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| | LOC108290368 | Nudix hydrolase domain-containing protein. (206 aa) |
| | NUDT13 | Nudix hydrolase 13. (352 aa) |
| | DNASE1L1 | Deoxyribonuclease; Belongs to the DNase I family. (302 aa) |
| | RNASEH1 | Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (288 aa) |
| | DIS3L | DIS3 like exosome 3'-5' exoribonuclease. (961 aa) |
| | GDA | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (472 aa) |
| | DDX5 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa) |
| | PNPT1 | Polyribonucleotide nucleotidyltransferase 1. (784 aa) |
| | LSM5 | U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa) |
| | LOC108297050 | Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (571 aa) |
| | POLR2D | RNA polymerase II subunit D. (142 aa) |
| | CDADC1 | Cytidine and dCMP deaminase domain containing 1. (515 aa) |
| | ZC3H4 | Zinc finger CCCH-type containing 4. (1303 aa) |
| | NUDT18 | Nudix hydrolase 18; Belongs to the Nudix hydrolase family. (323 aa) |
| | PDE10A | Phosphodiesterase. (787 aa) |
| | LSM5-4 | U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (77 aa) |
| | PABPC4 | Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (659 aa) |
| | PABPC3 | Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (631 aa) |
| | LSM1 | U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. (133 aa) |
| | METTL14 | Methyltransferase like 14; Belongs to the MT-A70-like family. (456 aa) |
| | ENSCCAP00000038386 | CCHC-type domain-containing protein. (197 aa) |
| | MLYCD | Malonyl-CoA decarboxylase. (493 aa) |
| | TUT4 | Terminal uridylyl transferase 4. (1494 aa) |
| | XRN2 | XRN_M domain-containing protein. (370 aa) |
| | CSDE1 | Uncharacterized protein. (844 aa) |
| | XDH | Xanthine dehydrogenase. (1333 aa) |
| | ENPP4 | Ectonucleotide pyrophosphatase/phosphodiesterase 4. (453 aa) |
| | OGG1 | 8-oxoguanine DNA glycosylase. (402 aa) |
| | ENSCCAP00000037661 | Uncharacterized protein. (119 aa) |
| | PAN2 | PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1202 aa) |
| | DXO | Decapping exoribonuclease. (396 aa) |
| | RBM7 | RRM domain-containing protein. (264 aa) |
| | LSM6 | Sm domain-containing protein. (80 aa) |
| | PDE5A | Phosphodiesterase. (875 aa) |
| | LSM4 | U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (139 aa) |
| | CNOT3 | CCR4-NOT transcription complex subunit 3. (754 aa) |
| | NUDT17 | Nudix hydrolase 17. (351 aa) |
| | PDE7B | Phosphodiesterase. (505 aa) |
| | MRTO4 | Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (239 aa) |
| | EIF4A3 | Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (428 aa) |
| | DIS3L2 | DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mi [...] (848 aa) |
| | ENPP3 | Ectonucleotide pyrophosphatase/phosphodiesterase 3. (878 aa) |
| | UPF2 | UPF2 regulator of nonsense mediated mRNA decay. (1234 aa) |
| | SMUG1 | Uncharacterized protein. (270 aa) |
| | DNASE2 | Deoxyribonuclease 2, lysosomal. (233 aa) |
| | ERN2 | Endoplasmic reticulum to nucleus signaling 2. (923 aa) |
| | SMG6 | SMG6 nonsense mediated mRNA decay factor. (1419 aa) |
| | NT5C3B | 5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (300 aa) |
| | ETF1 | eRF1_1 domain-containing protein. (423 aa) |
| | DCP1A | Decapping mRNA 1A. (581 aa) |
| | DNASE1L2 | Deoxyribonuclease; Belongs to the DNase I family. (299 aa) |
| | PDE8B | Phosphodiesterase. (885 aa) |
| | PELO | Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (385 aa) |
| | LSM7 | LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (102 aa) |
| | TENT4B | Terminal nucleotidyltransferase 4B. (695 aa) |
| | TTC38 | Tetratricopeptide repeat domain 38. (468 aa) |
| | SSB | Small RNA binding exonuclease protection factor La. (405 aa) |
| | ENSCCAP00000034367 | PAM2 domain-containing protein. (233 aa) |
| | SMG8 | SMG8 nonsense mediated mRNA decay factor. (991 aa) |
