STRINGSTRING
TMEM64 TMEM64 SFRP1 SFRP1 TLCD3B TLCD3B SIRT1 SIRT1 PIM1 PIM1 JDP2 JDP2 WIF1 WIF1 PTGS2 PTGS2 XBP1 XBP1 INSIG1 INSIG1 ALOX5 ALOX5 LRP3 LRP3 ASXL2 ASXL2 LGALS12 LGALS12 ARNTL ARNTL TRIO TRIO TRPM4 TRPM4 SFRP2 SFRP2 PPARG PPARG ZFP36L2 ZFP36L2 ATAT1 ATAT1 ENSCCAP00000018890 ENSCCAP00000018890 TRIB3 TRIB3 DUSP10 DUSP10 STK4 STK4 ZADH2 ZADH2 SULT1E1 SULT1E1 FNDC5 FNDC5 RORA RORA WNT5A WNT5A CCDC71L CCDC71L ID4 ID4 C1QL4 C1QL4 LMO3 LMO3 CCN4 CCN4 TFE3 TFE3 TRPV4 TRPV4 STK3 STK3 RUNX1T1 RUNX1T1 ANKRD26 ANKRD26 CREB1 CREB1 SORT1 SORT1 ENSCCAP00000013648 ENSCCAP00000013648 GDF3 GDF3 ENSCCAP00000013029 ENSCCAP00000013029 SNAI2 SNAI2 GATA2 GATA2 TPH1 TPH1 ZC3H12A ZC3H12A SAV1 SAV1 TGFB1I1 TGFB1I1 VSTM2A VSTM2A FFAR4 FFAR4 ENSCCAP00000011133 ENSCCAP00000011133 ENSCCAP00000011029 ENSCCAP00000011029 ASXL1 ASXL1 RORC RORC ENSCCAP00000010913 ENSCCAP00000010913 AXIN2 AXIN2 ENSCCAP00000010332 ENSCCAP00000010332 NOCT NOCT GPS2 GPS2 FERMT2 FERMT2 SIRT2 SIRT2 BMP7 BMP7 RREB1 RREB1 ENPP1 ENPP1 SIX1 SIX1 SIRT6 SIRT6 LOC108297694 LOC108297694 CREBL2 CREBL2 ZBTB7B ZBTB7B SMAD3 SMAD3 CARM1 CARM1 HTR2A HTR2A TAF8 TAF8 AXIN1 AXIN1 CEBPB CEBPB NAPEPLD NAPEPLD BMP2 BMP2 TRIB2 TRIB2 LOC108282717 LOC108282717 WNT3A WNT3A ZFP36L1 ZFP36L1 CCDC85B CCDC85B JAG1 JAG1 GATA3 GATA3 FRZB FRZB ZBTB16 ZBTB16 SOX13 SOX13 RARRES2 RARRES2 DDIT3 DDIT3 TGFB1 TGFB1 WNT1 WNT1 ADIPOQ ADIPOQ MAPK14 MAPK14 ZFPM2 ZFPM2 NR1D1 NR1D1 E2F1 E2F1 CCDC3 CCDC3 GPER1 GPER1 LEP LEP FLCN FLCN DLK2 DLK2 WWTR1 WWTR1 ZNF385A ZNF385A PTPRQ PTPRQ ZFP36 ZFP36 MEX3C MEX3C SYAP1 SYAP1 PPARD PPARD MMP11 MMP11 GNB3 GNB3 KLF5 KLF5 ZBTB7C ZBTB7C FNDC3B FNDC3B YAP1 YAP1 AKT1 AKT1 WDFY2 WDFY2 ADIRF ADIRF MEDAG MEDAG ZFPM1 ZFPM1 CDS1 CDS1 LOC108282374 LOC108282374 LPL LPL FOXO1 FOXO1 METRNL METRNL HDAC6 HDAC6 WNT10B WNT10B HNRNPU HNRNPU ADIG ADIG AAMDC AAMDC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TMEM64Transmembrane protein 64. (379 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
TLCD3BTLC domain containing 3B. (274 aa)
SIRT1Sirtuin 1. (446 aa)
PIM1Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (313 aa)
JDP2Jun dimerization protein 2. (175 aa)
WIF1WNT inhibitory factor 1. (379 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
XBP1BZIP domain-containing protein. (375 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (277 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
LRP3LDL receptor related protein 3. (770 aa)
ASXL2ASXL transcriptional regulator 2. (1439 aa)
LGALS12Galectin. (275 aa)
ARNTLUncharacterized protein. (629 aa)
TRIOTrio Rho guanine nucleotide exchange factor. (3098 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1214 aa)
SFRP2Secreted frizzled related protein 2. (296 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
ZFP36L2ZFP36 ring finger protein like 2. (493 aa)
ATAT1Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] (423 aa)
ENSCCAP00000018890ANK_REP_REGION domain-containing protein. (530 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
DUSP10Dual specificity phosphatase 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa)
STK4Serine/threonine kinase 4. (487 aa)
ZADH2Zinc binding alcohol dehydrogenase domain containing 2. (378 aa)
SULT1E1Sulfotransferase; Belongs to the sulfotransferase 1 family. (294 aa)
FNDC5Fibronectin type III domain containing 5. (212 aa)
RORARAR related orphan receptor A. (489 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
CCDC71LUncharacterized protein. (293 aa)
ID4Inhibitor of DNA binding 4, HLH protein. (161 aa)
C1QL4Complement C1q like 4. (238 aa)
LMO3LIM domain only 3. (155 aa)
CCN4Cellular communication network factor 4. (367 aa)
TFE3Transcription factor binding to IGHM enhancer 3. (575 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (870 aa)
STK3Serine/threonine kinase 3. (523 aa)
RUNX1T1RUNX1 partner transcriptional co-repressor 1. (662 aa)
ANKRD26Ankyrin repeat domain 26. (1705 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
SORT1Sortilin. (831 aa)
ENSCCAP00000013648Uncharacterized protein. (138 aa)
GDF3Growth differentiation factor 3. (364 aa)
ENSCCAP00000013029CCDC144C domain-containing protein. (1062 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
