STRINGSTRING
PIK3R1 PIK3R1 CORO1A CORO1A IRS2 IRS2 PIK3IP1 PIK3IP1 INSR INSR FAM83A FAM83A DCAF8L1 DCAF8L1 DAB1 DAB1 AXL AXL FBXL2 FBXL2 DAB2IP DAB2IP GSN GSN DNM2 DNM2 PTPN13 PTPN13 DCAF8 DCAF8 NLRC3 NLRC3 HCST HCST CBL CBL LCK LCK IGF1R IGF1R PIK3AP1 PIK3AP1 PDGFRB PDGFRB FBXO41 FBXO41 TYRO3 TYRO3 IRS4 IRS4 FBXL20 FBXL20 FAM83B FAM83B INSRR INSRR PIK3R2 PIK3R2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (461 aa)
IRS2Insulin receptor substrate 2. (1361 aa)
PIK3IP1Phosphoinositide-3-kinase interacting protein 1. (263 aa)
INSRTyrosine-protein kinase receptor. (1352 aa)
FAM83AFamily with sequence similarity 83 member A. (280 aa)
DCAF8L1DDB1 and CUL4 associated factor 8 like 1. (577 aa)
DAB1DAB adaptor protein 1. (588 aa)
AXLAXL receptor tyrosine kinase. (896 aa)
FBXL2F-box and leucine rich repeat protein 2. (425 aa)
DAB2IPDAB2 interacting protein. (1193 aa)
GSNGelsolin. (782 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
PTPN13Protein tyrosine phosphatase non-receptor type 13. (2492 aa)
DCAF8DDB1 and CUL4 associated factor 8. (596 aa)
NLRC3NLR family CARD domain containing 3. (1095 aa)
HCSTHematopoietic cell signal transducer. (91 aa)
CBLCbl proto-oncogene. (909 aa)
LCKTyrosine-protein kinase. (515 aa)
IGF1RTyrosine-protein kinase receptor. (1285 aa)
PIK3AP1Phosphoinositide-3-kinase adaptor protein 1. (805 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1108 aa)
FBXO41F-box protein 41. (875 aa)
TYRO3TYRO3 protein tyrosine kinase. (890 aa)
IRS4Insulin receptor substrate 4. (1253 aa)
FBXL20F-box and leucine rich repeat protein 20. (417 aa)
FAM83BFamily with sequence similarity 83 member B. (1010 aa)
INSRRTyrosine-protein kinase receptor. (1301 aa)
PIK3R2Uncharacterized protein. (727 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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