| | FHIT | Bis(5'-adenosyl)-triphosphatase. (149 aa) |
| | ERN1 | Endoplasmic reticulum to nucleus signaling 1. (967 aa) |
| | XRN1 | 5'-3' exoribonuclease 1. (1707 aa) |
| | NUDT15 | Nudix hydrolase 15. (164 aa) |
| | ENSCCAP00000033006 | UDG domain-containing protein. (282 aa) |
| | RNPS1 | RNA binding protein with serine rich domain 1. (305 aa) |
| | LRRC27 | Leucine rich repeat containing 27. (519 aa) |
| | DCP2 | Decapping mRNA 2. (441 aa) |
| | AGO3 | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa) |
| | PDE4C | Phosphodiesterase. (712 aa) |
| | CNOT2 | CCR4-NOT transcription complex subunit 2. (546 aa) |
| | ZFP36 | ZFP36 ring finger protein. (332 aa) |
| | METTL3 | Methyltransferase like 3; Belongs to the MT-A70-like family. (580 aa) |
| | TRIR | Telomerase RNA component interacting RNase. (176 aa) |
| | SUPV3L1 | Suv3 like RNA helicase. (766 aa) |
| | APOBEC2 | Apolipoprotein B mRNA editing enzyme catalytic subunit 2. (224 aa) |
| | SWT1 | SWT1 RNA endoribonuclease homolog. (901 aa) |
| | ENSCCAP00000031543 | CIDE-N domain-containing protein. (156 aa) |
| | MAGOH | Uncharacterized protein. (149 aa) |
| | CNOT6 | CCR4-NOT transcription complex subunit 6. (539 aa) |
| | ENSCCAP00000031241 | Uncharacterized protein. (387 aa) |
| | CASC3 | CASC3 exon junction complex subunit. (704 aa) |
| | ENSCCAP00000031091 | Uncharacterized protein. (66 aa) |
| | ZCCHC7 | Zinc finger CCHC-type containing 7. (543 aa) |
| | ENSCCAP00000030858 | S1 domain-containing protein. (182 aa) |
| | CECR2 | CECR2 histone acetyl-lysine reader. (1431 aa) |
| | LOC108315302 | Uncharacterized protein. (406 aa) |
| | HPRT1 | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa) |
| | APEX1 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (318 aa) |
| | TYMP | Thymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. (482 aa) |
| | EDC4 | Enhancer of mRNA decapping 4. (1406 aa) |
| | ENTPD1 | Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (522 aa) |
| | LOC108310148 | U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (79 aa) |
| | BCLAF1 | BCL2 associated transcription factor 1. (872 aa) |
| | ENSCCAP00000028972 | Uncharacterized protein. (361 aa) |
| | NCBP1 | Nuclear cap binding protein subunit 1. (790 aa) |
| | UPF1 | UPF1 RNA helicase and ATPase. (1151 aa) |
| | LOC108287793 | Uncharacterized protein. (368 aa) |
| | GSPT2 | G1 to S phase transition 2. (626 aa) |
| | LSM5-3 | U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa) |
| | CNOT7 | Uncharacterized protein. (285 aa) |
| | ENSCCAP00000028175 | Uncharacterized protein. (375 aa) |
| | DPYS | Dihydropyrimidinase. (519 aa) |
| | LOC108288088 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (305 aa) |
| | LRPPRC | PPR_long domain-containing protein. (1395 aa) |
| | LOC108298189 | Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (585 aa) |
| | PABPC4L | Poly(A) binding protein cytoplasmic 4 like. (428 aa) |
| | ENTPD7 | Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (605 aa) |
| | SAMD4B | Sterile alpha motif domain containing 4B. (694 aa) |
| | LOC108296834 | Uncharacterized protein. (514 aa) |
| | PDE12 | Phosphodiesterase 12. (547 aa) |
| | MTPAP | Mitochondrial poly(A) polymerase. (582 aa) |
| | DNASE2B | Deoxyribonuclease 2 beta. (361 aa) |
| | APOBEC3C | CMP/dCMP-type deaminase domain-containing protein. (221 aa) |
| | APOBEC3A | CMP/dCMP-type deaminase domain-containing protein. (206 aa) |
| | ENSCCAP00000026158 | CSD_1 domain-containing protein. (440 aa) |
| | VCP | Valosin containing protein; Belongs to the AAA ATPase family. (807 aa) |
| | DCPS | Decapping enzyme, scavenger. (354 aa) |
| | EXOSC9 | Exosome component 9. (442 aa) |
| | NT5C | 5', 3'-nucleotidase, cytosolic. (201 aa) |
| | AMPD3 | AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (777 aa) |
| | ADA | A_deaminase domain-containing protein. (363 aa) |