GATA2GATA binding protein 2. (480 aa)
TPH1Tryptophan hydroxylase 1. (444 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (598 aa)
SAV1Salvador family WW domain containing protein 1. (384 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (461 aa)
VSTM2AV-set and transmembrane domain containing 2A. (303 aa)
FFAR4Free fatty acid receptor 4. (377 aa)
ENSCCAP00000011133Uncharacterized protein. (517 aa)
ENSCCAP00000011029Uncharacterized protein. (286 aa)
ASXL1ASXL transcriptional regulator 1. (1541 aa)
RORCRAR related orphan receptor C. (522 aa)
ENSCCAP00000010913SPRY domain-containing protein. (494 aa)
AXIN2Axin 2. (842 aa)
ENSCCAP00000010332Uncharacterized protein. (139 aa)
NOCTNocturnin. (431 aa)
GPS2G protein pathway suppressor 2. (327 aa)
FERMT2Fermitin family member 2. (693 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa)
BMP7Bone morphogenetic protein 7. (430 aa)
RREB1Ras responsive element binding protein 1. (1744 aa)
ENPP1Ectonucleotide pyrophosphatase/phosphodiesterase 1. (925 aa)
SIX1SIX homeobox 1. (284 aa)
SIRT6Sirtuin 6. (382 aa)
LOC108297694ANK_REP_REGION domain-containing protein. (307 aa)
CREBL2cAMP responsive element binding protein like 2. (123 aa)
ZBTB7BZinc finger and BTB domain containing 7B. (573 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
CARM1Coactivator associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (609 aa)
HTR2A5-hydroxytryptamine receptor 2A. (471 aa)
TAF8TATA-box binding protein associated factor 8. (312 aa)
AXIN1Axin 1. (867 aa)
CEBPBCCAAT/enhancer-binding protein. (345 aa)
NAPEPLDN-acyl phosphatidylethanolamine phospholipase D. (393 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
TRIB2Tribbles pseudokinase 2. (343 aa)
LOC108282717UBP-type domain-containing protein. (1057 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
ZFP36L1ZFP36 ring finger protein like 1. (338 aa)
CCDC85BCoiled-coil domain containing 85B. (202 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
GATA3GATA binding protein 3. (444 aa)
FRZBFrizzled related protein. (325 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
SOX13SRY-box transcription factor 13. (615 aa)
RARRES2Retinoic acid receptor responder 2. (161 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (314 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1151 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (615 aa)
E2F1E2F transcription factor 1. (438 aa)
CCDC3Coiled-coil domain containing 3. (270 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
FLCNFolliculin. (616 aa)
DLK2Delta like non-canonical Notch ligand 2. (383 aa)
WWTR1WW domain containing transcription regulator 1. (400 aa)
ZNF385AZinc finger protein 385A. (414 aa)
PTPRQProtein tyrosine phosphatase receptor type Q. (2333 aa)
ZFP36ZFP36 ring finger protein. (332 aa)
MEX3CMex-3 RNA binding family member C. (660 aa)
SYAP1Synapse associated protein 1. (283 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
MMP11Matrix metallopeptidase 11. (489 aa)
GNB3G protein subunit beta 3. (340 aa)
KLF5Kruppel like factor 5. (457 aa)
ZBTB7CZinc finger and BTB domain containing 7C. (620 aa)
FNDC3BFibronectin type III domain containing 3B. (1199 aa)
YAP1Uncharacterized protein. (506 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (489 aa)
WDFY2WD repeat and FYVE domain containing 2. (400 aa)
ADIRFAdipogenesis regulatory factor. (76 aa)
MEDAGMesenteric estrogen dependent adipogenesis. (303 aa)
ZFPM1Zinc finger protein, FOG family member 1. (1001 aa)
CDS1Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (461 aa)
LOC108282374Uncharacterized protein. (330 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa)
FOXO1Forkhead box O1. (654 aa)
METRNLMeteorin like, glial cell differentiation regulator. (315 aa)
HDAC6Histone deacetylase 6. (1213 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (825 aa)
ADIGAdipogenin. (81 aa)
AAMDCAdipogenesis associated Mth938 domain containing. (136 aa)
Your Current Organism:
Cebus capucinus
NCBI taxonomy Id: 9516
Other names: C. capucinus, white-faced capuchin, white-faced sapajou, white-throated capuchin
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