(61 nodes) Myofibril assembly network (Cebus capucinus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108293231	IF rod domain-containing protein; Belongs to the intermediate filament family. (383 aa)
	CSRP1	Uncharacterized protein. (168 aa)
	NEBL	Nebulette. (977 aa)
	WDR1	WD repeat domain 1. (606 aa)
	LOC108307020	IF rod domain-containing protein; Belongs to the intermediate filament family. (354 aa)
	MYPN	Myopalladin. (1320 aa)
	ACTL10	Actin like 10; Belongs to the actin family. (245 aa)
	LMOD1	Leiomodin 1. (584 aa)
	MYLK3	Myosin light chain kinase 3. (819 aa)
	MYOZ2	Myozenin 2. (264 aa)
	MYOZ1	Myozenin 1. (299 aa)
	SYNPO2L	Synaptopodin 2 like. (978 aa)
	NRAP	Nebulin related anchoring protein. (1730 aa)
	SIX4	SIX homeobox 4. (781 aa)
	LMOD2	Leiomodin 2. (548 aa)
	MYH11	Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2012 aa)
	BMP10	Bone morphogenetic protein 10. (424 aa)
	KLHL41	Kelch like family member 41. (606 aa)
	TNNT2	Troponin T2, cardiac type. (298 aa)
	TMOD2	Tropomodulin 2. (351 aa)
	FLNC	Filamin C. (2709 aa)
	ENSCCAP00000011458	LIM zinc-binding domain-containing protein. (159 aa)
	MYH7	Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1793 aa)
	MYOM2	Myomesin 2. (1434 aa)
	ACTC1	Actin alpha cardiac muscle 1. (377 aa)
	LDB3	LIM domain binding 3. (732 aa)
	LOC108289653	Uncharacterized protein. (181 aa)
	LMOD3	Leiomodin 3. (561 aa)
	CSRP2	Uncharacterized protein. (243 aa)
	MYL9	Myosin light chain 9. (129 aa)
	NKX2-5	NK2 homeobox 5. (324 aa)
	KRT19	IF rod domain-containing protein; Belongs to the intermediate filament family. (400 aa)
	ACTN2	Actinin alpha 2. (895 aa)
	C10orf113	Chromosome 10 open reading frame 113. (106 aa)
	ADPRHL1	ADP-ribosylhydrolase like 1. (354 aa)
	ANKRD1	Ankyrin repeat domain 1. (319 aa)
	CAPN3	Calpain 3; Belongs to the peptidase C2 family. (816 aa)
	TMOD4	Tropomodulin 4. (345 aa)
	PLEC	Plectin. (4683 aa)
	PDGFRB	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1108 aa)
	OBSL1	Obscurin like 1. (1896 aa)
	TNNT3	Troponin T3, fast skeletal type. (269 aa)
	TMOD1	Tropomodulin 1. (359 aa)
	PGM5	Phosphoglucomutase 5; Belongs to the phosphohexose mutase family. (567 aa)
	OBSCN	Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF. (8516 aa)
	MYH6	Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1629 aa)
	FHOD3	Formin homology 2 domain containing 3. (1623 aa)
	TNNT1	Troponin T1, slow skeletal type. (241 aa)
	TTN	Uncharacterized protein. (27115 aa)
	PROX1	Prospero homeobox 1. (737 aa)
	MYH3	Myosin heavy chain 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1940 aa)
	ACTA1	Actin alpha 1, skeletal muscle. (377 aa)
	TCAP	Titin-cap. (167 aa)
	CASQ1	Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (398 aa)
	FLII	FLII actin remodeling protein. (1276 aa)
	MEF2A	Myocyte enhancer factor 2A. (502 aa)
	ENSCCAP00000037656	Uncharacterized protein. (184 aa)
	TMOD3	Tropomodulin 3. (352 aa)
	CFL2	Cofilin 2; Belongs to the actin-binding proteins ADF family. (166 aa)
	SRF	Serum response factor. (509 aa)
	CSRP3	Cysteine and glycine rich protein 3. (194 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTA1	ACTN2	ENSCCAP00000035521	ENSCCAP00000025117	Actin alpha 1, skeletal muscle.	Actinin alpha 2.	0.414
ACTA1	CFL2	ENSCCAP00000035521	ENSCCAP00000038979	Actin alpha 1, skeletal muscle.	Cofilin 2; Belongs to the actin-binding proteins ADF family.	0.715
ACTA1	LMOD1	ENSCCAP00000035521	ENSCCAP00000005122	Actin alpha 1, skeletal muscle.	Leiomodin 1.	0.710
ACTA1	MYH11	ENSCCAP00000035521	ENSCCAP00000009597	Actin alpha 1, skeletal muscle.	Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.707
ACTA1	MYH3	ENSCCAP00000035521	ENSCCAP00000034565	Actin alpha 1, skeletal muscle.	Myosin heavy chain 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.440
ACTA1	MYH6	ENSCCAP00000035521	ENSCCAP00000030362	Actin alpha 1, skeletal muscle.	Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.862
ACTA1	MYH7	ENSCCAP00000035521	ENSCCAP00000011989	Actin alpha 1, skeletal muscle.	Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.862
ACTA1	MYL9	ENSCCAP00000035521	ENSCCAP00000022365	Actin alpha 1, skeletal muscle.	Myosin light chain 9.	0.832
ACTA1	TMOD1	ENSCCAP00000035521	ENSCCAP00000028417	Actin alpha 1, skeletal muscle.	Tropomodulin 1.	0.676
ACTA1	TNNT2	ENSCCAP00000035521	ENSCCAP00000010033	Actin alpha 1, skeletal muscle.	Troponin T2, cardiac type.	0.936
ACTA1	WDR1	ENSCCAP00000035521	ENSCCAP00000001890	Actin alpha 1, skeletal muscle.	WD repeat domain 1.	0.601
ACTC1	ACTN2	ENSCCAP00000013075	ENSCCAP00000025117	Actin alpha cardiac muscle 1.	Actinin alpha 2.	0.414
ACTC1	CFL2	ENSCCAP00000013075	ENSCCAP00000038979	Actin alpha cardiac muscle 1.	Cofilin 2; Belongs to the actin-binding proteins ADF family.	0.715
ACTC1	LMOD1	ENSCCAP00000013075	ENSCCAP00000005122	Actin alpha cardiac muscle 1.	Leiomodin 1.	0.710
ACTC1	MYH11	ENSCCAP00000013075	ENSCCAP00000009597	Actin alpha cardiac muscle 1.	Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.707
ACTC1	MYH3	ENSCCAP00000013075	ENSCCAP00000034565	Actin alpha cardiac muscle 1.	Myosin heavy chain 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.440
ACTC1	MYH6	ENSCCAP00000013075	ENSCCAP00000030362	Actin alpha cardiac muscle 1.	Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.862
ACTC1	MYH7	ENSCCAP00000013075	ENSCCAP00000011989	Actin alpha cardiac muscle 1.	Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.862
ACTC1	MYL9	ENSCCAP00000013075	ENSCCAP00000022365	Actin alpha cardiac muscle 1.	Myosin light chain 9.	0.832
ACTC1	TMOD1	ENSCCAP00000013075	ENSCCAP00000028417	Actin alpha cardiac muscle 1.	Tropomodulin 1.	0.676