa)
	TSC1	TSC complex subunit 1. (1149 aa)
	PPP1R9B	Protein phosphatase 1 regulatory subunit 9B. (815 aa)
	LRP8	LDL receptor related protein 8. (958 aa)
	DLX1	Distal-less homeobox 1. (255 aa)
	ATAT1	Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] (423 aa)
	DCX	Doublecortin. (365 aa)
	ATP2B4	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1224 aa)
	KIRREL3	Kirre like nephrin family adhesion molecule 3. (783 aa)
	DCLK2	Doublecortin like kinase 2. (783 aa)
	ENSCCAP00000017839	Uncharacterized protein. (136 aa)
	EPHA5	EPH receptor A5. (1038 aa)
	LOC108297130	3Beta_HSD domain-containing protein; Belongs to the 3-beta-HSD family. (373 aa)
	ID4	Inhibitor of DNA binding 4, HLH protein. (161 aa)
	MKKS	McKusick-Kaufman syndrome. (570 aa)
	ZIC3	Zic family member 3. (467 aa)
	FAM205A	Family with sequence similarity 205 member A. (1334 aa)
	TENT2	Terminal nucleotidyltransferase 2. (484 aa)
	GSK3B	Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (434 aa)
	FEZF2	FEZ family zinc finger 2. (463 aa)
	BBS4	Bardet-Biedl syndrome 4. (494 aa)
	LMX1A	LIM homeobox transcription factor 1 alpha. (382 aa)
	DLX2	Distal-less homeobox 2. (328 aa)
	LEF1	Lymphoid enhancer binding factor 1. (399 aa)
	ENSCCAP00000009165	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (249 aa)
	RARA	Retinoic acid receptor alpha. (464 aa)
	BTG2	BTG anti-proliferation factor 2. (158 aa)
	PTEN	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
	BBS1	BBS1 domain-containing protein. (593 aa)
	ENSCCAP00000006464	Uncharacterized protein. (60 aa)
	CDK5	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (322 aa)
	PHLPP2	PH domain and leucine rich repeat protein phosphatase 2. (1355 aa)
	ENSCCAP00000005634	Hist_deacetyl domain-containing protein. (305 aa)
	NEUROD6	Neurogenic differentiation factor. (337 aa)
	NEUROD1	Neurogenic differentiation factor. (356 aa)
	FEZ1	Fasciculation and elongation protein zeta 1. (392 aa)
	CDK5R2	Cyclin-dependent kinase 5 activator. (367 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALK	CRK	ENSCCAP00000031150	ENSCCAP00000028287	Tyrosine-protein kinase receptor.	CRK proto-oncogene, adaptor protein.	0.468
ALK	CRKL	ENSCCAP00000031150	ENSCCAP00000035612	Tyrosine-protein kinase receptor.	CRK like proto-oncogene, adaptor protein.	0.470
ALK	ENSCCAP00000000807	ENSCCAP00000031150	ENSCCAP00000000807	Tyrosine-protein kinase receptor.	Uncharacterized protein.	0.643
ALK	ENSCCAP00000000866	ENSCCAP00000031150	ENSCCAP00000000866	Tyrosine-protein kinase receptor.	Uncharacterized protein.	0.643
ALK	ENSCCAP00000017839	ENSCCAP00000031150	ENSCCAP00000017839	Tyrosine-protein kinase receptor.	Uncharacterized protein.	0.643
ALK	ENSCCAP00000023536	ENSCCAP00000031150	ENSCCAP00000023536	Tyrosine-protein kinase receptor.	PTN_MK_N domain-containing protein.	0.643
ALK	MDK	ENSCCAP00000031150	ENSCCAP00000024850	Tyrosine-protein kinase receptor.	Uncharacterized protein.	0.643
ALK	PTEN	ENSCCAP00000031150	ENSCCAP00000007387	Tyrosine-protein kinase receptor.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.472
BBS1	BBS2	ENSCCAP00000006504	ENSCCAP00000030645	BBS1 domain-containing protein.	Bardet-Biedl syndrome 2.	0.993
BBS1	BBS4	ENSCCAP00000006504	ENSCCAP00000014204	BBS1 domain-containing protein.	Bardet-Biedl syndrome 4.	0.992
BBS1	MKKS	ENSCCAP00000006504	ENSCCAP00000016549	BBS1 domain-containing protein.	McKusick-Kaufman syndrome.	0.400
BBS1	SMO	ENSCCAP00000006504	ENSCCAP00000002443	BBS1 domain-containing protein.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.778
BBS2	BBS1	ENSCCAP00000030645	ENSCCAP00000006504	Bardet-Biedl syndrome 2.	BBS1 domain-containing protein.	0.993
BBS2	BBS4	ENSCCAP00000030645	ENSCCAP00000014204	Bardet-Biedl syndrome 2.	Bardet-Biedl syndrome 4.	0.995
BBS2	MKKS	ENSCCAP00000030645	ENSCCAP00000016549	Bardet-Biedl syndrome 2.	McKusick-Kaufman syndrome.	0.422
BBS2	SMO	ENSCCAP00000030645	ENSCCAP00000002443	Bardet-Biedl syndrome 2.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.670
BBS4	BBS1	ENSCCAP00000014204	ENSCCAP00000006504	Bardet-Biedl syndrome 4.	BBS1 domain-containing protein.	0.992
BBS4	BBS2	ENSCCAP00000014204	ENSCCAP00000030645	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 2.	0.995
BBS4	SMO	ENSCCAP00000014204	ENSCCAP00000002443	Bardet-Biedl syndrome 4.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.654
CDK5	CDK5R1	ENSCCAP00000006190	ENSCCAP00000000225	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	Cyclin-dependent kinase 5 activator.	0.993