STRINGSTRING
PRICKLE1 PRICKLE1 SEC24B SEC24B JAG1 JAG1 ENSCCAP00000001480 ENSCCAP00000001480 ROBO1 ROBO1 HECTD1 HECTD1 ENSCCAP00000003834 ENSCCAP00000003834 EFEMP2 EFEMP2 MYLK MYLK PDE2A PDE2A LOC108285634 LOC108285634 DCTN5 DCTN5 ADAMTS6 ADAMTS6 SUFU SUFU CNTRL CNTRL CHD7 CHD7 ENG ENG PLXND1 PLXND1 DLL4 DLL4 FOXH1 FOXH1 SMAD6 SMAD6 TGFB2 TGFB2 TBX1 TBX1 LOXL1 LOXL1 FGF8 FGF8 HEY1 HEY1 LOC108309251 LOC108309251 NKX3-1 NKX3-1 ENSCCAP00000023868 ENSCCAP00000023868 COL3A1 COL3A1 EYA1 EYA1 FKBP10 FKBP10 PRDM1 PRDM1 ENSCCAP00000027253 ENSCCAP00000027253 PDGFRB PDGFRB ACVRL1 ACVRL1 SOX4 SOX4 LEP LEP NGFR NGFR EGR2 EGR2 LOC108291812 LOC108291812 PKD2 PKD2 LOX LOX LRP2 LRP2 ENSCCAP00000032767 ENSCCAP00000032767 BMPR1A BMPR1A ENSCCAP00000034192 ENSCCAP00000034192 AP2B1 AP2B1 PROX1 PROX1 NPRL3 NPRL3 EDNRA EDNRA ADAMTS9 ADAMTS9 HEY2 HEY2 TBX2 TBX2 TFAP2B TFAP2B NDST1 NDST1 ROBO2 ROBO2 LRP1 LRP1 SRF SRF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRICKLE1Prickle planar cell polarity protein 1. (829 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1244 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
ENSCCAP00000001480Uncharacterized protein. (68 aa)
ROBO1Roundabout guidance receptor 1. (1651 aa)
HECTD1HECT domain E3 ubiquitin protein ligase 1. (2610 aa)
ENSCCAP00000003834Ig-like domain-containing protein. (132 aa)
EFEMP2EGF containing fibulin extracellular matrix protein 2. (443 aa)
MYLKUncharacterized protein. (1859 aa)
PDE2APhosphodiesterase. (944 aa)
LOC108285634B2-adapt-app_C domain-containing protein. (254 aa)
DCTN5Uncharacterized protein. (164 aa)
ADAMTS6ADAM metallopeptidase with thrombospondin type 1 motif 6. (1117 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (522 aa)
CNTRLCentriolin. (2325 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2996 aa)
ENGEndoglin. (655 aa)
PLXND1Plexin D1. (1924 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
FOXH1Forkhead box H1. (365 aa)
SMAD6Mothers against decapentaplegic homolog. (489 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
TBX1T-box transcription factor 1. (495 aa)
LOXL1Lysyl oxidase like 1. (581 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (308 aa)
LOC108309251Uncharacterized protein. (490 aa)
NKX3-1NK3 homeobox 1. (223 aa)
ENSCCAP00000023868Uncharacterized protein. (144 aa)
COL3A1Collagen type III alpha 1 chain. (1465 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (610 aa)
FKBP10Peptidylprolyl isomerase. (532 aa)
PRDM1PR/SET domain 1. (825 aa)
ENSCCAP00000027253Uncharacterized protein. (75 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1108 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
SOX4Transcription factor SOX. (470 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
NGFRNerve growth factor receptor. (427 aa)
EGR2Early growth response 2. (473 aa)
LOC108291812Uncharacterized protein. (57 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (984 aa)
LOXLysyl oxidase. (417 aa)
LRP2LDL receptor related protein 2. (4656 aa)
ENSCCAP00000032767Uncharacterized protein. (680 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (432 aa)
ENSCCAP00000034192Uncharacterized protein. (68 aa)
AP2B1AP complex subunit beta. (899 aa)
PROX1Prospero homeobox 1. (737 aa)
NPRL3NPR3 like, GATOR1 complex subunit. (582 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif 9. (1935 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
TBX2T-box transcription factor 2. (713 aa)
TFAP2BTranscription factor AP-2 beta. (460 aa)
NDST1N-deacetylase and N-sulfotransferase 1. (882 aa)
ROBO2Roundabout guidance receptor 2. (1395 aa)
LRP1LDL receptor related protein 1. (4544 aa)
SRFSerum response factor. (509 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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