102 items (Cebus capucinus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

Your Input:
	C14orf39	Chromosome 14 open reading frame 39. (587 aa)
	ENSCCAP00000000393	Uncharacterized protein. (145 aa)
	AGO4	Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (861 aa)
	NCAPH2	Non-SMC condensin II complex subunit H2. (570 aa)
	STAG2	Stromal antigen 2. (1242 aa)
	LOC108286105	Uncharacterized protein. (202 aa)
	SYCP2	Synaptonemal complex protein 2. (1511 aa)
	ACTR3B	Uncharacterized protein; Belongs to the actin family. (418 aa)
	ANKLE1	Ankyrin repeat and LEM domain containing 1. (665 aa)
	SPATA22	Spermatogenesis associated 22. (363 aa)
	MLH1	MutL homolog 1. (757 aa)
	CCNE1	Cyclin E1; Belongs to the cyclin family. (410 aa)
	CCNE2	Cyclin E2; Belongs to the cyclin family. (404 aa)
	STAG3	Stromal antigen 3. (1247 aa)
	MUS81	MUS81 structure-specific endonuclease subunit. (552 aa)
	NDC1	NDC1 transmembrane nucleoporin. (776 aa)
	SUN1	Sad1 and UNC84 domain containing 1. (813 aa)
	PTTG2	Pituitary tumor-transforming 2. (137 aa)
	LOC108297589	Uncharacterized protein. (430 aa)
	DMC1	Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (311 aa)
	ENSCCAP00000009590	Rad21_Rec8 domain-containing protein. (546 aa)
	SPO11	SPO11 initiator of meiotic double stranded breaks. (396 aa)
	TERF1	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (376 aa)
	CENPX	Uncharacterized protein. (81 aa)
	SMC4	Structural maintenance of chromosomes protein. (1287 aa)
	RNF212B	Ring finger protein 212B. (275 aa)
	SGO1	Shugoshin 1. (522 aa)
	REC8	REC8 meiotic recombination protein. (548 aa)
	TERB1	Telomere repeat binding bouquet formation protein 1. (695 aa)
	LOC108317875	RECA_2 domain-containing protein. (351 aa)
	CCNB1IP1	RING-type domain-containing protein. (277 aa)
	SLX4	SLX4 structure-specific endonuclease subunit. (1826 aa)
	BRIP1	BRCA1 interacting protein C-terminal helicase 1. (1212 aa)
	ESPL1	Extra spindle pole bodies like 1, separase. (2102 aa)
	MEIOB	Meiosis specific with OB-fold. (455 aa)
	TEX12	Testis expressed 12. (123 aa)
	PPP2R1A	Protein phosphatase 2 scaffold subunit Aalpha. (589 aa)
	ENSCCAP00000015138	TRF domain-containing protein. (250 aa)
	ANKRD31	Ankyrin repeat domain 31. (1929 aa)
	TOP2A	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1531 aa)
	M1AP	Meiosis 1 associated protein. (530 aa)
	MEI4	Meiotic double-stranded break formation protein 4. (384 aa)
	FANCM	FA complementation group M. (1992 aa)
	BUB1B	BUB1 N-terminal domain-containing protein. (1039 aa)
	MEIKIN	Meiotic kinetochore factor. (346 aa)
	PLK1	Serine/threonine-protein kinase PLK. (602 aa)
	SYCE1L	Synaptonemal complex central element protein 1 like. (188 aa)
	EME2	Essential meiotic structure-specific endonuclease subunit 2. (372 aa)
	SYCE1	Synaptonemal complex central element protein 1. (333 aa)
	HORMAD1	HORMA domain containing 1. (319 aa)
	HORMAD2	HORMA domain containing 2. (307 aa)
	ATM	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3000 aa)
	MLH3	MutL homolog 3. (1456 aa)
	CCDC155	Coiled-coil domain containing 155. (560 aa)
	TOP2B	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1619 aa)
	ACTR3	Actin related protein 3; Belongs to the actin family. (427 aa)
	ENSCCAP00000024677	RING-type domain-containing protein. (259 aa)
	SEPTIN1	Septin 1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (392 aa)
	CCDC36	Coiled-coil domain containing 36. (600 aa)
	TEX15	Testis expressed 15, meiosis and synapsis associated. (3175 aa)
	TERB2	Telomere repeat binding bouquet formation protein 2. (221 aa)
	LOC108306685	Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (188 aa)
	ENSCCAP00000028238	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (422 aa)
	SGO2	Shugoshin 2. (1259 aa)
	ENSCCAP00000029615	Mnd1 domain-containing protein. (155 aa)
	C1orf146	Chromosome 1 open reading frame 146. (180 aa)
	SHOC1	Shortage in chiasmata 1. (1444 aa)
	HFM1	Helicase for meiosis 1. (1433 aa)
	ERCC4	ERCC excision repair 4, endonuclease catalytic subunit. (916 aa)
	RAD51C	RECA_2 domain-containing protein. (352 aa)
	CENPC	Centromere protein C. (945 aa)
	MAEL	Maelstrom spermatogenic transposon silencer. (434 aa)
	MND1	Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (207 aa)
	BUB1	BUB1 mitotic checkpoint serine/threonine kinase. (1066 aa)
	TEX11	Uncharacterized protein. (494 aa)
	SMC1A	Structural maintenance of chromosomes protein. (1233 aa)
	ENSCCAP00000031489	HTH myb-type domain-containing protein. (287 aa)
	SYCE2	Synaptonemal complex central element protein 2. (178 aa)
	MSH5	DNA_MISMATCH_REPAIR_2 domain-containing protein. (833 aa)
	BAG6	BCL2 associated athanogene 6. (1146 aa)
	SYCP1	Synaptonemal complex protein 1. (976 aa)
	SMC2	Structural maintenance of chromosomes protein. (1182 aa)
	NCAPH	Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (741 aa)
	MSH4	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (870 aa)
	MAJIN	Membrane anchored junction protein. (214 aa)
	PSMC3IP	PSMC3 interacting protein. (217 aa)
	SIRT7	Sirtuin 7. (421 aa)
	RAD21	RAD21 cohesin complex component. (605 aa)
	SYCE3	Synaptonemal complex central element protein 3. (88 aa)
	ENSCCAP00000034559	Mnd1 domain-containing protein. (127 aa)
	EHMT2	Euchromatic histone lysine methyltransferase 2. (1268 aa)
	NUF2	NUF2 component of NDC80 kinetochore complex. (464 aa)
	TRIP13	Thyroid hormone receptor interactor 13; Belongs to the AAA ATPase family. (413 aa)
	MEIOC	Meiosis specific with coiled-coil domain. (953 aa)
	FANCD2	FA complementation group D2. (1442 aa)
	P3H4	Prolyl 3-hydroxylase family member 4 (non-enzymatic). (437 aa)
	CENPS	Centromere protein S. (138 aa)
	CORT	Cortistatin. (105 aa)
	ZCWPW1	Zinc finger CW-type and PWWP domain containing 1. (620 aa)
	RNF212	Ring finger protein 212. (253 aa)
	STAG1	Stromal antigen 1. (1267 aa)
	PTTG1	Uncharacterized protein. (144 aa)