| | ADAL | Adenosine deaminase like. (355 aa) |
| | RNASEH2A | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (300 aa) |
| | FITM2 | Fat storage inducing transmembrane protein 2. (262 aa) |
| | AICDA | Activation induced cytidine deaminase. (183 aa) |
| | PARN | Poly(A)-specific ribonuclease. (639 aa) |
| | NUDT9 | Nudix hydrolase 9. (350 aa) |
| | NUDT5 | Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. (230 aa) |
| | ENSCCAP00000024871 | eRF1_1 domain-containing protein. (98 aa) |
| | CDA | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa) |
| | ENSCCAP00000024056 | Smg4_UPF3 domain-containing protein. (377 aa) |
| | MBD4 | Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein. (579 aa) |
| | UNG | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family. (313 aa) |
| | DIS3 | DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (959 aa) |
| | UPP1 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (310 aa) |
| | SUCLG2 | Succinate-CoA ligase GDP-forming beta subunit. (436 aa) |
| | EXOSC7 | Exosome component 7. (291 aa) |
| | PDE7A | Phosphodiesterase. (460 aa) |
| | DUT | Deoxyuridine triphosphatase. (250 aa) |
| | ZPR1 | ZPR1 zinc finger. (459 aa) |
| | DHX34 | DExH-box helicase 34. (1144 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3000 aa) |
| | SMG7 | SMG7 nonsense mediated mRNA decay factor. (1144 aa) |
| | RBM8A | RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa) |
| | NUDT19 | Nudix hydrolase 19. (376 aa) |
| | PNP | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa) |
| | ENSCCAP00000021366 | Uncharacterized protein. (489 aa) |
| | ENTPD8 | Ectonucleoside triphosphate diphosphohydrolase 8; Belongs to the GDA1/CD39 NTPase family. (494 aa) |
| | THRAP3 | Thyroid hormone receptor associated protein 3. (955 aa) |
| | TTC37 | Tetratricopeptide repeat domain 37. (1564 aa) |
| | ENDOG | Endonuclease. (285 aa) |
| | METTL16 | U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase; RNA N6-methyltransferase that methylates adenosine residues of a subset of RNAs and plays a key role in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6- methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure. In presence of S-adenosyl-L-methionine, binds the 3'-UTR region of MAT2A mRNA and specifical [...] (554 aa) |
| | NBAS | Neuroblastoma amplified sequence. (2372 aa) |
| | ENSCCAP00000020522 | Uncharacterized protein. (129 aa) |
| | PDE4A | Phosphodiesterase. (804 aa) |
| | ENTPD5 | Ectonucleoside triphosphate diphosphohydrolase 5 (inactive); Belongs to the GDA1/CD39 NTPase family. (427 aa) |
| | SIDT2 | SID1 transmembrane family member 2. (861 aa) |
| | HELZ2 | Helicase with zinc finger 2. (2644 aa) |
| | ENTPD2 | Ectonucleoside triphosphate diphosphohydrolase 2; Belongs to the GDA1/CD39 NTPase family. (495 aa) |
| | ENSCCAP00000019805 | Uncharacterized protein. (54 aa) |
| | PABPN1L | Poly(A) binding protein nuclear 1 like, cytoplasmic. (274 aa) |
| | CNOT11 | CCR4-NOT transcription complex subunit 11. (510 aa) |
| | NT5C3A | 5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family. (336 aa) |
| | LOC108295278 | Uncharacterized protein. (544 aa) |
| | LOC108289529 | Uncharacterized protein. (384 aa) |
| | SMG5 | SMG5 nonsense mediated mRNA decay factor. (1016 aa) |
| | ZFP36L2 | ZFP36 ring finger protein like 2. (493 aa) |
| | YTHDF2 | YTH N6-methyladenosine RNA binding protein 2. (587 aa) |
| | LOC108296489 | Phosphodiesterase. (726 aa) |
| | PDE8A | Phosphodiesterase. (836 aa) |
| | DICER1 | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1922 aa) |
| | REXO4 | REX4 homolog, 3'-5' exonuclease. (397 aa) |
| | RNASEH2B | Ribonuclease H2 subunit B. (309 aa) |
| | EIF3E | Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (473 aa) |
| | DNASE1 | Deoxyribonuclease; Belongs to the DNase I family. (282 aa) |
| | CNOT1 | CCR4-NOT transcription complex subunit 1. (2337 aa) |
