48 items (Cebus capucinus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PICK1	Protein interacting with PRKCA 1. (415 aa)
	PRKAG1	Protein kinase AMP-activated non-catalytic subunit gamma 1. (331 aa)
	PIK3R4	Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa)
	NUAK2	NUAK family kinase 2. (628 aa)
	PIK3C3	Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
	BCL2	BCL2 apoptosis regulator. (240 aa)
	NIM1K	NIM1 serine/threonine protein kinase; Belongs to the protein kinase superfamily. (436 aa)
	LOC108298866	Perilipin; Belongs to the perilipin family. (453 aa)
	ZC3H12A	Zinc finger CCCH-type containing 12A. (598 aa)
	SLC7A5	Solute carrier family 7 member 5. (509 aa)
	BRSK2	BR serine/threonine kinase 2. (763 aa)
	PLIN2	Perilipin; Belongs to the perilipin family. (426 aa)
	SESN1	Sestrin 1. (543 aa)
	MYBBP1A	MYB binding protein 1a. (1321 aa)
	ENSCCAP00000017918	Perilipin; Belongs to the perilipin family. (387 aa)
	PMAIP1	Phorbol-12-myristate-13-acetate-induced protein 1. (54 aa)
	ITFG2	Integrin alpha FG-GAP repeat containing 2. (444 aa)
	LOC108291914	Perilipin; Belongs to the perilipin family. (449 aa)
	PLIN3	Perilipin; Belongs to the perilipin family. (392 aa)
	KPTN	Kaptin, actin binding protein. (427 aa)
	TBL2	Transducin beta like 2. (446 aa)
	SIK1	Uncharacterized protein. (791 aa)
	ATG14	Autophagy related 14. (510 aa)
	PRKAA1	Non-specific serine/threonine protein kinase. (574 aa)
	XBP1	BZIP domain-containing protein. (375 aa)
	HSPA5	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (654 aa)
	UPP1	Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (310 aa)
	SZT2	SZT2 subunit of KICSTOR complex. (3388 aa)
	SIRT1	Sirtuin 1. (446 aa)
	PRKAG2	Protein kinase AMP-activated non-catalytic subunit gamma 2. (569 aa)
	EIF2AK3	Eukaryotic translation initiation factor 2 alpha kinase 3. (1114 aa)
	SESN3	Sestrin 3. (522 aa)
	C12orf66	Chromosome 12 open reading frame 66. (468 aa)
	NUAK1	NUAK family kinase 1. (667 aa)
	SESN2	Sestrin 2. (480 aa)
	TP53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (395 aa)
	PRKAG3	Protein kinase AMP-activated non-catalytic subunit gamma 3. (487 aa)
	KAT5	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa)
	SLC2A1	Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (508 aa)
	NFE2L2	Nuclear factor, erythroid 2 like 2. (606 aa)
	MTMR3	Myotubularin related protein 3. (1220 aa)
	RRP8	Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (461 aa)
	PRKAA2	Non-specific serine/threonine protein kinase. (552 aa)
	CHKA	Choline kinase alpha. (453 aa)
	IMPACT	Impact RWD domain protein. (318 aa)
	BRSK1	BR serine/threonine kinase 1. (794 aa)
	CPEB4	Cytoplasmic polyadenylation element binding protein 4. (729 aa)
	ATF4	Activating transcription factor 4. (351 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATF4	EIF2AK3	ENSCCAP00000039804	ENSCCAP00000025055	Activating transcription factor 4.	Eukaryotic translation initiation factor 2 alpha kinase 3.	0.974
ATF4	HSPA5	ENSCCAP00000039804	ENSCCAP00000022508	Activating transcription factor 4.	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.	0.719
ATF4	NFE2L2	ENSCCAP00000039804	ENSCCAP00000031939	Activating transcription factor 4.	Nuclear factor, erythroid 2 like 2.	0.577
ATF4	SESN2	ENSCCAP00000039804	ENSCCAP00000029319	Activating transcription factor 4.	Sestrin 2.	0.613
ATF4	XBP1	ENSCCAP00000039804	ENSCCAP00000022213	Activating transcription factor 4.	BZIP domain-containing protein.	0.745
ATG14	BCL2	ENSCCAP00000021489	ENSCCAP00000005426	Autophagy related 14.	BCL2 apoptosis regulator.	0.562
ATG14	PIK3C3	ENSCCAP00000021489	ENSCCAP00000005213	Autophagy related 14.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.998
ATG14	PIK3R4	ENSCCAP00000021489	ENSCCAP00000003911	Autophagy related 14.	Phosphoinositide-3-kinase regulatory subunit 4.	0.998
ATG14	PRKAA1	ENSCCAP00000021489	ENSCCAP00000021862	Autophagy related 14.	Non-specific serine/threonine protein kinase.	0.575
ATG14	PRKAA2	ENSCCAP00000021489	ENSCCAP00000034805	Autophagy related 14.	Non-specific serine/threonine protein kinase.	0.573
ATG14	PRKAG2	ENSCCAP00000021489	ENSCCAP00000024073	Autophagy related 14.	Protein kinase AMP-activated non-catalytic subunit gamma 2.	0.554
BCL2	ATG14	ENSCCAP00000005426	ENSCCAP00000021489	BCL2 apoptosis regulator.	Autophagy related 14.	0.562
BCL2	HSPA5	ENSCCAP00000005426	ENSCCAP00000022508	BCL2 apoptosis regulator.	Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family.	0.444
BCL2	PIK3C3	ENSCCAP00000005426	ENSCCAP00000005213	BCL2 apoptosis regulator.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.590
BCL2	PMAIP1	ENSCCAP00000005426	ENSCCAP00000018097	BCL2 apoptosis regulator.	Phorbol-12-myristate-13-acetate-induced protein 1.	0.929
BCL2	SIRT1	ENSCCAP00000005426	ENSCCAP00000023626	BCL2 apoptosis regulator.	Sirtuin 1.	0.563
BCL2	TP53	ENSCCAP00000005426	ENSCCAP00000029525	BCL2 apoptosis regulator.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.981
BCL2	XBP1	ENSCCAP00000005426	ENSCCAP00000022213	BCL2 apoptosis regulator.	BZIP domain-containing protein.	0.455
C12orf66	ITFG2	ENSCCAP00000028369	ENSCCAP00000018331	Chromosome 12 open reading frame 66.	Integrin alpha FG-GAP repeat containing 2.	0.992
C12orf66	KPTN	ENSCCAP00000028369	ENSCCAP00000019821	Chromosome 12 open reading frame 66.	Kaptin, actin binding protein.	0.992