(45 nodes) Negative regulation of axon extension network (Cebus capucinus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

co-expression

protein homology

Your Input:
	NTN1	Netrin 1. (604 aa)
	RTN4	Reticulon. (1194 aa)
	MAP2	Microtubule-associated protein. (1830 aa)
	SEMA4F	Ssemaphorin 4F; Belongs to the semaphorin family. (770 aa)
	KIAA0319	KIAA0319. (1072 aa)
	NRP1	Neuropilin; Belongs to the neuropilin family. (927 aa)
	BCL11A	BAF chromatin remodeling complex subunit BCL11A. (835 aa)
	RNF6	Ring finger protein 6. (685 aa)
	SEMA4G	Semaphorin 4G; Belongs to the semaphorin family. (844 aa)
	SEMA4C	Semaphorin 4C; Belongs to the semaphorin family. (874 aa)
	DIP2B	Disco interacting protein 2 homolog B. (1542 aa)
	PTPRS	Protein tyrosine phosphatase receptor type S. (1948 aa)
	SEMA4A	Semaphorin 4A; Belongs to the semaphorin family. (661 aa)
	SEMA3A	Semaphorin 3A; Belongs to the semaphorin family. (772 aa)
	IFRD1	Uncharacterized protein. (451 aa)
	SEMA6B	Semaphorin 6B; Belongs to the semaphorin family. (891 aa)
	SEMA5B	Semaphorin 5B. (1179 aa)
	SEMA3D	Semaphorin 3D; Belongs to the semaphorin family. (723 aa)
	MAG	Myelin associated glycoprotein. (626 aa)
	SEMA3G	Semaphorin 3G; Belongs to the semaphorin family. (782 aa)
	SEMA4D	Semaphorin 4D; Belongs to the semaphorin family. (862 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
	TRIM46	Tripartite motif containing 46. (759 aa)
	DRAXIN	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (350 aa)
	RTN4R	Reticulon 4 receptor. (474 aa)
	SEMA3F	Semaphorin 3F; Belongs to the semaphorin family. (786 aa)
	CDK5	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (322 aa)
	ENSCCAP00000006464	Uncharacterized protein. (60 aa)
	SEMA6A	Semaphorin 6A; Belongs to the semaphorin family. (1047 aa)
	IFRD2	Interferon related developmental regulator 2. (507 aa)
	SEMA6C	Semaphorin 6C; Belongs to the semaphorin family. (962 aa)
	SLIT1	Slit guidance ligand 1. (1534 aa)
	SEMA4B	Semaphorin 4B; Belongs to the semaphorin family. (835 aa)
	SEMA7A	Semaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (661 aa)
	ARHGAP4	Rho GTPase activating protein 4. (966 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	RYK	Receptor like tyrosine kinase. (613 aa)
	ENSCCAP00000018918	Uncharacterized protein. (406 aa)
	TNR	Tenascin R. (1358 aa)
	SEMA3B	Semaphorin 3B; Belongs to the semaphorin family. (755 aa)
	SEMA3E	Semaphorin 3E; Belongs to the semaphorin family. (774 aa)
	MT3	Metallothionein 3; Belongs to the metallothionein superfamily. Type 1 family. (113 aa)
	SEMA5A	Semaphorin 5A. (1074 aa)
	PLXNA3	Plexin A3. (1871 aa)
	WNT3	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDK5	MAP2	ENSCCAP00000006190	ENSCCAP00000040523	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	Microtubule-associated protein.	0.809
CDK5	NRP1	ENSCCAP00000006190	ENSCCAP00000039756	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	Neuropilin; Belongs to the neuropilin family.	0.602
CDK5	SEMA3A	ENSCCAP00000006190	ENSCCAP00000029260	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	Semaphorin 3A; Belongs to the semaphorin family.	0.548
CDK5	SEMA3B	ENSCCAP00000006190	ENSCCAP00000021021	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	Semaphorin 3B; Belongs to the semaphorin family.	0.524
DRAXIN	NTN1	ENSCCAP00000003530	ENSCCAP00000025768	Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.	Netrin 1.	0.900
ENSCCAP00000006464	MAP2	ENSCCAP00000006464	ENSCCAP00000040523	Uncharacterized protein.	Microtubule-associated protein.	0.809
ENSCCAP00000006464	NRP1	ENSCCAP00000006464	ENSCCAP00000039756	Uncharacterized protein.	Neuropilin; Belongs to the neuropilin family.	0.602
ENSCCAP00000006464	SEMA3A	ENSCCAP00000006464	ENSCCAP00000029260	Uncharacterized protein.	Semaphorin 3A; Belongs to the semaphorin family.	0.548
ENSCCAP00000006464	SEMA3B	ENSCCAP00000006464	ENSCCAP00000021021	Uncharacterized protein.	Semaphorin 3B; Belongs to the semaphorin family.	0.524
MAG	RTN4	ENSCCAP00000026166	ENSCCAP00000025328	Myelin associated glycoprotein.	Reticulon.	0.777
MAG	RTN4R	ENSCCAP00000026166	ENSCCAP00000003668	Myelin associated glycoprotein.	Reticulon 4 receptor.	0.651
MAP2	CDK5	ENSCCAP00000040523	ENSCCAP00000006190	Microtubule-associated protein.	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	0.809
MAP2	ENSCCAP00000006464	ENSCCAP00000040523	ENSCCAP00000006464	Microtubule-associated protein.	Uncharacterized protein.	0.809
MAP2	NTN1	ENSCCAP00000040523	ENSCCAP00000025768	Microtubule-associated protein.	Netrin 1.	0.455
NRP1	CDK5	ENSCCAP00000039756	ENSCCAP00000006190	Neuropilin; Belongs to the neuropilin family.	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	0.602
NRP1	ENSCCAP00000006464	ENSCCAP00000039756	ENSCCAP00000006464	Neuropilin; Belongs to the neuropilin family.	Uncharacterized protein.	0.602
NRP1	PLXNA3	ENSCCAP00000039756	ENSCCAP00000022845	Neuropilin; Belongs to the neuropilin family.	Plexin A3.	0.989
NRP1	SEMA3A	ENSCCAP00000039756	ENSCCAP00000029260	Neuropilin; Belongs to the neuropilin family.	Semaphorin 3A; Belongs to the semaphorin family.	0.998
NRP1	SEMA3B	ENSCCAP00000039756	ENSCCAP00000021021	Neuropilin; Belongs to the neuropilin family.	Semaphorin 3B; Belongs to the semaphorin family.	0.989
NRP1	SEMA3D	ENSCCAP00000039756	ENSCCAP00000026770	Neuropilin; Belongs to the neuropilin family.	Semaphorin 3D; Belongs to the semaphorin family.	0.977