(117 nodes) Leukocyte chemotaxis network (Cebus capucinus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108292199	C-X-C motif chemokine. (102 aa)
	PDGFB	Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
	ANXA1	Annexin. (346 aa)
	CTSG	Cathepsin G; Belongs to the peptidase S1 family. (256 aa)
	CCL8	C-C motif chemokine ligand 8. (99 aa)
	MDK	Uncharacterized protein. (144 aa)
	PLA2G1B	Phospholipase A(2). (70 aa)
	DPEP1	Dipeptidase; Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family. (410 aa)
	CCL17	C-C motif chemokine. (102 aa)
	CXCL10	C-X-C motif chemokine. (96 aa)
	ENSCCAP00000023536	PTN_MK_N domain-containing protein. (92 aa)
	S100A8	Protein S100; Belongs to the S-100 family. (89 aa)
	CXCR5	C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. (372 aa)
	LBP	Lipopolysaccharide binding protein. (481 aa)
	EDN3	Endothelin 3. (230 aa)
	ANO6	Anoctamin. (934 aa)
	TNFSF14	TNF superfamily member 14. (240 aa)
	S100A9	S100 calcium binding protein A9; Belongs to the S-100 family. (110 aa)
	ALOX5	Arachidonate 5-lipoxygenase. (674 aa)
	CYP7B1	Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (505 aa)
	TNFRSF11A	TNF receptor superfamily member 11a. (617 aa)
	CSF3R	Colony stimulating factor 3 receptor. (836 aa)
	TRPM4	Transient receptor potential cation channel subfamily M member 4. (1214 aa)
	CXCL16	C-X-C motif chemokine ligand 16. (253 aa)
	PF4	C-X-C motif chemokine. (102 aa)
	ADAM8	ADAM metallopeptidase domain 8. (846 aa)
	CXCL17	C-X-C motif chemokine ligand 17. (119 aa)
	CCL24	C-C motif chemokine ligand 24. (119 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
	ARHGEF5	Rho guanine nucleotide exchange factor 5. (1595 aa)
	CCL1	SCY domain-containing protein. (96 aa)
	PIKFYVE	Phosphoinositide kinase, FYVE-type zinc finger containing. (2098 aa)
	ENSCCAP00000017839	Uncharacterized protein. (136 aa)
	CCL26	C-C motif chemokine ligand 26. (93 aa)
	MSMP	Beta-microseminoprotein. (139 aa)
	CCL25	C-C motif chemokine ligand 25. (149 aa)
	S100A12	S100 calcium binding protein A12; Belongs to the S-100 family. (92 aa)
	NINJ1	Ninjurin 1. (152 aa)
	IL17RA	Interleukin 17 receptor A. (861 aa)
	CCR7	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
	IL16	Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1246 aa)
	CXCL9	C-X-C motif chemokine. (129 aa)
	CXCL11	C-X-C motif chemokine. (94 aa)
	CCL14	C-C motif chemokine. (96 aa)
	TAFA4	TAFA chemokine like family member 4. (140 aa)
	EDNRB	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (509 aa)
	CCR6	C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (377 aa)
	VAV3	Vav guanine nucleotide exchange factor 3. (875 aa)
	ENSCCAP00000009774	Uncharacterized protein. (758 aa)
	LOC108292198	C-X-C motif chemokine. (107 aa)
	CORO1A	Coronin; Belongs to the WD repeat coronin family. (461 aa)
	LOC108312133	SCY domain-containing protein. (103 aa)
	LOC108292194	C-X-C motif chemokine. (107 aa)
	ITGA9	Integrin subunit alpha 9; Belongs to the integrin alpha chain family. (1035 aa)
	PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1056 aa)
	TNFSF11	Tumor necrosis factor ligand superfamily member. (317 aa)
	CXCL12	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
	AZU1	Azurocidin 1. (251 aa)
	PDE4B	Phosphodiesterase. (736 aa)
	CXADR	CXADR Ig-like cell adhesion molecule. (365 aa)
	SBDS	SBDS ribosome maturation factor. (250 aa)
	PREX1	Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1651 aa)
	S1PR1	Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (380 aa)
	LYST	Lysosomal trafficking regulator. (3802 aa)
	SYK	Spleen associated tyrosine kinase. (636 aa)
	PIP5K1C	Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma. (707 aa)
	HSD3B7	Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; Belongs to the 3-beta-HSD family. (369 aa)
	CCL2	C-C motif chemokine. (99 aa)
	ITGA1	Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
	PTPRO	Protein tyrosine phosphatase receptor type O. (1216 aa)
	PPBP	C-X-C motif chemokine. (128 aa)
	LOC108308386	SCY domain-containing protein. (85 aa)
	ENSCCAP00000000866	Uncharacterized protein. (141 aa)
	ENSCCAP00000000807	Uncharacterized protein. (144 aa)
	CXCL8	Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
	EDN2	Endothelin 2. (178 aa)
	ITGB2	Integrin beta. (770 aa)
	CCL20	C-C motif chemokine. (96 aa)
