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ULK2 | Unc-51 like autophagy activating kinase 2. (1022 aa) | ||||
ATG7 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (707 aa) | ||||
ATG2A | Autophagy related 2A. (1941 aa) | ||||
ATG2B | Autophagy related 2B. (2079 aa) | ||||
ULK1 | Unc-51 like autophagy activating kinase 1. (964 aa) | ||||
RB1CC1 | RB1 inducible coiled-coil 1. (1594 aa) |