STRINGSTRING
SMYD1 SMYD1 EGR1 EGR1 ANKRD33 ANKRD33 MYLK2 MYLK2 MYOG MYOG NR4A1 NR4A1 MYOD1 MYOD1 BCL9L BCL9L HIVEP3 HIVEP3 KLF5 KLF5 NOTCH1 NOTCH1 MEF2D MEF2D SHH SHH COPS2 COPS2 NUPR1 NUPR1 GTF3C5 GTF3C5 PHOX2B PHOX2B ATF3 ATF3 EGR2 EGR2 ANKRD33B ANKRD33B MYF6 MYF6 ASB2 ASB2 SCX SCX SELENON SELENON FOXN2 FOXN2 ANKRD1 ANKRD1 MAFF MAFF MYF5 MYF5 HLF HLF EOMES EOMES MEGF10 MEGF10 LOC108294424 LOC108294424 BARX2 BARX2 KLHL40 KLHL40 DMRTA2 DMRTA2 FOS FOS EMD EMD HEYL HEYL BCL9 BCL9 SOX8 SOX8 KLHL41 KLHL41 SIX4 SIX4 BTG2 BTG2 HMG20B HMG20B CITED2 CITED2 ZNF689 ZNF689 RB1 RB1 SAP30 SAP30 WNT3A WNT3A LEMD2 LEMD2 SOX11 SOX11 PAX5 PAX5 CDON CDON
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMYD1SET and MYND domain containing 1. (490 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (543 aa)
ANKRD33Ankyrin repeat domain 33. (432 aa)
MYLK2Myosin light chain kinase 2. (596 aa)
MYOGMyogenin. (249 aa)
NR4A1Nuclear receptor subfamily 4 group A member 1. (652 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
BCL9LBCL9 like. (1497 aa)
HIVEP3Human immunodeficiency virus type I enhancer binding protein 3. (2402 aa)
KLF5Kruppel like factor 5. (457 aa)
NOTCH1Notch receptor 1. (2550 aa)
MEF2DMyocyte enhancer factor 2D. (521 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (464 aa)
COPS2COP9 signalosome subunit 2. (450 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (82 aa)
GTF3C5General transcription factor IIIC subunit 5. (529 aa)
PHOX2BPaired like homeobox 2B. (314 aa)
ATF3Activating transcription factor 3. (181 aa)
EGR2Early growth response 2. (473 aa)
ANKRD33BAnkyrin repeat domain 33B. (489 aa)
MYF6Myogenic factor 6. (242 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (635 aa)
SCXScleraxis bHLH transcription factor. (203 aa)
SELENONEF-hand domain-containing protein. (561 aa)
FOXN2Forkhead box N2. (431 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
MAFFMAF bZIP transcription factor F. (164 aa)
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)
HLFHLF transcription factor, PAR bZIP family member. (295 aa)
EOMESEomesodermin. (705 aa)
MEGF10Multiple EGF like domains 10. (1139 aa)
LOC108294424EF-hand domain-containing protein. (488 aa)
BARX2BARX homeobox 2. (279 aa)
KLHL40Kelch like family member 40. (619 aa)
DMRTA2DMRT like family A2. (537 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
EMDEmerin. (259 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
BCL9BCL9 transcription coactivator. (1426 aa)
SOX8SRY-box transcription factor 8. (446 aa)
KLHL41Kelch like family member 41. (606 aa)
SIX4SIX homeobox 4. (781 aa)
BTG2BTG anti-proliferation factor 2. (158 aa)
HMG20BHigh mobility group 20B. (348 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (275 aa)
ZNF689Zinc finger protein 689. (500 aa)
RB1RB transcriptional corepressor 1. (927 aa)
SAP30Sin3A associated protein 30. (220 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
LEMD2LEM domain containing 2. (503 aa)
SOX11Transcription factor SOX. (450 aa)
PAX5Paired box 5. (391 aa)
CDONCell adhesion associated, oncogene regulated. (1287 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.