39 items (Cebus capucinus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TSG101	Tumor susceptibility 101. (395 aa)
	VPS28	Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (255 aa)
	MVB12B	Multivesicular body subunit 12B. (318 aa)
	VPS4A	Uncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
	UBAP1L	Ubiquitin associated protein 1 like. (358 aa)
	HDAC6	Histone deacetylase 6. (1213 aa)
	TOM1L1	Target of myb1 like 1 membrane trafficking protein; Belongs to the TOM1 family. (474 aa)
	LOC108284318	Uncharacterized protein. (194 aa)
	LOC108282717	UBP-type domain-containing protein. (1057 aa)
	CHMP2B	Charged multivesicular body protein 2B. (215 aa)
	VPS37A	VPS37A subunit of ESCRT-I. (397 aa)
	PLAA	Phospholipase A2 activating protein. (803 aa)
	RNF126	Ring finger protein 126. (311 aa)
	ENSCCAP00000008966	Uncharacterized protein. (183 aa)
	VPS25	Vacuolar protein sorting 25 homolog. (176 aa)
	MVB12A	Multivesicular body subunit 12A. (273 aa)
	ENSCCAP00000011796	VPS37 C-terminal domain-containing protein. (358 aa)
	ENSCCAP00000013648	Uncharacterized protein. (138 aa)
	RNF115	Ring finger protein 115. (284 aa)
	CHMP4C	Charged multivesicular body protein 4C. (233 aa)
	SNF8	SNF8 subunit of ESCRT-II. (299 aa)
	VPS36	Vacuolar protein sorting 36 homolog. (363 aa)
	ENSCCAP00000018340	Uncharacterized protein. (166 aa)
	CHMP5	Uncharacterized protein. (219 aa)
	LOC108310005	Uncharacterized protein. (221 aa)
	UBAP1	Ubiquitin associated protein 1. (564 aa)
	CHMP7	Charged multivesicular body protein 7. (453 aa)
	STAM	Signal transducing adaptor molecule. (540 aa)
	NEDD4	NEDD4 E3 ubiquitin protein ligase. (1319 aa)
	STAM2	Signal transducing adaptor molecule 2. (534 aa)
	CHMP6	Charged multivesicular body protein 6. (201 aa)
	HGS	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (802 aa)
	VPS37D	VPS37D subunit of ESCRT-I. (251 aa)
	CHMP2A	Charged multivesicular body protein 2A. (222 aa)
	PTPN23	Protein tyrosine phosphatase non-receptor type 23. (1651 aa)
	CHMP4B	Charged multivesicular body protein 4B. (224 aa)
	LOC108289809	Uncharacterized protein. (87 aa)
	CHMP1A	Charged multivesicular body protein 1A. (331 aa)
	VPS37B	VPS37B subunit of ESCRT-I. (285 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHMP1A	CHMP2A	ENSCCAP00000035245	ENSCCAP00000033976	Charged multivesicular body protein 1A.	Charged multivesicular body protein 2A.	0.994
CHMP1A	CHMP2B	ENSCCAP00000035245	ENSCCAP00000004442	Charged multivesicular body protein 1A.	Charged multivesicular body protein 2B.	0.954
CHMP1A	CHMP4B	ENSCCAP00000035245	ENSCCAP00000034980	Charged multivesicular body protein 1A.	Charged multivesicular body protein 4B.	0.986
CHMP1A	CHMP4C	ENSCCAP00000035245	ENSCCAP00000015056	Charged multivesicular body protein 1A.	Charged multivesicular body protein 4C.	0.979
CHMP1A	CHMP5	ENSCCAP00000035245	ENSCCAP00000018409	Charged multivesicular body protein 1A.	Uncharacterized protein.	0.949
CHMP1A	CHMP6	ENSCCAP00000035245	ENSCCAP00000026463	Charged multivesicular body protein 1A.	Charged multivesicular body protein 6.	0.974
CHMP1A	CHMP7	ENSCCAP00000035245	ENSCCAP00000020506	Charged multivesicular body protein 1A.	Charged multivesicular body protein 7.	0.963
CHMP1A	ENSCCAP00000008966	ENSCCAP00000035245	ENSCCAP00000008966	Charged multivesicular body protein 1A.	Uncharacterized protein.	0.949
CHMP1A	ENSCCAP00000011796	ENSCCAP00000035245	ENSCCAP00000011796	Charged multivesicular body protein 1A.	VPS37 C-terminal domain-containing protein.	0.765
CHMP1A	HGS	ENSCCAP00000035245	ENSCCAP00000026795	Charged multivesicular body protein 1A.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	0.671
CHMP1A	LOC108284318	ENSCCAP00000035245	ENSCCAP00000000993	Charged multivesicular body protein 1A.	Uncharacterized protein.	0.971
CHMP1A	LOC108289809	ENSCCAP00000035245	ENSCCAP00000035067	Charged multivesicular body protein 1A.	Uncharacterized protein.	0.603
CHMP1A	LOC108310005	ENSCCAP00000035245	ENSCCAP00000018559	Charged multivesicular body protein 1A.	Uncharacterized protein.	0.983
CHMP1A	MVB12A	ENSCCAP00000035245	ENSCCAP00000011472	Charged multivesicular body protein 1A.	Multivesicular body subunit 12A.	0.512
CHMP1A	MVB12B	ENSCCAP00000035245	ENSCCAP00000037234	Charged multivesicular body protein 1A.	Multivesicular body subunit 12B.	0.553
CHMP1A	SNF8	ENSCCAP00000035245	ENSCCAP00000016014	Charged multivesicular body protein 1A.	SNF8 subunit of ESCRT-II.	0.678
CHMP1A	STAM	ENSCCAP00000035245	ENSCCAP00000022445	Charged multivesicular body protein 1A.	Signal transducing adaptor molecule.	0.496
CHMP1A	TSG101	ENSCCAP00000035245	ENSCCAP00000036546	Charged multivesicular body protein 1A.	Tumor susceptibility 101.	0.684
CHMP1A	UBAP1	ENSCCAP00000035245	ENSCCAP00000019706	Charged multivesicular body protein 1A.	Ubiquitin associated protein 1.	0.540
CHMP1A	VPS25	ENSCCAP00000035245	ENSCCAP00000011011	Charged multivesicular body protein 1A.	Vacuolar protein sorting 25 homolog.	0.603