Your Input: | |
| | RRAGD | Ras related GTP binding D. (404 aa) |
| | TNFAIP8L1 | TNF alpha induced protein 8 like 1. (186 aa) |
| | RRAGA | Uncharacterized protein. (313 aa) |
| | FNIP1 | Folliculin interacting protein 1. (1134 aa) |
| | PKHD1 | PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4074 aa) |
| | SLC38A9 | Solute carrier family 38 member 9. (561 aa) |
| | ENSCCAP00000001719 | CCHC-type domain-containing protein. (199 aa) |
| | LIN28A | CCHC-type domain-containing protein. (209 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa) |
| | RFFL | Ring finger and FYVE like domain containing E3 ubiquitin protein ligase. (363 aa) |
| | NPRL2 | NPR2 like, GATOR1 complex subunit. (383 aa) |
| | RNF152 | Ring finger protein 152. (203 aa) |
| | MLST8 | MTOR associated protein, LST8 homolog. (326 aa) |
| | C9orf72 | C9orf72-SMCR8 complex subunit. (481 aa) |
| | AKT1S1 | AKT1 substrate 1. (276 aa) |
| | HTR6 | 5-hydroxytryptamine receptor 6; Belongs to the G-protein coupled receptor 1 family. (440 aa) |
| | SH3BP4 | SH3 domain binding protein 4. (963 aa) |
| | LOC108298753 | Uncharacterized protein. (242 aa) |
| | TREM2 | Triggering receptor expressed on myeloid cells 2. (230 aa) |
| | GPR137 | G protein-coupled receptor 137. (458 aa) |
| | DEPTOR | DEP domain containing MTOR interacting protein. (409 aa) |
| | TMEM130 | Transmembrane protein 130. (435 aa) |
| | BMT2 | S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] (405 aa) |
| | AKT3 | AKT serine/threonine kinase 3. (472 aa) |
| | ENSCCAP00000011133 | Uncharacterized protein. (517 aa) |
| | TELO2 | Telomere maintenance 2. (837 aa) |
| | HDAC3 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa) |
| | ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (479 aa) |
| | ENSCCAP00000013704 | Uncharacterized protein. (156 aa) |
| | ENSCCAP00000014272 | Uncharacterized protein. (1147 aa) |
| | MAPKAPK5 | MAPK activated protein kinase 5. (473 aa) |
| | SESN1 | Sestrin 1. (543 aa) |
| | KLHL22 | Kelch like family member 22. (634 aa) |
| | RRAGB | Ras related GTP binding B. (374 aa) |
| | TBC1D7 | TBC1 domain family member 7. (293 aa) |
| | ENSCCAP00000016922 | Uncharacterized protein. (277 aa) |
| | LAMTOR2 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (125 aa) |
| | EPM2A | EPM2A glucan phosphatase, laforin. (331 aa) |
| | SEC13 | SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (368 aa) |
| | GSK3A | Glycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa) |
| | GPR137B | G protein-coupled receptor 137B. (399 aa) |
| | RELN | Reelin. (3278 aa) |
| | TSC2 | TSC complex subunit 2. (1777 aa) |
| | ENSCCAP00000038386 | CCHC-type domain-containing protein. (197 aa) |
| | WDR24 | WD repeat domain 24. (913 aa) |
| | DYRK3 | Dual specificity tyrosine phosphorylation regulated kinase 3. (588 aa) |
| | TTI1 | TELO2 interacting protein 1. (1088 aa) |
| | LAMTOR5 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (156 aa) |
| | RPTOR | Regulatory associated protein of MTOR complex 1. (1305 aa) |
| | SIK3 | Uncharacterized protein. (1322 aa) |
| | ARAF | A-Raf proto-oncogene, serine/threonine kinase. (606 aa) |
| | NPRL3 | NPR3 like, GATOR1 complex subunit. (582 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | SMCR8 | SMCR8-C9orf72 complex subunit. (937 aa) |
| | CASTOR2 | Uncharacterized protein. (329 aa) |
| | FBXO9 | F-box protein 9. (450 aa) |
| | ENSCCAP00000032229 | Uncharacterized protein. (91 aa) |
| | ROS1 | Tyrosine-protein kinase receptor. (2347 aa) |
| | TMEM127 | Transmembrane protein 127. (238 aa) |
| | UBR1 | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1070 aa) |
| | GPAT3 | Glycerol-3-phosphate acyltransferase 3. (434 aa) |
| | OTUD5 | OTU deubiquitinase 5. (567 aa) |
| | MIOS | Meiosis regulator for oocyte development. (875 aa) |
| | FLCN | Folliculin. (616 aa) |
| | ENSCCAP00000030087 | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (376 aa) |
| | RRAGC | Ras related GTP binding C. (399 aa) |
| | CTNS | Cystinosin, lysosomal cystine transporter. (400 aa) |
| | SESN2 | Sestrin 2. (480 aa) |
| | CRYBA1 | Crystallin beta A1; Belongs to the beta/gamma-crystallin family. (231 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1084 aa) |
| | WAC | WW domain containing adaptor with coiled-coil. (663 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) |
| | C12orf66 | Chromosome 12 open reading frame 66. (468 aa) |
| | SEH1L | SEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (422 aa) |
| | LOC108293547 | Uncharacterized protein. (773 aa) |
| | LAMTOR1 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa) |
| | ENSCCAP00000027253 | Uncharacterized protein. (75 aa) |
| | CLEC16A | C-type lectin domain containing 16A. (1053 aa) |
| | GAS6 | Growth arrest specific 6. (676 aa) |
| | SESN3 | Sestrin 3. (522 aa) |
| | CASTOR1 | Uncharacterized protein. (329 aa) |
| | RHEB | Ras homolog, mTORC1 binding. (184 aa) |
| | MINAR1 | Membrane integral NOTCH2 associated receptor 1. (916 aa) |
| | DGKQ | Diacylglycerol kinase. (938 aa) |
| | GOLPH3 | Golgi phosphoprotein 3. (298 aa) |
| | FAM83D | Family with sequence similarity 83 member D. (613 aa) |
| | DDIT4 | DNA damage inducible transcript 4. (232 aa) |
| | GPR137C | G protein-coupled receptor 137C. (429 aa) |
| | SIRT1 | Sirtuin 1. (446 aa) |
| | SZT2 | SZT2 subunit of KICSTOR complex. (3388 aa) |
| | GNA12 | G protein subunit alpha 12. (381 aa) |
| | XBP1 | BZIP domain-containing protein. (375 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (574 aa) |
| | HIF1A | Uncharacterized protein. (848 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3000 aa) |
| | RICTOR | RPTOR independent companion of MTOR complex 2. (1732 aa) |
| | ARNTL | Uncharacterized protein. (629 aa) |
| | TSC1 | TSC complex subunit 1. (1149 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | RNF167 | Ring finger protein 167. (352 aa) |
| | KPTN | Kaptin, actin binding protein. (427 aa) |
| | GBA | Glucosylceramidase. (536 aa) |
| | WDR59 | WD repeat domain 59. (974 aa) |
| | UBR2 | E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1755 aa) |
| | LAMTOR3 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa) |
| | PIH1D1 | PIH1 domain containing 1. (277 aa) |
| | LOC108317003 | Uncharacterized protein. (406 aa) |
| | LAMTOR4 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (99 aa) |
| | ITFG2 | Integrin alpha FG-GAP repeat containing 2. (444 aa) |
