30 items (Cebus capucinus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EZR	Ezrin. (596 aa)
	BBS2	Bardet-Biedl syndrome 2. (614 aa)
	PLS1	Uncharacterized protein. (629 aa)
	SPTBN4	Spectrin beta chain; Belongs to the spectrin family. (2562 aa)
	SMO	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (789 aa)
	TSHR	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
	DRD2	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
	BCL2	BCL2 apoptosis regulator. (240 aa)
	GHRL	Ghrelin and obestatin prepropeptide. (117 aa)
	SLC6A3	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (687 aa)
	CREB1	cAMP responsive element binding protein 1. (341 aa)
	BBS4	Bardet-Biedl syndrome 4. (494 aa)
	HMGA2	Uncharacterized protein. (118 aa)
	PEX5	TPR_REGION domain-containing protein. (639 aa)
	CHD7	Chromodomain helicase DNA binding protein 7. (2996 aa)
	MKKS	McKusick-Kaufman syndrome. (570 aa)
	VIL1	Villin 1. (558 aa)
	IGF2	Insulin like growth factor 2. (236 aa)
	GPAM	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
	GHR	Growth hormone receptor. (638 aa)
	CSF1	Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (551 aa)
	GHSR	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
	ENSCCAP00000023346	Uncharacterized protein. (418 aa)
	ENSCCAP00000024566	Uncharacterized protein. (133 aa)
	GHRHR	Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
	ATP8A2	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1188 aa)
	GHRH	Growth hormone releasing hormone. (107 aa)
	STAT5B	Signal transducer and activator of transcription. (788 aa)
	NIPBL	Nipped-B protein. (2814 aa)
	PPIB	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BBS2	BBS4	ENSCCAP00000030645	ENSCCAP00000014204	Bardet-Biedl syndrome 2.	Bardet-Biedl syndrome 4.	0.995
BBS2	MKKS	ENSCCAP00000030645	ENSCCAP00000016549	Bardet-Biedl syndrome 2.	McKusick-Kaufman syndrome.	0.422
BBS2	SMO	ENSCCAP00000030645	ENSCCAP00000002443	Bardet-Biedl syndrome 2.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.670
BBS4	BBS2	ENSCCAP00000014204	ENSCCAP00000030645	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 2.	0.995
BBS4	SMO	ENSCCAP00000014204	ENSCCAP00000002443	Bardet-Biedl syndrome 4.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.654
BCL2	CREB1	ENSCCAP00000005426	ENSCCAP00000013792	BCL2 apoptosis regulator.	cAMP responsive element binding protein 1.	0.615
CREB1	BCL2	ENSCCAP00000013792	ENSCCAP00000005426	cAMP responsive element binding protein 1.	BCL2 apoptosis regulator.	0.615
DRD2	GHRL	ENSCCAP00000004749	ENSCCAP00000008994	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	Ghrelin and obestatin prepropeptide.	0.898
DRD2	SLC6A3	ENSCCAP00000004749	ENSCCAP00000012224	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.905
ENSCCAP00000023346	EZR	ENSCCAP00000023346	ENSCCAP00000022646	Uncharacterized protein.	Ezrin.	0.572
ENSCCAP00000024566	GPAM	ENSCCAP00000024566	ENSCCAP00000019089	Uncharacterized protein.	Glycerol-3-phosphate acyltransferase 1, mitochondrial.	0.455
EZR	ENSCCAP00000023346	ENSCCAP00000022646	ENSCCAP00000023346	Ezrin.	Uncharacterized protein.	0.572
EZR	PLS1	ENSCCAP00000022646	ENSCCAP00000000583	Ezrin.	Uncharacterized protein.	0.572
GHR	GHRH	ENSCCAP00000019762	ENSCCAP00000032824	Growth hormone receptor.	Growth hormone releasing hormone.	0.470
GHR	GHRHR	ENSCCAP00000019762	ENSCCAP00000031474	Growth hormone receptor.	Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family.	0.471
GHR	STAT5B	ENSCCAP00000019762	ENSCCAP00000035111	Growth hormone receptor.	Signal transducer and activator of transcription.	0.724
GHRH	GHR	ENSCCAP00000032824	ENSCCAP00000019762	Growth hormone releasing hormone.	Growth hormone receptor.	0.470
GHRH	GHRHR	ENSCCAP00000032824	ENSCCAP00000031474	Growth hormone releasing hormone.	Growth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family.	0.996
GHRH	GHRL	ENSCCAP00000032824	ENSCCAP00000008994	Growth hormone releasing hormone.	Ghrelin and obestatin prepropeptide.	0.709
GHRH	GHSR	ENSCCAP00000032824	ENSCCAP00000020603	Growth hormone releasing hormone.	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	0.594