Your Current Organism:

Cebus capucinus

NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTR3	ACTR3B	ENSCCAP00000024296	ENSCCAP00000004105	Actin related protein 3; Belongs to the actin family.	Uncharacterized protein; Belongs to the actin family.	0.976
ACTR3B	ACTR3	ENSCCAP00000004105	ENSCCAP00000024296	Uncharacterized protein; Belongs to the actin family.	Actin related protein 3; Belongs to the actin family.	0.976
ANKRD31	CCDC36	ENSCCAP00000015973	ENSCCAP00000024812	Ankyrin repeat domain 31.	Coiled-coil domain containing 36.	0.526
ANKRD31	SYCE1	ENSCCAP00000015973	ENSCCAP00000020291	Ankyrin repeat domain 31.	Synaptonemal complex central element protein 1.	0.449
ANKRD31	SYCE2	ENSCCAP00000015973	ENSCCAP00000031925	Ankyrin repeat domain 31.	Synaptonemal complex central element protein 2.	0.403
ANKRD31	SYCP1	ENSCCAP00000015973	ENSCCAP00000032513	Ankyrin repeat domain 31.	Synaptonemal complex protein 1.	0.489
ANKRD31	TEX15	ENSCCAP00000015973	ENSCCAP00000025766	Ankyrin repeat domain 31.	Testis expressed 15, meiosis and synapsis associated.	0.403
ATM	BRIP1	ENSCCAP00000021607	ENSCCAP00000013780	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	BRCA1 interacting protein C-terminal helicase 1.	0.740
ATM	DMC1	ENSCCAP00000021607	ENSCCAP00000008970	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily.	0.625
ATM	EME2	ENSCCAP00000021607	ENSCCAP00000020238	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Essential meiotic structure-specific endonuclease subunit 2.	0.420
ATM	ENSCCAP00000000393	ENSCCAP00000021607	ENSCCAP00000000393	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Uncharacterized protein.	0.625
ATM	ENSCCAP00000015138	ENSCCAP00000021607	ENSCCAP00000015138	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	TRF domain-containing protein.	0.409
ATM	ENSCCAP00000028238	ENSCCAP00000021607	ENSCCAP00000028238	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.	0.409
ATM	ENSCCAP00000031489	ENSCCAP00000021607	ENSCCAP00000031489	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	HTH myb-type domain-containing protein.	0.409
ATM	ERCC4	ENSCCAP00000021607	ENSCCAP00000030387	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	ERCC excision repair 4, endonuclease catalytic subunit.	0.779
ATM	FANCD2	ENSCCAP00000021607	ENSCCAP00000037517	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	FA complementation group D2.	0.760
ATM	FANCM	ENSCCAP00000021607	ENSCCAP00000017600	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	FA complementation group M.	0.729
ATM	LOC108317875	ENSCCAP00000021607	ENSCCAP00000013129	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	RECA_2 domain-containing protein.	0.752
ATM	MEIOB	ENSCCAP00000021607	ENSCCAP00000014680	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	Meiosis specific with OB-fold.	0.726
ATM	MLH1	ENSCCAP00000021607	ENSCCAP00000004766	Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...]	MutL homolog 1.	0.867