| | DCP1B | Decapping mRNA 1B. (619 aa) |
| | SKIV2L | Ski2 like RNA helicase. (1246 aa) |
| | NUDT11 | Nudix hydrolase 11. (164 aa) |
| | PNLDC1 | PARN like, ribonuclease domain containing 1. (531 aa) |
| | PYM1 | PYM homolog 1, exon junction complex associated factor. (204 aa) |
| | CNOT8 | CCR4-NOT transcription complex subunit 8. (238 aa) |
| | RC3H1 | Ring finger and CCCH-type domains 1. (1120 aa) |
| | TENT2 | Terminal nucleotidyltransferase 2. (484 aa) |
| | EXOSC4 | Exosome component 4. (207 aa) |
| | DCTPP1 | dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. (170 aa) |
| | RNASEH2C | Ribonuclease H2 subunit C. (163 aa) |
| | ISG20 | Interferon stimulated exonuclease gene 20. (181 aa) |
| | NUDT12 | Nudix hydrolase 12. (462 aa) |
| | PPP1R8 | Protein phosphatase 1 regulatory subunit 8. (351 aa) |
| | LOC108299138 | Uncharacterized protein. (123 aa) |
| | KHSRP | KH-type splicing regulatory protein. (684 aa) |
| | PATL2 | PAT1 homolog 2. (537 aa) |
| | ENTPD3 | Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family. (529 aa) |
| | TUT7 | Uncharacterized protein. (1493 aa) |
| | CNOT6L | CCR4-NOT transcription complex subunit 6 like. (562 aa) |
| | ENSCCAP00000014300 | Uncharacterized protein. (364 aa) |
| | ENSCCAP00000014238 | HIT domain-containing protein. (89 aa) |
| | NUDT3 | Nudix hydrolase 3. (132 aa) |
| | NUDT8 | Nudix hydrolase domain-containing protein. (230 aa) |
| | CNOT4 | CCR4-NOT transcription complex subunit 4. (713 aa) |
| | SMG9 | SMG9 nonsense mediated mRNA decay factor. (520 aa) |
| | HNRNPD | Heterogeneous nuclear ribonucleoprotein D. (355 aa) |
| | DNASE1L3 | Deoxyribonuclease; Belongs to the DNase I family. (305 aa) |
| | WDR82 | WD repeat domain 82. (313 aa) |
| | UPB1 | Beta-ureidopropionase 1. (401 aa) |
| | LOC108284316 | Uncharacterized protein. (206 aa) |
| | LSM2 | U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa) |
| | SMG1 | SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3521 aa) |
| | ENSCCAP00000012572 | Uncharacterized protein. (137 aa) |
| | FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (345 aa) |
| | EXOSC1 | Exosome component 1. (169 aa) |
| | ZC3H12A | Zinc finger CCCH-type containing 12A. (598 aa) |
| | PATL1 | PAT1 homolog 1, processing body mRNA decay factor. (770 aa) |
| | ACAT1 | Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa) |
| | LOC108299224 | Uncharacterized protein. (106 aa) |
| | OAS2 | 2'-5'-oligoadenylate synthetase 2. (726 aa) |
| | EXOSC8 | Exosome component 8. (276 aa) |
| | EXOSC10 | Exosome component 10. (859 aa) |
| | FBH1 | F-box DNA helicase 1. (1080 aa) |
| | RIDA | Reactive intermediate imine deaminase A homolog. (164 aa) |
| | ENSCCAP00000010701 | Uncharacterized protein. (259 aa) |
| | ADA2 | Adenosine deaminase 2. (402 aa) |
| | ENSCCAP00000010495 | Phosphodiesterase. (755 aa) |
| | DERA | Deoxyribose-phosphate aldolase. (318 aa) |
| | ITPA | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. (207 aa) |
| | EXOG | Exo/endonuclease G. (368 aa) |
| | CTIF | Cap binding complex dependent translation initiation factor. (601 aa) |
| | NOCT | Nocturnin. (431 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1060 aa) |
| | LOC108291449 | RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (174 aa) |
| | SETMAR | SET domain and mariner transposase fusion gene. (684 aa) |
| | ENTPD4 | Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family. (616 aa) |
| | ENSCCAP00000009065 | Uncharacterized protein. (120 aa) |
| | NTHL1 | Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (312 aa) |
| | APOBEC1 | Apolipoprotein B mRNA editing enzyme catalytic subunit 1. (236 aa) |
| | ENSCCAP00000008669 | Uncharacterized protein. (275 aa) |
| | RNASET2 | Uncharacterized protein; Belongs to the RNase T2 family. (256 aa) |
| | NT5E | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (574 aa) |
