STRINGSTRING
CASQ2 CASQ2 HOMER2 HOMER2 SMPD1 SMPD1 HTR1B HTR1B CRHBP CRHBP FADD FADD DRD2 DRD2 SDK1 SDK1 TACR3 TACR3 CDK5 CDK5 ENSCCAP00000006464 ENSCCAP00000006464 LOC108291340 LOC108291340 PPP5C PPP5C ENSCCAP00000007329 ENSCCAP00000007329 PPP1R1B PPP1R1B ENSCCAP00000008341 ENSCCAP00000008341 CASP7 CASP7 ENSCCAP00000009063 ENSCCAP00000009063 RAD51 RAD51 RYR1 RYR1 BLM BLM SLC1A2 SLC1A2 BCL2L1 BCL2L1 LOC108315475 LOC108315475 SLC6A3 SLC6A3 PRKCG PRKCG PITX3 PITX3 SLC1A1 SLC1A1 ELAVL4 ELAVL4 GRM2 GRM2 CPT1A CPT1A FOSB FOSB EN1 EN1 OPRM1 OPRM1 DRD4 DRD4 PPP2R2A PPP2R2A LOC108299231 LOC108299231 ENSCCAP00000017458 ENSCCAP00000017458 SLC6A1 SLC6A1 MAP1LC3A MAP1LC3A PTK2B PTK2B LOC108283269 LOC108283269 PPP1R9B PPP1R9B LOC108294424 LOC108294424 TMEM38A TMEM38A PRKAA1 PRKAA1 DNM2 DNM2 CACNA1S CACNA1S DDC DDC ADORA2A ADORA2A PCSK1 PCSK1 TH TH ADCY8 ADCY8 PRKCE PRKCE CHEK1 CHEK1 RYR3 RYR3 TACR1 TACR1 LOC108311618 LOC108311618 SLC34A1 SLC34A1 TGM2 TGM2 HOMER1 HOMER1 SLC8A1 SLC8A1 SELENON SELENON ENSCCAP00000027088 ENSCCAP00000027088 RECQL5 RECQL5 DRD1 DRD1 CASP3 CASP3 CASP6 CASP6 SPIDR SPIDR TMEM38B TMEM38B OXT OXT ABAT ABAT CACNG4 CACNG4 CHRNB2 CHRNB2 ENSCCAP00000032665 ENSCCAP00000032665 CCNA2 CCNA2 HDAC2 HDAC2 ENSCCAP00000035780 ENSCCAP00000035780 PENK PENK SRR SRR EHMT2 EHMT2 SRSF9 SRSF9 SLC1A3 SLC1A3 RYR2 RYR2 TRPV1 TRPV1 DNMT3A DNMT3A DRD3 DRD3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CASQ2Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (402 aa)
HOMER2Homer scaffold protein 2. (351 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa)
HTR1B5-hydroxytryptamine receptor 1B. (391 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
FADDFAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
SDK1Sidekick cell adhesion molecule 1. (2215 aa)
TACR3Tachykinin receptor 3; Belongs to the G-protein coupled receptor 1 family. (461 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (322 aa)
ENSCCAP00000006464Uncharacterized protein. (60 aa)
LOC108291340Uncharacterized protein. (480 aa)
PPP5CSerine/threonine-protein phosphatase. (499 aa)
ENSCCAP00000007329HECT domain-containing protein. (51 aa)
PPP1R1BProtein phosphatase 1 regulatory inhibitor subunit 1B. (201 aa)
ENSCCAP00000008341HECT domain-containing protein. (624 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (304 aa)
ENSCCAP00000009063Uncharacterized protein; Belongs to the peptidase C14A family. (265 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
RYR1Ryanodine receptor 1. (4990 aa)
BLMBLM RecQ like helicase. (1401 aa)
SLC1A2Amino acid transporter. (509 aa)
BCL2L1BCL2 like 1. (233 aa)
LOC108315475C2 domain-containing protein. (141 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (687 aa)
PRKCGProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (698 aa)
PITX3Homeobox protein. (302 aa)
SLC1A1Amino acid transporter. (524 aa)
ELAVL4ELAV-like protein; Belongs to the RRM elav family. (402 aa)
GRM2Glutamate metabotropic receptor 2. (872 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
FOSBFosB proto-oncogene, AP-1 transcription factor subunit. (338 aa)
EN1Homeobox protein engrailed-like. (395 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (490 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (394 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (457 aa)
LOC108299231PALP domain-containing protein. (111 aa)
ENSCCAP00000017458HECT domain-containing protein. (498 aa)
SLC6A1Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (599 aa)
MAP1LC3AMicrotubule associated protein 1 light chain 3 alpha. (122 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (990 aa)
LOC108283269Uncharacterized protein; Belongs to the peptidase C14A family. (276 aa)
PPP1R9BProtein phosphatase 1 regulatory subunit 9B. (815 aa)
LOC108294424EF-hand domain-containing protein. (488 aa)
TMEM38ATransmembrane protein 38A. (300 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1877 aa)
DDCDopa decarboxylase. (480 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (413 aa)
PCSK1Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (753 aa)
THTyrosine hydroxylase. (527 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1249 aa)
PRKCEProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
CHEK1Checkpoint kinase 1; Belongs to the protein kinase superfamily. (476 aa)
RYR3Ryanodine receptor 3. (4853 aa)
TACR1Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
LOC108311618Uncharacterized protein. (454 aa)
SLC34A1Solute carrier family 34 member 1. (639 aa)
TGM2Transglutaminase 2. (687 aa)
HOMER1Homer scaffold protein 1. (357 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (600 aa)
SELENONEF-hand domain-containing protein. (561 aa)
ENSCCAP00000027088DUF4502 domain-containing protein. (204 aa)
RECQL5ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (990 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (446 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (277 aa)
CASP6Uncharacterized protein; Belongs to the peptidase C14A family. (293 aa)
SPIDRDUF4503 domain-containing protein. (397 aa)
TMEM38BTransmembrane protein 38B. (291 aa)
OXTOxytocin/neurophysin I prepropeptide. (125 aa)
ABAT4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (500 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
CHRNB2Cholinergic receptor nicotinic beta 2 subunit. (502 aa)
ENSCCAP00000032665G_PROTEIN_RECEP_F1_2 domain-containing protein. (138 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (432 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
ENSCCAP00000035780HECT domain-containing protein. (686 aa)
PENKProenkephalin. (267 aa)
SRRPALP domain-containing protein. (215 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1268 aa)
SRSF9Serine and arginine rich splicing factor 9. (221 aa)
SLC1A3Amino acid transporter. (542 aa)
RYR2Ryanodine receptor 2. (4922 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (839 aa)
DNMT3ADNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (912 aa)
DRD3Dopamine receptor D3. (248 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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