46 items (Cebus capucinus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RPS6KB1	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
	DRD2	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
	MKRN2	Makorin ring finger protein 2. (416 aa)
	TMEM100	Transmembrane protein 100. (134 aa)
	SOX9	SRY-box transcription factor 9. (509 aa)
	EPHA2	EPH receptor A2. (976 aa)
	ZFP36L1	ZFP36 ring finger protein like 1. (338 aa)
	NRG1	Neuregulin 1. (713 aa)
	AKT1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (489 aa)
	LOX	Lysyl oxidase. (417 aa)
	TYRO3	TYRO3 protein tyrosine kinase. (890 aa)
	CD28	CD28 molecule. (220 aa)
	THEM4	Thioesterase superfamily member 4. (242 aa)
	IGF1	Insulin like growth factor 1. (199 aa)
	C1QTNF12	C1q and TNF related 12. (287 aa)
	TSC2	TSC complex subunit 2. (1777 aa)
	BANK1	B cell scaffold protein with ankyrin repeats 1. (797 aa)
	PAX2	Paired box 2. (417 aa)
	PEAR1	Platelet endothelial aggregation receptor 1. (1036 aa)
	FLCN	Folliculin. (616 aa)
	SESN2	Sestrin 2. (480 aa)
	CD40	CD40 molecule. (274 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (314 aa)
	GAS6	Growth arrest specific 6. (676 aa)
	LINGO1	Leucine rich repeat and Ig domain containing 1. (620 aa)
	ADTRP	Androgen dependent TFPI regulating protein. (248 aa)
	SETX	Senataxin. (2678 aa)
	IL1B	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
	NKX3-1	NK3 homeobox 1. (223 aa)
	MT3	Metallothionein 3; Belongs to the metallothionein superfamily. Type 1 family. (113 aa)
	RPS6KB2	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (486 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	TNF	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (232 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	KDR	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
	MERTK	Receptor protein-tyrosine kinase. (940 aa)
	PIK3C2B	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1634 aa)
	SMPD3	Sphingomyelin phosphodiesterase 3. (655 aa)
	STK3	Serine/threonine kinase 3. (523 aa)
	AXL	AXL receptor tyrosine kinase. (896 aa)
	PIK3R3	Uncharacterized protein. (577 aa)
	SIRT2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa)
	PTEN	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
	TNFSF11	Tumor necrosis factor ligand superfamily member. (317 aa)
	LOC108297250-2	Uncharacterized protein. (529 aa)
	DLG1	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (926 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSCCAP00000034600	ENSCCAP00000019898	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.984
AKT1	CD28	ENSCCAP00000034600	ENSCCAP00000035899	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	CD28 molecule.	0.432
AKT1	GAS6	ENSCCAP00000034600	ENSCCAP00000026447	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Growth arrest specific 6.	0.434
AKT1	IGF1	ENSCCAP00000034600	ENSCCAP00000037209	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Insulin like growth factor 1.	0.622
AKT1	IL1B	ENSCCAP00000034600	ENSCCAP00000023501	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.535
AKT1	NKX3-1	ENSCCAP00000034600	ENSCCAP00000022740	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	NK3 homeobox 1.	0.946
AKT1	PIK3CA	ENSCCAP00000034600	ENSCCAP00000020641	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.986
AKT1	PIK3R3	ENSCCAP00000034600	ENSCCAP00000012892	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.955
AKT1	PTEN	ENSCCAP00000034600	ENSCCAP00000007387	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.	0.797
AKT1	RPS6KB1	ENSCCAP00000034600	ENSCCAP00000005204	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.973
AKT1	RPS6KB2	ENSCCAP00000034600	ENSCCAP00000021042	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.958
AKT1	TGFB1	ENSCCAP00000034600	ENSCCAP00000026494	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.541
AKT1	THEM4	ENSCCAP00000034600	ENSCCAP00000036923	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Thioesterase superfamily member 4.	0.981
AKT1	TNF	ENSCCAP00000034600	ENSCCAP00000020119	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.585
AKT1	TSC2	ENSCCAP00000034600	ENSCCAP00000038471	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	TSC complex subunit 2.	0.969
AKT1	ZFP36L1	ENSCCAP00000034600	ENSCCAP00000001169	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	ZFP36 ring finger protein like 1.	0.494
AKT2	AKT1	ENSCCAP00000019898	ENSCCAP00000034600	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.984
AKT2	IGF1	ENSCCAP00000019898	ENSCCAP00000037209	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Insulin like growth factor 1.	0.458
AKT2	NKX3-1	ENSCCAP00000019898	ENSCCAP00000022740	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	NK3 homeobox 1.	0.942
AKT2	PIK3CA	ENSCCAP00000019898	ENSCCAP00000020641	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.972