| | ENSCCAP00000008476 | Smg4_UPF3 domain-containing protein. (272 aa) |
| | PDE4D | Phosphodiesterase. (808 aa) |
| | SMPDL3A | Acid sphingomyelinase-like phosphodiesterase. (453 aa) |
| | ENSCCAP00000008083 | Sm domain-containing protein. (63 aa) |
| | ENPP1 | Ectonucleotide pyrophosphatase/phosphodiesterase 1. (925 aa) |
| | ACOT7 | Uncharacterized protein. (380 aa) |
| | EDC3 | Enhancer of mRNA decapping 3. (508 aa) |
| | SAMHD1 | SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1. (509 aa) |
| | ENSCCAP00000007600 | RRM domain-containing protein. (163 aa) |
| | NUDT16 | Nudix hydrolase 16. (219 aa) |
| | DNPH1 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1; Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases. (207 aa) |
| | MAGOHB | Uncharacterized protein. (148 aa) |
| | PAN3 | PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (820 aa) |
| | SUCLG1 | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (346 aa) |
| | DFFA | DNA fragmentation factor subunit alpha. (331 aa) |
| | MUS81 | MUS81 structure-specific endonuclease subunit. (552 aa) |
| | UPP2 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (365 aa) |
| | LIN28B | Lin-28 homolog B. (262 aa) |
| | PDE2A | Phosphodiesterase. (944 aa) |
| | NEIL1 | Nei like DNA glycosylase 1. (390 aa) |
| | PDE4B | Phosphodiesterase. (736 aa) |
| | ENSCCAP00000005811 | Sm domain-containing protein. (80 aa) |
| | ENSCCAP00000005485 | Uncharacterized protein. (168 aa) |
| | NT5C1A | 5'-nucleotidase, cytosolic IA. (371 aa) |
| | ENSCCAP00000005127 | A_deaminase domain-containing protein. (260 aa) |
| | ENSCCAP00000004993 | Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. (193 aa) |
| | MLH1 | MutL homolog 1. (757 aa) |
| | TDG | Thymine DNA glycosylase. (410 aa) |
| | EXOSC2 | Exosome component 2. (293 aa) |
| | LOC108308846 | Uncharacterized protein. (235 aa) |
| | ABCD1 | ATP binding cassette subfamily D member 1. (744 aa) |
| | ZHX2 | Zinc fingers and homeoboxes 2. (837 aa) |
| | POP1 | POP1 homolog, ribonuclease P/MRP subunit. (1008 aa) |
| | UPF3A | UPF3A regulator of nonsense mediated mRNA decay. (476 aa) |
| | CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase. (474 aa) |
| | CNOT9 | Uncharacterized protein. (331 aa) |
| | NUDT7 | Nudix hydrolase 7. (238 aa) |
| | NBDY | Negative regulator of P-body association. (68 aa) |
| | MTREX | Mtr4 exosome RNA helicase. (1048 aa) |
| | MGAT1 | Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase. (445 aa) |
| | ZC3H12D | Zinc finger CCCH-type containing 12D. (529 aa) |
| | EXOSC5 | Exosome component 5. (235 aa) |
| | LIN28A | CCHC-type domain-containing protein. (209 aa) |
| | AGO1 | Argonaute RISC component 1; Belongs to the argonaute family. (857 aa) |
| | NUDT4 | Nudix hydrolase domain-containing protein. (181 aa) |
| | ENSCCAP00000001719 | CCHC-type domain-containing protein. (199 aa) |
| | EXOSC3 | Exosome component 3. (310 aa) |
| | APOBEC3H | Apolipoprotein B mRNA editing enzyme catalytic subunit 3H. (213 aa) |
| | ENSCCAP00000001306 | Phosphodiesterase. (694 aa) |
| | ENTPD6 | Ectonucleoside triphosphate diphosphohydrolase 6; Belongs to the GDA1/CD39 NTPase family. (482 aa) |
| | ZFP36L1 | ZFP36 ring finger protein like 1. (338 aa) |
| | SARM1 | Sterile alpha and TIR motif containing 1. (724 aa) |
| | HINT1 | Histidine triad nucleotide binding protein 1. (126 aa) |
| | DPYD | Dihydropyrimidine dehydrogenase [NADP(+)]; Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine; Belongs to the dihydropyrimidine dehydrogenase family. (996 aa) |
| | AGO4 | Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (861 aa) |
| | PDE9A | Phosphodiesterase. (624 aa) |
| | RC3H2 | Ring finger and CCCH-type domains 2. (1191 aa) |
| | ENSCCAP00000000247 | Uncharacterized protein. (73 aa) |
| | LSM5-2 | U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa) |