	C10orf99	Chromosome 10 open reading frame 99. (81 aa)
	SLAMF8	SLAM family member 8. (285 aa)
	XCL1	SCY domain-containing protein. (114 aa)
	BSG	Basigin (Ok blood group). (385 aa)
	CCL5	C-C motif chemokine. (91 aa)
	LGALS3	Galectin. (264 aa)
	PTN	Uncharacterized protein. (168 aa)
	CKLF	Chemokine like factor. (151 aa)
	CHGA	Chromogranin A. (456 aa)
	C5AR1	Complement C5a receptor 1; Belongs to the G-protein coupled receptor 1 family. (347 aa)
	TRPM2	Transient receptor potential cation channel subfamily M member 2. (1503 aa)
	TREM1	Triggering receptor expressed on myeloid cells 1. (235 aa)
	GBF1	Golgi brefeldin A resistant guanine nucleotide exchange factor 1. (1833 aa)
	FLT1	Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa)
	IL6R	Interleukin 6 receptor. (468 aa)
	CCL3L3	C-C motif chemokine. (93 aa)
	CCL21	C-C motif chemokine ligand 21. (154 aa)
	CX3CL1	C-X3-C motif chemokine ligand 1. (335 aa)
	ENSCCAP00000036868	Uncharacterized protein. (201 aa)
	JAML	Uncharacterized protein. (393 aa)
	CXCL13	C-X-C motif chemokine ligand 13. (99 aa)
	CXCR3	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (377 aa)
	PPIB	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
	SLC37A4	Solute carrier family 37 member 4. (451 aa)
	CCL22	C-C motif chemokine. (92 aa)
	NUP85	Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (667 aa)
	CCL16	C-C motif chemokine. (89 aa)
	LOC108293848	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (854 aa)
	GAS6	Growth arrest specific 6. (676 aa)
	PLEC	Plectin. (4683 aa)
	CCL19	C-C motif chemokine. (98 aa)
	NCKAP1L	NCK associated protein 1 like. (1084 aa)
	IL17RC	Interleukin 17 receptor C. (786 aa)
	CXCL6	C-X-C motif chemokine. (115 aa)
	VAV1	Uncharacterized protein. (899 aa)
	PIK3CG	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1102 aa)
	SLC12A2	Solute carrier family 12 member 2. (1209 aa)
	KIT	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
	SLAMF1	Signaling lymphocytic activation molecule family member 1. (357 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALOX5	PLA2G1B	ENSCCAP00000021643	ENSCCAP00000024608	Arachidonate 5-lipoxygenase.	Phospholipase A(2).	0.755
ANXA1	LGALS3	ENSCCAP00000025223	ENSCCAP00000032877	Annexin.	Galectin.	0.441
AZU1	CTSG	ENSCCAP00000006588	ENSCCAP00000025198	Azurocidin 1.	Cathepsin G; Belongs to the peptidase S1 family.	0.856
AZU1	LBP	ENSCCAP00000006588	ENSCCAP00000023028	Azurocidin 1.	Lipopolysaccharide binding protein.	0.414
BSG	PPIB	ENSCCAP00000032545	ENSCCAP00000039294	Basigin (Ok blood group).	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.634
CCL1	CCL16	ENSCCAP00000018376	ENSCCAP00000026178	SCY domain-containing protein.	C-C motif chemokine.	0.684
CCL1	CCL17	ENSCCAP00000018376	ENSCCAP00000024362	SCY domain-containing protein.	C-C motif chemokine.	0.595
CCL1	CCL2	ENSCCAP00000018376	ENSCCAP00000003909	SCY domain-containing protein.	C-C motif chemokine.	0.518
CCL1	CCL20	ENSCCAP00000018376	ENSCCAP00000000096	SCY domain-containing protein.	C-C motif chemokine.	0.442
CCL1	CCL21	ENSCCAP00000018376	ENSCCAP00000036794	SCY domain-containing protein.	C-C motif chemokine ligand 21.	0.409
CCL1	CCL22	ENSCCAP00000018376	ENSCCAP00000026078	SCY domain-containing protein.	C-C motif chemokine.	0.493
CCL1	CCL24	ENSCCAP00000018376	ENSCCAP00000018741	SCY domain-containing protein.	C-C motif chemokine ligand 24.	0.469
CCL1	CCL25	ENSCCAP00000018376	ENSCCAP00000015528	SCY domain-containing protein.	C-C motif chemokine ligand 25.	0.562
CCL1	CCL3L3	ENSCCAP00000018376	ENSCCAP00000036015	SCY domain-containing protein.	C-C motif chemokine.	0.470
CCL1	CCL5	ENSCCAP00000018376	ENSCCAP00000032822	SCY domain-containing protein.	C-C motif chemokine.	0.683
CCL1	CCR6	ENSCCAP00000018376	ENSCCAP00000010705	SCY domain-containing protein.	C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family.	0.877
CCL1	CCR7	ENSCCAP00000018376	ENSCCAP00000014079	SCY domain-containing protein.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.823
CCL1	CX3CL1	ENSCCAP00000018376	ENSCCAP00000036814	SCY domain-containing protein.	C-X3-C motif chemokine ligand 1.	0.506
CCL1	CXCL10	ENSCCAP00000018376	ENSCCAP00000023782	SCY domain-containing protein.	C-X-C motif chemokine.	0.829
CCL1	CXCL11	ENSCCAP00000018376	ENSCCAP00000012894	SCY domain-containing protein.	C-X-C motif chemokine.	0.806