(26 nodes) Response to prostaglandin E network (Cebus capucinus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	ADCY6	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1161 aa)
	LOC108298339	Uncharacterized protein. (164 aa)
	P2RY6	Pyrimidinergic receptor P2Y6. (328 aa)
	ACACA	Acetyl-CoA carboxylase alpha. (2383 aa)
	GNAS	GNAS complex locus. (1044 aa)
	FN1	Fibronectin 1. (2478 aa)
	LOC108315475	C2 domain-containing protein. (141 aa)
	PTGER2	Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (358 aa)
	ENSCCAP00000013944	Uncharacterized protein. (340 aa)
	CCR7	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
	ENSCCAP00000018301	Uncharacterized protein. (279 aa)
	LOC108298696	Uncharacterized protein. (349 aa)
	PPP1R9B	Protein phosphatase 1 regulatory subunit 9B. (815 aa)
	PRKAA1	Non-specific serine/threonine protein kinase. (574 aa)
	GNG2	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (110 aa)
	TGFBR3	Transforming growth factor beta receptor 3. (851 aa)
	PRKCE	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
	SFRP1	Secreted frizzled related protein 1. (314 aa)
	TNFSF4	TNF superfamily member 4; Belongs to the tumor necrosis factor family. (183 aa)
	CCL19	C-C motif chemokine. (98 aa)
	OXT	Oxytocin/neurophysin I prepropeptide. (125 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (489 aa)
	PRKAA2	Non-specific serine/threonine protein kinase. (552 aa)
	PTGER4	Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (490 aa)
	CCL21	C-C motif chemokine ligand 21. (154 aa)
	AKAP8	A-kinase anchoring protein 8; Belongs to the AKAP95 family. (651 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACACA	PRKAA1	ENSCCAP00000004979	ENSCCAP00000021862	Acetyl-CoA carboxylase alpha.	Non-specific serine/threonine protein kinase.	0.973
ACACA	PRKAA2	ENSCCAP00000004979	ENSCCAP00000034805	Acetyl-CoA carboxylase alpha.	Non-specific serine/threonine protein kinase.	0.955
ADCY6	AKT1	ENSCCAP00000012688	ENSCCAP00000034600	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.765
ADCY6	ENSCCAP00000013944	ENSCCAP00000012688	ENSCCAP00000013944	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.907
ADCY6	ENSCCAP00000018301	ENSCCAP00000012688	ENSCCAP00000018301	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.907
ADCY6	GNAS	ENSCCAP00000012688	ENSCCAP00000006125	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	GNAS complex locus.	0.907
ADCY6	GNG2	ENSCCAP00000012688	ENSCCAP00000022307	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.753
ADCY6	LOC108298339	ENSCCAP00000012688	ENSCCAP00000000879	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.907
ADCY6	LOC108298696	ENSCCAP00000012688	ENSCCAP00000019965	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein.	0.907
AKT1	ADCY6	ENSCCAP00000034600	ENSCCAP00000012688	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.765
AKT1	PRKAA1	ENSCCAP00000034600	ENSCCAP00000021862	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.434
AKT1	PRKAA2	ENSCCAP00000034600	ENSCCAP00000034805	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase.	0.439
CCL19	CCL21	ENSCCAP00000027947	ENSCCAP00000036794	C-C motif chemokine.	C-C motif chemokine ligand 21.	0.894
CCL19	CCR7	ENSCCAP00000027947	ENSCCAP00000014079	C-C motif chemokine.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.953
CCL21	CCL19	ENSCCAP00000036794	ENSCCAP00000027947	C-C motif chemokine ligand 21.	C-C motif chemokine.	0.894
CCL21	CCR7	ENSCCAP00000036794	ENSCCAP00000014079	C-C motif chemokine ligand 21.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.995
CCR7	CCL19	ENSCCAP00000014079	ENSCCAP00000027947	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine.	0.953
CCR7	CCL21	ENSCCAP00000014079	ENSCCAP00000036794	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine ligand 21.	0.995
ENSCCAP00000013944	ADCY6	ENSCCAP00000013944	ENSCCAP00000012688	Uncharacterized protein.	Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.907
ENSCCAP00000013944	GNG2	ENSCCAP00000013944	ENSCCAP00000022307	Uncharacterized protein.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.842