STRINGSTRING
PDCD6IP PDCD6IP VPS37A VPS37A VPS25 VPS25 MVB12A MVB12A ENSCCAP00000011796 ENSCCAP00000011796 CHMP4C CHMP4C VPS4A VPS4A MVB12B MVB12B VPS37C VPS37C HGS HGS SNF8 SNF8 VPS28 VPS28 TSG101 TSG101 VPS37B VPS37B LOC108289809 LOC108289809 CHMP4B CHMP4B CHMP2A CHMP2A VPS36 VPS36 UBAP1 UBAP1 STAM STAM STAM2 STAM2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDCD6IPProgrammed cell death 6 interacting protein. (873 aa)
VPS37AVPS37A subunit of ESCRT-I. (397 aa)
VPS25Vacuolar protein sorting 25 homolog. (176 aa)
MVB12AMultivesicular body subunit 12A. (273 aa)
ENSCCAP00000011796VPS37 C-terminal domain-containing protein. (358 aa)
CHMP4CCharged multivesicular body protein 4C. (233 aa)
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
MVB12BMultivesicular body subunit 12B. (318 aa)
VPS37CVPS37C subunit of ESCRT-I. (357 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (802 aa)
SNF8SNF8 subunit of ESCRT-II. (299 aa)
VPS28Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (255 aa)
TSG101Tumor susceptibility 101. (395 aa)
VPS37BVPS37B subunit of ESCRT-I. (285 aa)
LOC108289809Uncharacterized protein. (87 aa)
CHMP4BCharged multivesicular body protein 4B. (224 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
VPS36Vacuolar protein sorting 36 homolog. (363 aa)
UBAP1Ubiquitin associated protein 1. (564 aa)
STAMSignal transducing adaptor molecule. (540 aa)
STAM2Signal transducing adaptor molecule 2. (534 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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